Antioxidant effect of doxycycline decreases MMP activity and blood pressure in SHR

Recombinant Human Matrix Metalloproteinase-2 Impairs Cardiovascular β-Adrenergic Responses

(2013) Karina C. Ferraz et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Comprehensive Evaluation of the Effects of Enalapril on Matrix Metalloproteinases Levels in Hypertension

(2012) Vanessa Fontana et al.   CARDIOVASCULAR DRUGS AND THERAPY

Circulating matrix metalloproteinases and their inhibitors in hypertension

(2012) Vanessa Fontana et al.   CLINICA CHIMICA ACTA

Time course involvement of matrix metalloproteinases in the vascular alterations of renovascular hypertension

(2012) Carla S. Ceron et al.   MATRIX BIOLOGY

Doxycycline ameliorates 2K-1C hypertension-induced vascular dysfunction in rats by attenuating oxidative stress and improving nitric oxide bioavailability

(2012) Michele M. Castro et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Doxycycline, a matrix metalloprotease inhibitor, reduces vascular remodeling and damage after cerebral ischemia in stroke-prone spontaneously hypertensive rats

(2011) Paulo W. Pires et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Consistent Alterations of Circulating Matrix Metalloproteinases Levels in Untreated Hypertensives and in Spontaneously Hypertensive Rats: A Relevant Pharmacological Target

(2011) Vanessa Fontana et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Pyrrolidine dithiocarbamate down-regulates vascular matrix metalloproteinases and ameliorates vascular dysfunction and remodelling in renovascular hypertension

(2011) SBA Cau et al.   BRITISH JOURNAL OF PHARMACOLOGY

Matrix metalloproteinases: Targets for doxycycline to prevent the vascular alterations of hypertension

(2011) Michele M. Castro et al.   PHARMACOLOGICAL RESEARCH

Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature

(2010) Michael O. Griffin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Matrix metalloproteinases cleave the β2-adrenergic receptor in spontaneously hypertensive rats

(2010) Stephen F. Rodrigues et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Doxycycline Dose-dependently Inhibits MMP-2-Mediated Vascular Changes in 2K1C Hypertension

(2010) Danielle A. Guimaraes et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension

(2010) CS Ceron et al.   BRITISH JOURNAL OF PHARMACOLOGY

Reactive oxygen species activate and tetracyclines inhibit rat osteoblast collagenase

(2010) Nungavaram S. Ramamurthy et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Role of NF-κB in Flow-Induced Vascular Remodeling

(2009) Yves Castier et al.   ANTIOXIDANTS & REDOX SIGNALING

Antioxidant treatment reduces matrix metalloproteinase-2-induced vascular changes in renovascular hypertension

(2009) Michele M. Castro et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lercanidipine reduces matrix metalloproteinase-2 activity and reverses vascular dysfunction in renovascular hypertensive rats

(2008) Marcio L.L. Martinez et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats

(2007) Michele M. Castro et al.   ATHEROSCLEROSIS