AMP-activated protein kinase (AMPK)/Ulk1-dependent autophagic pathway contributes to C6 ceramide-induced cytotoxic effects in cultured colorectal cancer HT-29 cells

Anti-metastatic Treatment in Colorectal Cancer: Targeting Signaling Pathways

(2013) Clara Lemos et al.   CURRENT PHARMACEUTICAL DESIGN

Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells

(2012) Qing-you Zheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activation of reactive oxygen species/AMP activated protein kinase signaling mediates fisetin-induced apoptosis in multiple myeloma U266 cells

(2012) Ki Young Jang et al.   CANCER LETTERS

AMP-Activated Protein Kinase: A Target for Drugs both Ancient and Modern

(2012) D. Grahame Hardie et al.   CHEMISTRY & BIOLOGY

Patients' Expectations about Effects of Chemotherapy for Advanced Cancer

(2012) Jane C. Weeks et al.   NEW ENGLAND JOURNAL OF MEDICINE

Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression

(2011) Hak-Su Kim et al.   BIOCHEMICAL PHARMACOLOGY

C6-Ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth

(2011) Margaret Flowers et al.   BREAST CANCER RESEARCH AND TREATMENT

Co-administration of perifosine with paclitaxel synergistically induces apoptosis in ovarian cancer cells: More than just AKT inhibition

(2011) Hui Sun et al.   CANCER LETTERS

The multiple roles of autophagy in cancer

(2011) M. T. Rosenfeldt et al.   CARCINOGENESIS

Activation of AMP-Activated Protein Kinase Contributes to Doxorubicin-Induced Cell Death and Apoptosis in Cultured Myocardial H9c2 Cells

(2011) Min-Bin Chen et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Metformin Amplifies Chemotherapy-Induced AMPK Activation and Antitumoral Growth

(2011) G. Z. Rocha et al.   CLINICAL CANCER RESEARCH

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK

(2011) L. Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ceramide in Chemotherapy of Tumors

(2011) Marie-Therese Dimanche-Boitrel et al.   Recent Patents on Anti-Cancer Drug Discovery

Induction of apoptosis by quercetin is mediated through AMPKα1/ASK1/p38 pathway

(2010) Yun-Kyoung Lee et al.   CANCER LETTERS

Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance

(2010) Suriyan Ponnusamy et al.   Future Oncology

Activation of AMP-activated Protein Kinase by Temozolomide Contributes to Apoptosis in Glioblastoma Cells via p53 Activation and mTORC1 Inhibition

(2010) Wen-bin Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of AMP-activated protein kinase is involved in vincristine-induced cell apoptosis in B16 melanoma cell

(2010) Min-Bin Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition

(2010) C Ji et al.   ONCOGENE

The Association of AMPK with ULK1 Regulates Autophagy

(2010) Jong Woo Lee et al.   PLoS One

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate

(2008) C MAO   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway

(2008) C.-L. Chen et al.   BLOOD

The regulation of AMP-activated protein kinase by upstream kinases

(2008) D Carling et al.   INTERNATIONAL JOURNAL OF OBESITY

AMPK and Raptor: Matching Cell Growth to Energy Supply

(2008) D. Grahame Hardie   MOLECULAR CELL