Hippocampal Extracellular Matrix Levels and Stochasticity in Synaptic Protein Expression Increase with Age and Are Associated with Age-dependent Cognitive Decline

ProteomeXchange provides globally coordinated proteomics data submission and dissemination

(2014) Juan A Vizcaíno et al.   NATURE BIOTECHNOLOGY

Depletion of Perineuronal Nets Enhances Recognition Memory and Long-Term Depression in the Perirhinal Cortex

(2013) C. Romberg et al.   JOURNAL OF NEUROSCIENCE

Spatio-temporal differences in perineuronal net expression in the mouse hippocampus, with reference to parvalbumin

(2013) J. Yamada et al.   NEUROSCIENCE

Targeting the neural extracellular matrix in neurological disorders

(2013) S. Soleman et al.   NEUROSCIENCE

Delayed treatment with chondroitinase ABC promotes sensorimotor recovery and plasticity after stroke in aged rats

(2012) Sara Soleman et al.   BRAIN

A rich environmental experience reactivates visual cortex plasticity in aged rats

(2012) Manuela Scali et al.   EXPERIMENTAL GERONTOLOGY

Synaptic Proteome Changes in a DNA Repair Deficient Ercc1 Mouse Model of Accelerated Aging

(2012) Marlene J. Végh et al.   JOURNAL OF PROTEOME RESEARCH

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Glutathione-S-transferase P1 is a critical regulator of Cdk5 kinase activity

(2011) Kai-Hui Sun et al.   JOURNAL OF NEUROCHEMISTRY

Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia

(2011) E S Lips et al.   MOLECULAR PSYCHIATRY

The Spatial Association of Gene Expression Evolves from Synchrony to Asynchrony and Stochasticity with Age

(2011) Qi Wang et al.   PLoS One

Variance of Gene Expression Identifies Altered Network Constraints in Neurological Disease

(2011) Jessica C. Mar et al.   PLoS Genetics

Functional Gene Group Analysis Reveals a Role of Synaptic Heterotrimeric G Proteins in Cognitive Ability

(2010) Dina Ruano et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Changes in molecular composition of rat medial prefrontal cortex synapses during adolescent development

(2010) Danielle S. Counotte et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Accurate Quantification of More Than 4000 Mouse Tissue Proteins Reveals Minimal Proteome Changes During Aging

(2010) Dirk M. Walther et al.   MOLECULAR & CELLULAR PROTEOMICS

Missing heritability and strategies for finding the underlying causes of complex disease

(2010) Evan E. Eichler et al.   NATURE REVIEWS GENETICS

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

(2010) S. Peleg et al.   SCIENCE

Senescent synapses and hippocampal circuit dynamics

(2010) Sara N. Burke et al.   TRENDS IN NEUROSCIENCES

Matrix Metalloproteinase-9 Controls NMDA Receptor Surface Diffusion through Integrin  1 Signaling

(2009) P. Michaluk et al.   JOURNAL OF NEUROSCIENCE

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Brain extracellular matrix affects AMPA receptor lateral mobility and short-term synaptic plasticity

(2009) Renato Frischknecht et al.   NATURE NEUROSCIENCE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Memory activation in healthy nonagenarians

(2009) Michal Schnaider Beeri et al.   NEUROBIOLOGY OF AGING

Perineuronal Nets Protect Fear Memories from Erasure

(2009) N. Gogolla et al.   SCIENCE

Sequence Reactivation in the Hippocampus Is Impaired in Aged Rats

(2008) J. L. Gerrard et al.   JOURNAL OF NEUROSCIENCE

Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking

(2008) Michel C Van den Oever et al.   NATURE NEUROSCIENCE

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH