Genetic and epigenetic changes in lung carcinoma and their clinical implications

Epidermal growth factor receptor inhibition in lung cancer: the evolving role of individualized therapy

(2010) Adi F. Gazdar   CANCER AND METASTASIS REVIEWS

Lung cancer: From single-gene methylation to methylome profiling

(2010) Gerwin Heller et al.   CANCER AND METASTASIS REVIEWS

MicroRNA-519c Suppresses Hypoxia-Inducible Factor-1α Expression and Tumor Angiogenesis

(2010) Shih-Ting Cha et al.   CANCER RESEARCH

Accurate Classification of Non-Small Cell Lung Carcinoma Using a Novel MicroRNA-Based Approach

(2010) J. A. Bishop et al.   CLINICAL CANCER RESEARCH

MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors

(2010) Xi Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients

(2010) Ruo-Kai Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

Serum MicroRNA Signatures Identified in a Genome-Wide Serum MicroRNA Expression Profiling Predict Survival of Non–Small-Cell Lung Cancer

(2010) Zhibin Hu et al.   JOURNAL OF CLINICAL ONCOLOGY

Using Whole Genome Amplification (WGA) of Low-Volume Biopsies to Assess the Prognostic Role of EGFR, KRAS, p53, and CMET Mutations in Advanced-Stage Non-small Cell Lung Cancer (NSCLC)

(2010) Elaine H. Lim et al.   Journal of Thoracic Oncology

Prognostic Implication of EGFR, KRAS, and TP53 Gene Mutations in a Large Cohort of Japanese Patients with Surgically Treated Lung Adenocarcinoma

(2010) Takayuki Kosaka et al.   Journal of Thoracic Oncology

Global Levels of Histone Modifications Predict Prognosis in Different Cancers

(2009) David B. Seligson et al.   AMERICAN JOURNAL OF PATHOLOGY

EML4-ALK Rearrangement in Non-Small Cell Lung Cancer and Non-Tumor Lung Tissues

(2009) Maria Paola Martelli et al.   AMERICAN JOURNAL OF PATHOLOGY

Clinicopathologic Features of Non-Small-Cell Lung Cancer with EML4–ALK Fusion Gene

(2009) Tsuyoshi Takahashi et al.   ANNALS OF SURGICAL ONCOLOGY

MicroRNA 133B targets pro-survival molecules MCL-1 and BCL2L2 in lung cancer

(2009) Melissa Crawford et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miR-126 inhibits non-small cell lung cancer cells proliferation by targeting EGFL7

(2009) Yanqin Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA Classifiers for Predicting Prognosis of Squamous Cell Lung Cancer

(2009) M. Raponi et al.   CANCER RESEARCH

miR-15a and miR-16 Are Implicated in Cell Cycle Regulation in a Rb-Dependent Manner and Are Frequently Deleted or Down-regulated in Non–Small Cell Lung Cancer

(2009) Nora Bandi et al.   CANCER RESEARCH

Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers

(2009) Mathewos Tessema et al.   CARCINOGENESIS

miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer

(2009) Elena Gallardo et al.   CARCINOGENESIS

Epigenetics in cancer

(2009) S. Sharma et al.   CARCINOGENESIS

Genomic Profiles Associated with Early Micrometastasis in Lung Cancer: Relevance of 4q Deletion

(2009) M. Wrage et al.   CLINICAL CANCER RESEARCH

Unique Clinicopathologic Features Characterize ALK-Rearranged Lung Adenocarcinoma in the Western Population

(2009) S. J. Rodig et al.   CLINICAL CANCER RESEARCH

Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancers Dependent on the Epidermal Growth Factor Receptor Pathway

(2009) Kim-Son H. Nguyen et al.   Clinical Lung Cancer

Let-7a elevates p21WAF1levels by targeting of NIRF and suppresses the growth of A549 lung cancer cells

(2009) Xiaoyan He et al.   FEBS LETTERS

Effect of IFN-β on human glioma cell lines with temozolomide resistance

(2009) Yoshino   INTERNATIONAL JOURNAL OF ONCOLOGY

RASSF1A, APC, ESR1, ABCB1 and HOXC9, but not p16INK4A, DAPK1, PTEN and MT1G genes were frequently methylated in the stage I non-small cell lung cancer in China

(2009) Qiang Lin et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Clinical Features and Outcome of Patients With Non–Small-Cell Lung Cancer Who Harbor EML4-ALK

(2009) Alice T. Shaw et al.   JOURNAL OF CLINICAL ONCOLOGY

Diagnostic Assay Based on hsa-miR-205 Expression Distinguishes Squamous From Nonsquamous Non–Small-Cell Lung Carcinoma

(2009) Danit Lebanony et al.   JOURNAL OF CLINICAL ONCOLOGY

MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo

(2009) Bo Liu et al.   LUNG CANCER

Altered miRNA expression in sputum for diagnosis of non-small cell lung cancer

(2009) Ying Xie et al.   LUNG CANCER

MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines

(2008) M. Crawford et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DLEC1 and MLH1 promoter methylation are associated with poor prognosis in non-small cell lung carcinoma

(2008) T J Seng et al.   BRITISH JOURNAL OF CANCER

Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer

(2008) J Xing et al.   BRITISH JOURNAL OF CANCER

MicroRNA Signature Predicts Survival and Relapse in Lung Cancer

(2008) Sung-Liang Yu et al.   CANCER CELL

HDAC family: What are the cancer relevant targets?

(2008) Olaf Witt et al.   CANCER LETTERS

Genomic Alterations of Anaplastic Lymphoma Kinase May Sensitize Tumors to Anaplastic Lymphoma Kinase Inhibitors

(2008) U. McDermott et al.   CANCER RESEARCH

Identification of Novel Isoforms of the EML4-ALK Transforming Gene in Non-Small Cell Lung Cancer

(2008) Y. L. Choi et al.   CANCER RESEARCH

Quantitative Analysis of DNA Methylation Profiles in Lung Cancer Identifies Aberrant DNA Methylation of Specific Genes and Its Association with Gender and Cancer Risk Factors

(2008) T. Vaissiere et al.   CANCER RESEARCH

Frequency and Distinctive Spectrum of KRAS Mutations in Never Smokers with Lung Adenocarcinoma

(2008) G. J. Riely et al.   CLINICAL CANCER RESEARCH

Prognostic Value of Mature MicroRNA-21 and MicroRNA-205 Overexpression in Non-Small Cell Lung Cancer by Quantitative Real-Time RT-PCR

(2008) A. Markou et al.   CLINICAL CHEMISTRY

FHIT and p53 Status and Response to Platinum-Based Treatment in Advanced Non-Small Cell Lung Cancer

(2008) D. Cortinovis et al.   CURRENT CANCER DRUG TARGETS

ErbBs in lung cancer

(2008) Sreenath V. Sharma et al.   EXPERIMENTAL CELL RESEARCH

MicroRNA-183 regulates Ezrin expression in lung cancer cells

(2008) Guofu Wang et al.   FEBS LETTERS

Role ofKRASandEGFRAs Biomarkers of Response to Erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21

(2008) Chang-Qi Zhu et al.   JOURNAL OF CLINICAL ONCOLOGY

3p22.1 and 10q22.3 Deletions Detected by Fluorescence In Situ Hybridization (FISH): A Potential New Tool for Early Detection of Non-small Cell Lung Cancer (NSCLC)

(2008) Sai Yendamuri et al.   Journal of Thoracic Oncology

EML4-ALK Fusion Is Linked to Histological Characteristics in a Subset of Lung Cancers

(2008) Kentaro Inamura et al.   Journal of Thoracic Oncology

EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas

(2008) Kazuya Shinmura et al.   LUNG CANCER

DNA Methylation Markers and Early Recurrence in Stage I Lung Cancer

(2008) Malcolm V. Brock et al.   NEW ENGLAND JOURNAL OF MEDICINE

LKB1; linking cell structure and tumor suppression

(2008) A F Hezel et al.   ONCOGENE

The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development

(2008) T. V. Sharp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

(2008) C.-H. Yun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA