Identification of Protein Interactions Involved in Cellular Signaling

Advancing formaldehyde cross-linking towards quantitative proteomic applications

(2012) Cordula Klockenbusch et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Identification and Functional Studies of a New Nrf2 Partner IQGAP1: A Critical Role in the Stability and Transactivation of Nrf2

(2012) Jung-Hwan Kim et al.   ANTIOXIDANTS & REDOX SIGNALING

Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

(2012) Mikko Taipale et al.   CELL

Chemical proteomics and its impact on the drug discovery process

(2012) Qing Miao et al.   Expert Review of Proteomics

From protein interaction networks to novel therapeutic strategies

(2012) Samira Jaeger et al.   IUBMB LIFE

High-Resolution Protein Interaction Map of the Drosophila melanogaster p38 Mitogen-Activated Protein Kinases Reveals Limited Functional Redundancy

(2012) V. E. Belozerov et al.   MOLECULAR AND CELLULAR BIOLOGY

Nucleolar AATF regulates c-Jun–mediated apoptosis

(2012) Saima E. Ferraris et al.   MOLECULAR BIOLOGY OF THE CELL

Sound medicine

(2012) Elie Dolgin   NATURE MEDICINE

CIP2A signature reveals the MYC dependency of CIP2A-regulated phenotypes and its clinical association with breast cancer subtypes

(2012) M Niemelä et al.   ONCOGENE

Structural Probing of a Protein Phosphatase 2A Network by Chemical Cross-Linking and Mass Spectrometry

(2012) F. Herzog et al.   SCIENCE

Membrane mechanisms for signal transduction: The coupling of the meso-scale raft domains to membrane-skeleton-induced compartments and dynamic protein complexes

(2012) Akihiro Kusumi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression

(2011) C. M. Lucas et al.   BLOOD

Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis

(2011) Florian Grebien et al.   CELL

Drug target deconvolution by chemical proteomics

(2011) Manfred Raida   CURRENT OPINION IN CHEMICAL BIOLOGY

Mdm2 associates with Ras effector NORE1 to induce the degradation of oncoprotein HIPK1

(2011) Deresa Lee et al.   EMBO REPORTS

Substantial Susceptibility of Chronic Lymphocytic Leukemia to BCL2 Inhibition: Results of a Phase I Study of Navitoclax in Patients With Relapsed or Refractory Disease

(2011) Andrew W. Roberts et al.   JOURNAL OF CLINICAL ONCOLOGY

The nucleoskeleton as a genome-associated dynamic 'network of networks'

(2011) Dan N. Simon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation

(2011) D P Mathiasen et al.   ONCOGENE

Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5

(2011) Dana V. Skarra et al.   PROTEOMICS

Structural basis of 14-3-3 protein functions

(2011) Tomas Obsil et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

An Atlas of Combinatorial Transcriptional Regulation in Mouse and Man

(2010) Timothy Ravasi et al.   CELL

Recent advances in charting protein–protein interaction: mass spectrometry-based approaches

(2010) Anne-Claude Gavin et al.   CURRENT OPINION IN BIOTECHNOLOGY

Crosslinking combined with mass spectrometry for structural proteomics

(2010) Evgeniy V. Petrotchenko et al.   MASS SPECTROMETRY REVIEWS

SAINT: probabilistic scoring of affinity purification–mass spectrometry data

(2010) Hyungwon Choi et al.   NATURE METHODS

Designing customized cell signalling circuits

(2010) Wendell A. Lim   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Post-translational modifications in signal integration

(2010) Yonathan Lissanu Deribe et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CIP2A mediates effects of bortezomib on phospho-Akt and apoptosis in hepatocellular carcinoma cells

(2010) K-F Chen et al.   ONCOGENE

The tandem affinity purification method: An efficient system for protein complex purification and protein interaction identification

(2010) Xiaoli Xu et al.   PROTEIN EXPRESSION AND PURIFICATION

A Global Protein Kinase and Phosphatase Interaction Network in Yeast

(2010) A. Breitkreutz et al.   SCIENCE

Assembly of ribosomes and spliceosomes: complex ribonucleoprotein machines

(2009) Jonathan P Staley et al.   CURRENT OPINION IN CELL BIOLOGY

RING Finger E3 Ubiquitin Ligases: Structure and Drug Discovery

(2009) Christos Chasapis et al.   CURRENT PHARMACEUTICAL DESIGN

MYC-Dependent Regulation and Prognostic Role of CIP2A in Gastric Cancer

(2009) Anchit Khanna et al.   JNCI-Journal of the National Cancer Institute

An integrated workflow for charting the human interaction proteome: insights into the PP2A system

(2009) Timo Glatter et al.   Molecular Systems Biology

Interactive learning: Lessons from two hybrids over two decades

(2009) Stanley Fields   PROTEOMICS

Mammalian two-hybrids come of age

(2009) Sam Lievens et al.   TRENDS IN BIOCHEMICAL SCIENCES

Scaffolds: interaction platforms for cellular signalling circuits

(2009) András Zeke et al.   TRENDS IN CELL BIOLOGY

Two-hybrid technologies in proteomics research

(2008) Bernhard Suter et al.   CURRENT OPINION IN BIOTECHNOLOGY

Mapping multiprotein complexes by affinity purification and mass spectrometry

(2008) Mark O Collins et al.   CURRENT OPINION IN BIOTECHNOLOGY

Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes

(2008) Laura Trinkle-Mulcahy et al.   JOURNAL OF CELL BIOLOGY

IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration

(2008) L. D. Johansen et al.   JOURNAL OF CELL SCIENCE

A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein

(2008) Marilyn Goudreault et al.   MOLECULAR & CELLULAR PROTEOMICS

Integrated network analysis platform for protein-protein interactions

(2008) Jianmin Wu et al.   NATURE METHODS

High-Quality Binary Protein Interaction Map of the Yeast Interactome Network

(2008) H. Yu et al.   SCIENCE

Multiple pathways regulated by the tumor suppressor PP2A in transformation

(2008) Jukka Westermarck et al.   TRENDS IN MOLECULAR MEDICINE

Study and selection of in vivo protein interactions by coupling bimolecular fluorescence complementation and flow cytometry

(2007) Montse Morell et al.   Nature Protocols