Journal
MITOCHONDRION
Volume 12, Issue 5, Pages 483-491Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.mito.2012.07.105
Keywords
Mitochondrial genomes; Repeats Palindromes; Gene conversion; Genomics Bioinformatics
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All complete or nearly complete mitochondrial genomes of Metazoa (2819) have been subject to bioinformatic analysis to investigate the distribution and features of repeated and palinclromic sequences. Repeats are ubiquitous, with 29.9% of genomes containing at least one and 1.95% of total genome length being repeated. Repeat boundaries were tested for the presence of secondary structure motifs, consensus sequences or small repeats, features generally reported as associated with duplications. No significant relationship was detected, suggesting the non ubiquitousness of such features. A mechanism related to gene conversion is proposed to explain the origin of small interspersed repeats. (C) 2012 Elsevier B.V. and Mitochondria Research Society. All rights reserved.
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