The Human PDZome: A Gateway to PSD95-Disc Large-Zonula Occludens (PDZ)-mediated Functions

Prevalence, Specificity and Determinants of Lipid-Interacting PDZ Domains from an In-Cell Screen and In Vitro Binding Experiments

(2013) Ylva Ivarsson et al.   PLoS One

The Continuing Challenge of Understanding, Preventing, and Treating Neural Tube Defects

(2013) J. B. Wallingford et al.   SCIENCE

The PDZ-binding motif of MCC is phosphorylated at position −1 and controls lamellipodia formation in colon epithelial cells

(2012) Laurent Pangon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration

(2012) Valbona Luga et al.   CELL

Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear

(2012) A. P. Giese et al.   DEVELOPMENT

VANGL2 regulates membrane trafficking of MMP14 to control cell polarity and migration

(2012) B. B. Williams et al.   JOURNAL OF CELL SCIENCE

Genome-wide Functional Annotation of Dual-Specificity Protein- and Lipid-Binding Modules that Regulate Protein Interactions

(2012) Yong Chen et al.   MOLECULAR CELL

Molecular Characterisation of Endogenous Vangl2/Vangl1 Heteromeric Protein Complexes

(2012) Edwige Belotti et al.   PLoS One

Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia

(2011) J. B. Wallingford et al.   GENES & DEVELOPMENT

SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia

(2011) Helen B. Pearson et al.   JOURNAL OF CLINICAL INVESTIGATION

Emerging Theme: Cellular PDZ Proteins as Common Targets of Pathogenic Viruses

(2011) R. T. Javier et al.   JOURNAL OF VIROLOGY

Inhibition of Retromer Activity by Herpesvirus Saimiri Tip Leads to CD4 Downregulation and Efficient T Cell Transformation

(2011) D. Kingston et al.   JOURNAL OF VIROLOGY

Deficiency of Sorting Nexin 27 (SNX27) Leads to Growth Retardation and Elevated Levels of N-Methyl-D-Aspartate Receptor 2C (NR2C)

(2011) L. Cai et al.   MOLECULAR AND CELLULAR BIOLOGY

SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors

(2011) Paul Temkin et al.   NATURE CELL BIOLOGY

A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration and is associated with breast cancer progression

(2011) J N Anastas et al.   ONCOGENE

Genome-Wide Analysis of PDZ Domain Binding Reveals Inherent Functional Overlap within the PDZ Interaction Network

(2011) Aartjan J. W. te Velthuis et al.   PLoS One

Epithelial organization, cell polarity and tumorigenesis

(2011) Luke Martin McCaffrey et al.   TRENDS IN CELL BIOLOGY

A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding

(2010) Nicolas Lenfant et al.   BMC GENOMICS

Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b

(2010) C. Wansleeben et al.   DEVELOPMENT

SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane

(2010) Benjamin E.L. Lauffer et al.   JOURNAL OF CELL BIOLOGY

The PCP Pathway Instructs the Planar Orientation of Ciliated Cells in the Xenopus Larval Skin

(2009) Brian Mitchell et al.   CURRENT BIOLOGY

GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer

(2009) Kenneth L. Scott et al.   NATURE

Inhibition of Wnt signaling by Dishevelled PDZ peptides

(2009) Yingnan Zhang et al.   Nature Chemical Biology

BMP inhibition initiates neural induction via FGF signaling and Zic genes

(2009) L. Marchal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Signaling in Space and Time: Where Proteins Come Together and When They're Apart

(2009) J. D. Scott et al.   SCIENCE

Neuropilin-1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells

(2009) Donatella Valdembri et al.   PLOS BIOLOGY

Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

(2008) Lixing Zhan et al.   CELL

CASK Functions as a Mg2+-Independent Neurexin Kinase

(2008) Konark Mukherjee et al.   CELL

Scrib regulates PAK activity during the cell migration process

(2008) Sébastien Nola et al.   HUMAN MOLECULAR GENETICS

An empirical framework for binary interactome mapping

(2008) Kavitha Venkatesan et al.   NATURE METHODS

Cell polarity proteins: common targets for tumorigenic human viruses

(2008) R T Javier   ONCOGENE

Human papillomaviruses, cervical cancer and cell polarity

(2008) M Thomas et al.   ONCOGENE

A Specificity Map for the PDZ Domain Family

(2008) Raffi Tonikian et al.   PLOS BIOLOGY