BID Binds to Replication Protein A and Stimulates ATR Function following Replicative Stress

Bid can mediate a pro-apoptotic response to etoposide and ionizing radiation without cleavage in its unstructured loop and in the absence of p53

(2011) C Maas et al.   ONCOGENE

Structural Dynamics and Single-Stranded DNA Binding Activity of the Three N-Terminal Domains of the Large Subunit of Replication Protein A from Small Angle X-ray Scattering

(2010) Dalyir I. Pretto et al.   BIOCHEMISTRY

MCL-1 localizes to sites of DNA damage and regulates DNA damage response

(2010) Sarwat Jamil et al.   CELL CYCLE

ATM-dependent expression of IEX-1 controls nuclear accumulation of Mcl-1 and the DNA damage response

(2010) P Pawlikowska et al.   CELL DEATH AND DIFFERENTIATION

Proapoptotic Bid mediates the Atr-directed DNA damage response to replicative stress

(2010) Y Liu et al.   CELL DEATH AND DIFFERENTIATION

Continued primer synthesis at stalled replication forks contributes to checkpoint activation

(2010) Christopher Van et al.   JOURNAL OF CELL BIOLOGY

Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling

(2010) J.-H. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The S-phase checkpoint: targeting the replication fork

(2009) Mónica Segurado et al.   BIOLOGY OF THE CELL

The annealing helicase HARP protects stalled replication forks

(2009) J. Yuan et al.   GENES & DEVELOPMENT

The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart

(2009) A. Ciccia et al.   GENES & DEVELOPMENT

The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks

(2009) C. E. Bansbach et al.   GENES & DEVELOPMENT

The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA

(2009) T. Yusufzai et al.   GENES & DEVELOPMENT

BAD: undertaker by night, candyman by day

(2009) N N Danial   ONCOGENE

Aven-Dependent Activation of ATM Following DNA Damage

(2008) Jessie Yanxiang Guo et al.   CURRENT BIOLOGY

TopBP1 activates ATR through ATRIP and a PIKK regulatory domain

(2008) D. A. Mordes et al.   GENES & DEVELOPMENT

The Basic Cleft of RPA70N Binds Multiple Checkpoint Proteins, Including RAD9, To Regulate ATR Signaling

(2008) X. Xu et al.   MOLECULAR AND CELLULAR BIOLOGY

Caspase-2 Cleavage of BID Is a Critical Apoptotic Signal Downstream of Endoplasmic Reticulum Stress

(2008) J.-P. Upton et al.   MOLECULAR AND CELLULAR BIOLOGY

An Essential Role for MCL-1 in ATR-mediated CHK1 Phosphorylation

(2008) Sarwat Jamil et al.   MOLECULAR BIOLOGY OF THE CELL

Bcl2 Negatively Regulates DNA Double-Strand-Break Repair through a Nonhomologous End-Joining Pathway

(2008) Qinhong Wang et al.   MOLECULAR CELL

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

HARP Is an ATP-Driven Annealing Helicase

(2008) T. Yusufzai et al.   SCIENCE

Characterization of binding-induced changes in dynamics suggests a model for sequence-nonspecific binding of ssDNA by replication protein A

(2002) Shibani Bhattacharya et al.   PROTEIN SCIENCE