Article
Rheumatology
Elena Borlandelli, Jacopo Ciaffi, Gianluca Festuccia, Giancarlo Facchini, Marco Miceli, Veronica Brusi, Luana Mancarella, Lucia Lisi, Alberto Di Martino, Cesare Faldini, Riccardo Meliconi, Francesco Ursini
Summary: Osteitis condensans ilii (OCI) is a benign condition characterized by triangular sclerosis of the iliac bone, with a prevalence of around 1.0% in the general population, more commonly seen in women. There were no significant differences in clinical and radiographic features between patients with OCI and women without the condition.
CLINICAL RHEUMATOLOGY
(2022)
Article
Medicine, General & Internal
Maximilian Muellner, Katharina Ziegeler, Torsten Diekhoff, Henryk Haffer, Friederike Schoemig, Vincent Justus Leopold, Matthias Pumberger, Friedemann Goehler
Summary: This study found a higher prevalence of osteitis condensans ilii (OCI) in patients with developmental dysplasia of the hip (DDH) compared to the general population, and BMI was shown to have an influence on the occurrence of OCI. OCI may be attributable to altered mechanical loading of the hip and sacroiliac joints. Clinicians should be aware of the common occurrence of OCI in DDH patients and its potential association with low back pain, lateral hip pain, and nonspecific hip or thigh pain.
Article
Rheumatology
Alexandre Terrier, Olivier Fakih, Mickael Chouk, Clement Prati, Daniel Wendling, Sebastien Aubry, Frank Verhoeven
Summary: This study aimed to compare the SBAC-SI differences in AS, OCI, and DISH. The results showed that SBAC-SI was significantly higher in the OCI group compared to the AS group, which could help distinguish between these two diseases. In AS, the disease duration was negatively correlated with SBAC-SI, and HLA B27 was associated with lower SBAC-SI.
Article
Medicine, General & Internal
Henry Egbuchiem, Nkemputaife Onyechi, Onoja-Frederick Okwori, Akpezi Oshobe
Summary: Osteitis condensans ilii (OCI), an uncommon cause of chronic back pain, can often be misdiagnosed and lead to unnecessary diagnostic tests and increased healthcare costs. We present a case of OCI presenting as unusual chronic lower back pain in a postmenopausal female to enhance awareness of this disease.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Medicine, General & Internal
Krishna Bashyal, Kamal Dhungana, Deepesh Yadav, Dilli Ram Poudel, Calvin Ghimire, Shravya Balmuri
Summary: OCI is an underrecognized condition that causes low back pain, primarily affecting the iliac bones while sparing the sacroiliac joint. We present a case of a 48-year-old female who was diagnosed with OCI after experiencing back symptoms for 4 years.
CLINICAL CASE REPORTS
(2023)
Article
Medicine, Research & Experimental
Xinghua Zhou, Ruirui Sun, Ying Zhang
Summary: OCI has a high prevalence in women during the postpartum period. ESWT is an effective and safe treatment method for OCI, resulting in higher patient satisfaction rates.
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Alberto Ruffilli, Simona Neri, Marco Manzetti, Francesca Barile, Giovanni Viroli, Matteo Traversari, Elisa Assirelli, Fabio Vita, Giuseppe Geraci, Cesare Faldini
Summary: Low back pain (LBP) is a common cause of pain and disability, but current treatments often fail to provide sufficient relief. Identifying reliable biomarkers associated with LBP, such as epigenetic factors, could improve clinical practice. This review examined the literature on epigenetic factors and found promising markers that could significantly impact disease management and treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Clinical Neurology
Zeynab Alshelh, Ludovica Brusaferri, Atreyi Saha, Erin Morrissey, Paulina Knight, Minhae Kim, Yi Zhang, Jacob M. Hooker, Daniel Albrecht, Angel Torrado-Carvajal, Michael S. Placzek, Oluwaseun Akeju, Julie Price, Robert R. Edwards, Jeungchan Lee, Roberta Sclocco, Ciprian Catana, Vitaly Napadow, Marco L. Loggia
Summary: This study suggests that patients with different chronic pain conditions exhibit neuroinflammation, which is accompanied by neurophysiological changes and correlates with clinical presentation. These findings contribute to the subtyping of distinct pain syndromes and provide potential targets for precision medicine.
Review
Medicine, General & Internal
Vanina Nicol, Claire Verdaguer, Camille Daste, Helene Bisseriex, Eric Lapeyre, Marie-Martine Lefevre-Colau, Francois Rannou, Alexandra Roeren, Julia Facione, Christelle Nguyen
Summary: Chronic low back pain is a significant burden on individuals and society. International guidelines recommend using flags to identify the risk of chronicity and advocate for non-pharmacological treatments as the mainstay of management for non-specific chronic low back pain.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Daniel L. Belavy, Ashish D. Diwan, Jon Ford, Clint T. Miller, Andrew J. Hahne, Niamh Mundell, Scott Tagliaferri, Steven Bowe, Hugo Pedder, Tobias Saueressig, Xiaohui Zhao, Xiaolong Chen, Arun Prasad Balasundaram, Nitin Kumar Arora, Patrick J. Owen
Summary: This study aims to evaluate the effectiveness of various treatments for chronic low back pain disorders (CLBDs) in patients, including acupuncture, education, exercise, pharmacotherapy, and more. The research includes network meta-analysis to assess the relative effectiveness of these treatments.
Review
Medicine, General & Internal
Zugui Wu, Yi Wang, Xiangling Ye, Zehua Chen, Rui Zhou, Zixuan Ye, Jinyou Huang, Yue Zhu, Guocai Chen, Xuemeng Xu
Summary: This study systematically evaluated the efficacy of myofascial release in the treatment of chronic low back pain. The results showed that myofascial release significantly improved pain and physical function in patients with CLBP, but did not have significant effects on quality of life, balance function, pain pressure-threshold, trunk mobility, and mental health.
FRONTIERS IN MEDICINE
(2021)
Article
Biotechnology & Applied Microbiology
Ronen Cozacov, Amir Minerbi, May Haddad, Simon Vulfsons
Summary: Muscles and fascia both show sensitization in individuals with myofascial low back pain, but muscles are more sensitized than fascia.
BIOENGINEERING-BASEL
(2022)
Review
Medicine, General & Internal
Nebojsa Nick Knezevic, Kenneth D. Candido, Johan W. S. Vlaeyen, Jan Van Zundert, Steven P. Cohen
Summary: Low back pain encompasses various types of pain, with diagnostic and therapeutic methods controversial, requiring a comprehensive approach considering biological, psychological, and social factors. Improvement in diagnostic accuracy, treatment algorithms, and multimodal interdisciplinary treatment are essential.
Review
Medicine, General & Internal
Gloria Gonzalez-Medina, Veronica Perez-Cabezas, Carmen Ruiz-Molinero, Gema Chamorro-Moriana, Jose Jesus Jimenez-Rejano, Alejandro Galan-Mercant
Summary: The meta-analysis demonstrated that global postural re-education (GPR) program is effective in reducing pain and improving function in patients with persistent chronic low back pain, with strong evidence support.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Clinical Neurology
Patricia M. Herman, Nabeel Qureshi, Susan D. Arick, Maria O. Edelen, Ron D. Hays, Anthony Rodriguez, Rebecca L. Weir, Ian D. Coulter
Summary: The definition of chronic low back pain (CLBP) varies among researchers and individuals. Recent RCTs mainly define CLBP by duration, while individuals often define it by frequency. Only about 6% of recent RCTs followed the RTF definition. Healthcare provider diagnosis is not a defining characteristic for CLBP. Researchers should be aware of these variations to better select study criteria.