Oxidative DNA damage drives carcinogenesis in MUTYH-associated-polyposis by specific mutations of mitochondrial and MAPK genes

Intra-tumoral Heterogeneity ofKRASandBRAFMutation Status in Patients with Advanced Colorectal Cancer (aCRC) and Cost-Effectiveness of Multiple Sample Testing

(2015) Susan D. Richman et al.   Analytical Cellular Pathology

Editorial: Sessile Serrated Adenomas and Their Pit Patterns: We Must First See the Forest Through the Trees

(2012) Carol A Burke et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Concordance in KRAS and BRAF mutations in endoscopic biopsy samples and resection specimens of colorectal adenocarcinoma

(2012) L.C. Krol et al.   EUROPEAN JOURNAL OF CANCER

KRAS and BRAF Mutation Analysis in Routine Molecular Diagnostics

(2012) Daniëlle A.M. Heideman et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Evidence for accelerated colorectal adenoma–carcinoma progression inMUTYH-associated polyposis?

(2011) M H Nieuwenhuis et al.   GUT

Uncovering the Profile of Somatic mtDNA Mutations in Chinese Colorectal Cancer Patients

(2011) Cheng-Ye Wang et al.   PLoS One

Selection of cancer cells with repressed mitochondria triggers colon cancer progression

(2010) María Sánchez-Aragó et al.   CARCINOGENESIS

Association of KRAS p.G13D Mutation With Outcome in Patients With Chemotherapy-Refractory Metastatic Colorectal Cancer Treated With Cetuximab

(2010) Wendy De Roock et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Oncogenic KRAS is not necessary for Wnt signalling activation in APC-associated FAP adenomas

(2010) Antònia Obrador-Hevia et al.   JOURNAL OF PATHOLOGY

Cellular senescence: unravelling complexity

(2009) João F. Passos et al.   AGE

MUTYH-associated polyposis carcinomas frequently lose HLA class I expression-a common event amongst DNA-repair-deficient colorectal cancers

(2009) Noel FCC de Miranda et al.   JOURNAL OF PATHOLOGY

Mitochondrial Dysfunction Contributes to Oncogene-Induced Senescence

(2009) O. Moiseeva et al.   MOLECULAR AND CELLULAR BIOLOGY

Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells

(2009) J. Yun et al.   SCIENCE

Identification of Patients with (Atypical) MUTYH-Associated Polyposis by KRAS2 c.34G > T Prescreening Followed by MUTYH Hotspot Analysis in Formalin-Fixed Paraffin-Embedded Tissue

(2008) M. van Puijenbroek et al.   CLINICAL CANCER RESEARCH

Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs

(2008) Sugako Oka et al.   EMBO JOURNAL

Hyperplastic Polyps and Sessile Serrated Adenomas as a Phenotypic Expression of MYH-Associated Polyposis

(2008) Karam S. Boparai et al.   GASTROENTEROLOGY

Analysis of MUTYH Genotypes and Colorectal Phenotypes in Patients With MUTYH-Associated Polyposis

(2008) Maartje Nielsen et al.   GASTROENTEROLOGY

In melanocytic lesions the fraction of BRAFV600E alleles is associated with sun exposure but unrelated to ERK phosphorylation

(2008) Tiziana Venesio et al.   MODERN PATHOLOGY