Secretomic Analysis Identifies Alpha-1 Antitrypsin (A1AT) as a Required Protein in Cancer Cell Migration, Invasion, and Pericellular Fibronectin Assembly for Facilitating Lung Colonization of Lung Adenocarcinoma Cells

Biomarkers for the lung cancer diagnosis and their advances in proteomics

(2011) Hye-Jin Sung et al.   BMB Reports

An Informatics-assisted Label-free Approach for Personalized Tissue Membrane Proteomics: Case Study on Colorectal Cancer

(2011) Chia-Li Han et al.   MOLECULAR & CELLULAR PROTEOMICS

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Oxidation of Z α1-Antitrypsin by Cigarette Smoke Induces Polymerization

(2010) Sam Alam et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2010) G. D'Addario et al.   ANNALS OF ONCOLOGY

TWIST activation by hypoxia inducible factor-1 (HIF-1): Implications in metastasis and development

(2010) Muh-Hwa Yang et al.   CELL CYCLE

Chymase Inhibition Prevents Fibronectin and Myofibrillar Loss and Improves Cardiomyocyte Function and LV Torsion Angle in Dogs With Isolated Mitral Regurgitation

(2010) Betty Pat et al.   CIRCULATION

Protease inhibitor SERPINA1 expression in epithelial ovarian cancer

(2010) Karine Normandin et al.   CLINICAL & EXPERIMENTAL METASTASIS

Genetic Variants of α 1-Antitrypsin

(2010) Parveen Salahuddin   CURRENT PROTEIN & PEPTIDE SCIENCE

Quantitative Secretome Analysis Reveals that COL6A1 is a Metastasis-Associated Protein Using Stacking Gel-Aided Purification Combined with iTRAQ Labeling

(2010) Kuo-Hsun Chiu et al.   JOURNAL OF PROTEOME RESEARCH

Exosomes: Extracellular organelles important in intercellular communication

(2010) Suresh Mathivanan et al.   Journal of Proteomics

Candidate Serological Biomarkers for Cancer Identified from the Secretomes of 23 Cancer Cell Lines and the Human Protein Atlas

(2010) Chih-Ching Wu et al.   MOLECULAR & CELLULAR PROTEOMICS

Hypoxic Tumor Cell Modulates Its Microenvironment to Enhance Angiogenic and Metastatic Potential by Secretion of Proteins and Exosomes

(2010) Jung Eun Park et al.   MOLECULAR & CELLULAR PROTEOMICS

Protein kinase Cɛ mediates Stat3Ser727 phosphorylation, Stat3-regulated gene expression and cell invasion in various human cancer cell lines through integration with MAPK cascade (RAF-1, MEK1/2 and ERK1/2)

(2010) M H Aziz et al.   ONCOGENE

Linkage Specific Fucosylation of Alpha-1-Antitrypsin in Liver Cirrhosis and Cancer Patients: Implications for a Biomarker of Hepatocellular Carcinoma

(2010) Mary Ann Comunale et al.   PLoS One

Quantitative proteomics approach for identifying protein-drug interactions in complex mixtures using protein stability measurements

(2010) G. M. West et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes in Tumour Immunity

(2009) Aled Clayton et al.   Current Oncology

Exosomes: proteomic insights and diagnostic potential

(2009) Richard J Simpson et al.   Expert Review of Proteomics

Epitope analysis of the rat dipeptidyl peptidase IV monoclonal antibody 6A3 that blocks pericellular fibronectin-mediated cancer cell adhesion

(2009) Ting-Ting Hung et al.   FEBS Journal

Crystallographic and Cellular Characterisation of Two Mechanisms Stabilising the Native Fold of α1-Antitrypsin: Implications for Disease and Drug Design

(2009) Bibek Gooptu et al.   JOURNAL OF MOLECULAR BIOLOGY

Cell Secretome Analysis Using Hollow Fiber Culture System Leads to the Discovery of CLIC1 Protein as a Novel Plasma Marker for Nasopharyngeal Carcinoma

(2009) Ying-Hwa Chang et al.   JOURNAL OF PROTEOME RESEARCH

Identification of Serum Biomarkers for Colorectal Cancer Metastasis Using a Differential Secretome Approach

(2009) Hua Xue et al.   JOURNAL OF PROTEOME RESEARCH

Alterations in cellular proteome and secretome upon differentiation from monocyte to macrophage by treatment with phorbol myristate acetate: Insights into biological processes

(2009) Kitisak Sintiprungrat et al.   Journal of Proteomics

Proteomics Analysis of A33 Immunoaffinity-purified Exosomes Released from the Human Colon Tumor Cell Line LIM1215 Reveals a Tissue-specific Protein Signature

(2009) Suresh Mathivanan et al.   MOLECULAR & CELLULAR PROTEOMICS

Display of Cell Surface Sites for Fibronectin Assembly Is Modulated by Cell Adherence to 1F3 and C-Terminal Modules of Fibronectin

(2009) Jielin Xu et al.   PLoS One

ExoCarta: A compendium of exosomal proteins and RNA

(2009) Suresh Mathivanan et al.   PROTEOMICS

Alpha1-Antitrypsin Deficiency Carriers, Tobacco Smoke, Chronic Obstructive Pulmonary Disease, and Lung Cancer Risk

(2008) Ping Yang   ARCHIVES OF INTERNAL MEDICINE

Active Caspase-1 Is a Regulator of Unconventional Protein Secretion

(2008) Martin Keller et al.   CELL

Oncogenic BRAF Induces Senescence and Apoptosis through Pathways Mediated by the Secreted Protein IGFBP7

(2008) Narendra Wajapeyee et al.   CELL

EMT and MET in carcinoma—clinical observations, regulatory pathways and new models

(2008) Erik W. Thompson et al.   CLINICAL & EXPERIMENTAL METASTASIS

Predictors of Survival in Patients With Bone Metastasis of Lung Cancer

(2008) Hideshi Sugiura et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

(2008) Jing Yang et al.   DEVELOPMENTAL CELL

Protein Kinase Cϵ Mediates Polymeric Fibronectin Assembly on the Surface of Blood-borne Rat Breast Cancer Cells to Promote Pulmonary Metastasis

(2008) Lynn Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells

(2008) Nathalie Scamuffa et al.   JOURNAL OF CLINICAL INVESTIGATION

Proteomics Analysis of Nasopharyngeal Carcinoma Cell Secretome Using a Hollow Fiber Culture System and Mass Spectrometry

(2008) Hsin-Yi Wu et al.   JOURNAL OF PROTEOME RESEARCH

Epithelial-to-Mesenchymal Transition Is Important to Metastasis, But Questions Remain

(2008) K. Garber   JNCI-Journal of the National Cancer Institute