Metabolomics Coupled with Proteomics Advancing Drug Discovery toward More Agile Development of Targeted Combination Therapies

Urine Metabolomics Analysis for Biomarker Discovery and Detection of Jaundice Syndrome in Patients With Liver Disease

(2012) Xijun Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Future Perspectives of Chinese Medical Formulae: Chinmedomics as an Effector

(2012) Xijun Wang et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Rhein ameliorates fatty liver disease through negative energy balance, hepatic lipogenic regulation, and immunomodulation in diet-induced obese mice

(2011) Xiaoyan Sheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Pharmacokinetics screening for multi-components absorbed in the rat plasma after oral administration traditional Chinese medicine formula Yin-Chen-Hao-Tang by ultra performance liquid chromatography-electrospray ionization/quadrupole-time-of-flight mass spectrometry combined with pattern recognition methods

(2011) Xijun Wang et al.   ANALYST

Simultaneous in vivo RP-HPLC-DAD quantification of multiple-component and drug-drug interaction by pharmacokinetics, using 6,7-dimethylesculetin, geniposide and rhein as examples

(2011) Aihua Zhang et al.   BIOMEDICAL CHROMATOGRAPHY

An in vivo analysis of the therapeutic and synergistic properties of Chinese medicinal formula Yin-Chen-Hao-Tang based on its active constituents

(2011) Aihua Zhang et al.   FITOTERAPIA

Hepatoprotective effects of geniposide in a rat model of nonalcoholic steatohepatitis

(2011) Taotao Ma et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Targeted Mass Spectrometric Approach for Biomarker Discovery and Validation with Nonglycosylated Tryptic Peptides from N-linked Glycoproteins in Human Plasma

(2011) Ju Yeon Lee et al.   MOLECULAR & CELLULAR PROTEOMICS

A Serum Protein Profile Predictive of the Resistance to Neoadjuvant Chemotherapy in Advanced Breast Cancers

(2011) Seok-Won Hyung et al.   MOLECULAR & CELLULAR PROTEOMICS

Geniposide Induces the Expression of Heme Oxygenase-1 via PI3K/Nrf2-Signaling to Enhance the Antioxidant Capacity in Primary Hippocampal Neurons

(2010) Fei Yin et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Protective effects of coumarin and coumarin derivatives against carbon tetrachloride-induced acute hepatotoxicity in rats

(2010) Hakkı Murat Bilgin et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Identification of a new anti-LPS agent, geniposide, from Gardenia jasminoides Ellis, and its ability of direct binding and neutralization of lipopolysaccharide in vitro and in vivo

(2010) Xinchuan Zheng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

(2010) Min Gao et al.   NATURE

Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis

(2010) Ling Zhang et al.   NATURE

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

Molecular Targets for Diabetes Mellitus-associated Erectile Dysfunction

(2009) Elizabeth Yohannes et al.   MOLECULAR & CELLULAR PROTEOMICS

A systems biology understanding of the synergistic effects of arsenic sulfide and Imatinib in BCR/ABL-associated leukemia

(2009) Q.-Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-15 combined with an anti-CD40 antibody provides enhanced therapeutic efficacy for murine models of colon cancer

(2009) M. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acute promyelocytic leukemia: from highly fatal to highly curable

(2008) Z.-Y. Wang et al.   BLOOD

Metabolic urinary profiling of alcohol hepatotoxicity and intervention effects of Yin Chen Hao Tang in rats using ultra-performance liquid chromatography/electrospray ionization quadruple time-of-flight mass spectrometry

(2008) Xijun Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

15-Prostaglandin Dehydrogenase Expression Alone or in Combination with ACSM1 Defines a Subgroup of the Apocrine Molecular Subtype of Breast Carcinoma

(2008) Julio E. Celis et al.   MOLECULAR & CELLULAR PROTEOMICS

Phenols from the Roots ofRheum palmatumAttenuate Chemotaxis in Rat Hepatic Stellate Cells

(2008) Yun-Lian Lin et al.   PLANTA MEDICA

The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice

(2008) F. Pibiri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: Blockade of compensatory renin increase

(2008) Z. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia

(2008) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of the constituents in the rat plasma after oral administration of Yin Chen Hao Tang by UPLC/Q-TOF-MS/MS

(2007) Xijun Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Quality evaluation of Yin Chen Hao Tang extract based on fingerprint chromatogram and simultaneous determination of five bioactive constituents

(2007) Xijun Wang et al.   JOURNAL OF SEPARATION SCIENCE