Wnt/β-catenin signaling induces the aging of mesenchymal stem cells through promoting the ROS production

A crucial role for Nox 1 in redox-dependent regulation of Wnt-β-catenin signaling

(2012) Seheli Kajla et al.   FASEB JOURNAL

Particulate matter Air Pollution induces hypermethylation of the p16 promoter Via a mitochondrial ROS-JNK-DNMT1 pathway

(2012) Saul Soberanes et al.   Scientific Reports

The HDAC inhibitor depsipeptide transactivates the p53/p21 pathway by inducing DNA damage

(2011) Haiying Wang et al.   DNA REPAIR

Autophagy regulates ROS-induced cellular senescence via p21 in a p38 MAPKα dependent manner

(2011) Yi Luo et al.   EXPERIMENTAL GERONTOLOGY

Wnt/β-Catenin Signaling Induces the Aging of Mesenchymal Stem Cells through the DNA Damage Response and the p53/p21 Pathway

(2011) Da-yong Zhang et al.   PLoS One

The Wnt/beta-catenin pathway is activated during advanced arterial aging in humans

(2010) Alexandre Marchand et al.   AGING CELL

Wnt signaling regulates mitochondrial physiology and insulin sensitivity

(2010) J. C. Yoon et al.   GENES & DEVELOPMENT

Inhibiting NF-κB activation and ROS production are involved in the mechanism of silibinin's protection against D-galactose-induced senescence

(2010) Qiong Wang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Level of reactive oxygen species induced by p21WAF(1)/CIP(1)is critical for the determination of cell fate

(2009) Takafumi Inoue et al.   CANCER SCIENCE

Induction of Cellular Senescence by Secretory Phospholipase A2 in Human Dermal Fibroblasts through an ROS-Mediated p53 Pathway

(2009) H. J. Kim et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Downregulation of Wnt-Mediated ROS generation is causally implicated in leprechaunism

(2009) Ji Won Park et al.   MOLECULES AND CELLS

Which way does the Wnt blow? Exploring the duality of canonical Wnt signaling on cellular aging

(2008) Nathan A. DeCarolis et al.   BIOESSAYS

Base excision repair of oxidative DNA damage and association with cancer and aging

(2008) S. Maynard et al.   CARCINOGENESIS