Quantitative Proteomics with siRNA Screening Identifies Novel Mechanisms of Trastuzumab Resistance in HER2 Amplified Breast Cancers

p95HER2 and Breast Cancer

(2011) J. Arribas et al.   CANCER RESEARCH

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Initial genome sequencing and analysis of multiple myeloma

(2011) Michael A. Chapman et al.   NATURE

Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways

(2011) Siyuan Zhang et al.   NATURE MEDICINE

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis

(2011) H. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2+breast cancer patients

(2011) Maurizio Scaltriti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase

(2011) J. T. Garrett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VHLloss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKCδ-driven migration

(2011) Olga V. Razorenova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis

(2010) Xiaofeng Zhao et al.   ADVANCED DRUG DELIVERY REVIEWS

Recombinant Human Erythropoietin Antagonizes Trastuzumab Treatment of Breast Cancer Cells via Jak2-Mediated Src Activation and PTEN Inactivation

(2010) Ke Liang et al.   CANCER CELL

Mechanisms of resistance to anti-human epidermal growth factor receptor 2 agents in breast cancer

(2010) Toru Mukohara   CANCER SCIENCE

Targeting the transforming growth factor-β signalling pathway in metastatic cancer

(2010) Manav Korpal et al.   EUROPEAN JOURNAL OF CANCER

Phase II Study of the Antibody Drug Conjugate Trastuzumab-DM1 for the Treatment of Human Epidermal Growth Factor Receptor 2 (HER2) –Positive Breast Cancer After Prior HER2-Directed Therapy

(2010) Howard A. Burris et al.   JOURNAL OF CLINICAL ONCOLOGY

Quantitative Analysis of HGF and EGF-Dependent Phosphotyrosine Signaling Networks

(2010) Dean E. Hammond et al.   JOURNAL OF PROTEOME RESEARCH

Phosphorylation of Trask by Src Kinases Inhibits Integrin Clustering and Functions in Exclusion with Focal Adhesion Signaling

(2010) D. S. Spassov et al.   MOLECULAR AND CELLULAR BIOLOGY

Elevation of Receptor Tyrosine Kinase EphA2 Mediates Resistance to Trastuzumab Therapy

(2009) G. Zhuang et al.   CANCER RESEARCH

An Integrated Approach of Differential Mass Spectrometry and Gene Ontology Analysis Identified Novel Proteins Regulating Neuronal Differentiation and Survival

(2009) Daiki Kobayashi et al.   MOLECULAR & CELLULAR PROTEOMICS

Genetic Alterations and Oncogenic Pathways Associated with Breast Cancer Subtypes

(2009) X. Hu et al.   MOLECULAR CANCER RESEARCH

Molecular Profiling of Breast Cancer Cell Lines Defines Relevant Tumor Models and Provides a Resource for Cancer Gene Discovery

(2009) Jessica Kao et al.   PLoS One

Cell-Specific Information Processing in Segregating Populations of Eph Receptor Ephrin-Expressing Cells

(2009) C. Jorgensen et al.   SCIENCE

Detection of circulating cancer cells in lung cancer patients with a panel of marker genes

(2008) Lei Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ErbB4/HER4: Role in Mammary Gland Development, Differentiation and Growth Inhibition

(2008) Rebecca S. Muraoka-Cook et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Role of ErbB4 in Breast Cancer

(2008) Maria Sundvall et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Screening for EphB Signaling Effectors Using SILAC with a Linear Ion Trap-Orbitrap Mass Spectrometer

(2008) Guoan Zhang et al.   JOURNAL OF PROTEOME RESEARCH

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Dissection of the insulin signaling pathway via quantitative phosphoproteomics

(2008) M. Kruger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly Robust, Automated, and Sensitive Online TiO2-Based Phosphoproteomics Applied To Study Endogenous Phosphorylation inDrosophila melanogaster

(2007) Martijn W. H. Pinkse et al.   JOURNAL OF PROTEOME RESEARCH