Journal
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
Volume 183, Issue 1, Pages 1-7Publisher
ELSEVIER
DOI: 10.1016/j.molbiopara.2012.02.001
Keywords
Monoamines; Serotonin; Anthelmintic
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Funding
- NIAID NIH HHS [R01 AI072644, R01 AI072644-04] Funding Source: Medline
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This review is designed to summarize the information on monoamine-dependent paralysis as a target for anthelmintic development, examine the conservation of monoamine receptors in the genomes of both free-living and parasitic nematodes, and highlight the utility of the Caenorhabditis elegans model system for dissecting the monoaminergic modulation of locomotory decision-making. (C) 2012 Elsevier B.V. All rights reserved.
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