Histone deacetylases inhibitor trichostatin A increases the expression of Dleu2/miR-15a/16-1 via HDAC3 in non-small cell lung cancer

DICER1, DROSHA and miRNAs in patients with non-small cell lung cancer: implications for outcomes and histologic classification

(2013) C. Vanesa Díaz-García et al.   CARCINOGENESIS

Inhibition of class I histone deacetylases in non-small cell lung cancer by honokiol leads to suppression of cancer cell growth and induction of cell death in vitro and in vivo

(2012) Tripti Singh et al.   Epigenetics

Targeting signaling pathways in lung cancer therapy

(2012) William CS Cho   EXPERT OPINION ON THERAPEUTIC TARGETS

HDAC2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteins

(2012) Kwang Hwa Jung et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cancer epigenetics: linking basic biology to clinical medicine

(2011) Hsing-Chen Tsai et al.   CELL RESEARCH

Promises and challenges in developing miRNA as a molecular diagnostic tool for lung cancer

(2011) William CS Cho   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner

(2011) Nora Bandi et al.   Molecular Cancer

Synergistic apoptosis induction in leukemic cells by miR-15a/16-1 and arsenic trioxide

(2010) Shen-meng Gao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bcl-2 and β1-integrin predict survival in a tissue microarray of small cell lung cancer

(2010) M H Lawson et al.   BRITISH JOURNAL OF CANCER

HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling

(2010) Cassandra A. Godman et al.   CANCER BIOLOGY & THERAPY

Aurora A, Aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer

(2010) Xu-Hui Zhang et al.   CANCER BIOLOGY & THERAPY

Type-specific roles of histone deacetylase (HDAC) overexpression in ovarian carcinoma: HDAC1 enhances cell proliferation and HDAC3 stimulates cell migration with downregulation of E-cadherin

(2010) Akiko Hayashi et al.   INTERNATIONAL JOURNAL OF CANCER

Prognostic implications of miR-16 expression levels in resected non-small-cell lung cancer

(2010) Alfons Navarro et al.   JOURNAL OF SURGICAL ONCOLOGY

Combinations of DNA Methyltransferase and Histone Deacetylase Inhibitors Induce DNA Damage in Small Cell Lung Cancer Cells: Correlation of Resistance with IFN-Stimulated Gene Expression

(2010) Wioleta Luszczek et al.   MOLECULAR CANCER THERAPEUTICS

Histone Deacetylase Inhibitors Downregulate Checkpoint Kinase 1 Expression to Induce Cell Death in Non-Small Cell Lung Cancer Cells

(2010) William Brazelle et al.   PLoS One

Strong expression of HDAC3 correlates with a poor prognosis in patients with adenocarcinoma of the lung

(2010) Yoshihiro Minamiya et al.   TUMOR BIOLOGY

miR-15a and miR-16 Are Implicated in Cell Cycle Regulation in a Rb-Dependent Manner and Are Frequently Deleted or Down-regulated in Non–Small Cell Lung Cancer

(2009) Nora Bandi et al.   CANCER RESEARCH

DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

(2009) Mikael Lerner et al.   EXPERIMENTAL CELL RESEARCH

Histone Deacetylase Inhibitors in Cancer Therapy

(2009) Andrew A. Lane et al.   JOURNAL OF CLINICAL ONCOLOGY

Carboplatin and Paclitaxel in Combination With Either Vorinostat or Placebo for First-Line Therapy of Advanced Non–Small-Cell Lung Cancer

(2009) Suresh S. Ramalingam et al.   JOURNAL OF CLINICAL ONCOLOGY

Prognostic value of miR-16 expression in childhood acute lymphoblastic leukemia relationships to normal and malignant lymphocyte proliferation

(2009) T. Kaddar et al.   LEUKEMIA RESEARCH

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Regression of murine lung tumors by the let-7 microRNA

(2009) P Trang et al.   ONCOGENE

miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells

(2008) Lin Xia et al.   INTERNATIONAL JOURNAL OF CANCER

Antitumor activity of histone deacetylase inhibitors in non-small cell lung cancer cells: development of a molecular predictive model

(2008) A. Miyanaga et al.   MOLECULAR CANCER THERAPEUTICS

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE

MiR-15a and miR-16-1 cluster functions in human leukemia

(2008) George A. Calin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA