Upregulated Parkin expression protects mitochondrial homeostasis in DJ-1 konckdown cells and cells overexpressing the DJ-1 L166P mutation

ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons

(2012) Alvin P. Joselin et al.   HUMAN MOLECULAR GENETICS

Parkinson’s disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

(2012) Xinglong Wang et al.   JOURNAL OF NEUROCHEMISTRY

L166P mutant DJ-1 promotes cell death by dissociating Bax from mitochondrial Bcl-XL

(2012) Haigang Ren et al.   Molecular Neurodegeneration

DJ-1 Null Dopaminergic Neuronal Cells Exhibit Defects in Mitochondrial Function and Structure: Involvement of Mitochondrial Complex I Assembly

(2012) Jun Young Heo et al.   PLoS One

DJ-1 modulates the expression of Cu/Zn-superoxide dismutase-1 through the Erk1/2-Elk1 pathway in neuroprotection

(2011) Zhiquan Wang et al.   ANNALS OF NEUROLOGY

PINK1-parkin-dependent mitophagy involves ubiquitination of mitofusins 1 and 2: Implications for Parkinson disease pathogenesis

(2011) Matthew E. Gegg et al.   Autophagy

Reduced protein stability of human DJ-1/PARK7 L166P, linked to autosomal recessive Parkinson disease, is due to direct endoproteolytic cleavage by the proteasome

(2011) Beatriz Alvarez-Castelao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons

(2011) Wendou Yu et al.   HUMAN MOLECULAR GENETICS

Parkin Ubiquitinates Drp1 for Proteasome-dependent Degradation

(2011) Hongxia Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1

(2011) Liliane Glauser et al.   JOURNAL OF NEUROCHEMISTRY

DJ-1 mediates paraquat-induced dopaminergic neuronal cell death

(2011) Hyun Joo Kwon et al.   TOXICOLOGY LETTERS

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

(2010) Kelly Jean Thomas et al.   HUMAN MOLECULAR GENETICS

DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex

(2010) Joo-Young Im et al.   NEUROSCIENCE RESEARCH

DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function

(2010) L.-Y. Hao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DJ-1 binds to mitochondrial complex I and maintains its activity

(2009) Takuya Hayashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio)

(2009) L. Flinn et al.   BRAIN

Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release

(2009) A. K. Berger et al.   HUMAN MOLECULAR GENETICS

Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair

(2009) Oliver Rothfuss et al.   HUMAN MOLECULAR GENETICS

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

(2009) Hui Xiong et al.   JOURNAL OF CLINICAL INVESTIGATION

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial function and morphology are impaired inparkin-mutant fibroblasts

(2008) Heather Mortiboys et al.   ANNALS OF NEUROLOGY

DJ-1 modulates UV-induced oxidative stress signaling through the suppression of MEKK1 and cell death

(2008) J-S Mo et al.   CELL DEATH AND DIFFERENTIATION

Aggresome-forming TTRAP mediates pro-apoptotic properties of Parkinson's disease-associated DJ-1 missense mutations

(2008) S Zucchelli et al.   CELL DEATH AND DIFFERENTIATION

Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1α: regulation by SUMOylation and oxidation

(2008) Nan Zhong et al.   HUMAN MOLECULAR GENETICS

Mitochondrial localization of DJ-1 leads to enhanced neuroprotection

(2008) Eunsung Junn et al.   JOURNAL OF NEUROSCIENCE RESEARCH

DJ-1 Modulates α-Synuclein Aggregation State in a Cellular Model of Oxidative Stress: Relevance for Parkinson's Disease and Involvement of HSP70

(2008) Sara Batelli et al.   PLoS One

The PINK1/Parkin pathway regulates mitochondrial morphology

(2008) A. C. Poole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA