Article
Cell Biology
Seyed Amirhossein Tabatabaei Dakhili, Kunyan Yang, Cassandra A. A. Locatelli, Christina T. Saed, Amanda A. Greenwell, Jordan S. F. Chan, Jadin J. Chahade, Jared Scharff, Shahad Al-Imarah, Farah Eaton, Peter A. Crawford, Keshav Gopal, Erin E. Mulvihill, John R. Ussher
Summary: Acute elevations in circulating ketones improve glucose tolerance in obesity, independent of muscle ketone oxidation.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
(2023)
Article
Health Care Sciences & Services
Andrea Foppiani, Fabiana Ciciriello, Arianna Bisogno, Silvia Bricchi, Carla Colombo, Federico Alghisi, Vincenzina Lucidi, Maria Ausilia Catena, Mariacristina Lucanto, Andrea Mari, Giorgio Bedogni, Alberto Battezzati
Summary: This study aimed to describe the distribution and provide reference quartiles of OGTT-related variables in the Italian cystic fibrosis population. The results showed the deterioration of glucose tolerance and insulin secretion with age according to sex and pancreatic insufficiency, highlighting a deviation from linearity for patients 35 years of age.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Endocrinology & Metabolism
Shihao Hu, Yuzhi Lu, Andrea Tura, Giovanni Pacini, David Z. D'Argenio
Summary: Glucose effectiveness, the ability of glucose to regulate glucose utilization and production in the body, plays a significant role in maintaining normal blood sugar levels. Hierarchical statistical analysis revealed that individuals with type 2 diabetes had a decreased glucose effectiveness compared to non-diabetic individuals. This finding suggests that glucose effectiveness could be a potential marker for glucose metabolism disorders and a target for diabetes treatment.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Nutrition & Dietetics
Mari Lahelma, Panu K. Luukkonen, Sami Qadri, Noora Ahlholm, Susanna Lallukka-Bruck, Kimmo Porthan, Anne Juuti, Henna Sammalkorpi, Anne K. Penttila, Johanna Arola, Marju Orho-Melander, Hannele Yki-Jarvinen
Summary: Detailed assessment of lifestyle factors, in addition to physical, biochemical and genetic factors, helps identify obese patients with non-alcoholic fatty liver disease (NAFLD) fibrosis more accurately. This comprehensive approach was shown to be more effective in predicting NAFLD fibrosis than evaluating lifestyle, physical, biochemical, or genetic factors alone.
Article
Endocrinology & Metabolism
Tao Yuan, Shuoning Song, Tianyi Zhao, Yanbei Duo, Shihan Wang, Junxiang Gao, Shixuan Liu, Yingyue Dong, Rui Li, Yong Fu, Weigang Zhao
Summary: The study identified two different patterns of FPIS among subjects with normal glucose tolerance, indicating that individuals with later time to glucose peak during FPIS may have a lower risk of developing type 2 diabetes in the future.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Marcelina Sperling, Teresa Grzelak, Marta Pelczynska, Pawel Bogdanski, Dorota Formanowicz, Krystyna Czyzewska
Summary: Omentin-1 levels are associated with central obesity and abnormal glucose tolerance, with lower levels found in obese patients and men with abnormal glucose tolerance. Gender, tissue insulin sensitivity, WHR, and body fat amount all have significant effects on serum omentin-1 concentration. High omentin-1 levels in men with obesity and normal glucose tolerance suggest a protective effect against metabolic disorders associated with obesity in males.
Article
Environmental Sciences
Pengfei Gong, Danielle Bailbe, Stefania Tolu, Gaelle Pommier, Junjun Liu, Jamileh Movassat
Summary: Since the restricted use of BPA due to its endocrine disruptor properties, BPS has been widely used as a substitute. However, BPS has similar effects on metabolic health as BPA. Previous studies have documented the effects of maternal exposure to BPA and BPS on offspring, but the impact of preconceptional paternal exposure to BPS remains unexplored. This study showed that preconceptional paternal exposure to BPS had non-monotonic and sex-specific effects on the metabolic health of offspring, suggesting that BPS is not a safe substitute for BPA regarding the inter-generational transmission of metabolic disorders through the paternal lineage.
Article
Environmental Sciences
Qiang Ma, Houguo Xu, Samwel Mchele Limbu, Yuliang Wei, Mengqing Liang
Summary: In this study, the ability of fish to utilize carbohydrates was evaluated by intraperitoneal injection or oral administration of glucose or fructose to tiger puffer and turbot. The results showed that glucose and fructose stimulated insulin secretion and improved hypoxia tolerance in the two marine fishes.
FRONTIERS IN MARINE SCIENCE
(2023)
Article
Medicine, Research & Experimental
Teresa Mezza, Pietro Manuel Ferraro, Gianfranco Di Giuseppe, Simona Moffa, Chiara M. A. Cefalo, Francesca Cinti, Flavia Impronta, Umberto Capece, Giuseppe Quero, Alfredo Pontecorvi, Andrea Mari, Sergio Alfieri, Andrea Giaccari
Summary: This study aimed to verify the acute effect of reduced beta cell mass on the development of hyperglycemia. The research found that reduced first-phase insulin secretion and glucose sensitivity were predictors of eventual development of impaired glucose tolerance and diabetes. Thus, these functional alterations may play a key role in the pathogenesis of type 2 diabetes (T2DM).
JOURNAL OF CLINICAL INVESTIGATION
(2021)
Article
Psychology, Biological
John I. Glendinning, Niki Williams
Summary: This study examined the effects of ad lib consumption of glucose and high-fructose syrups on glucose tolerance in mice. The results showed that glucose consumption improved glucose tolerance, while high-fructose consumption did not. Glucose consumption also increased cephalic-phase insulin release and insulin sensitivity. These findings suggest that mice can adapt metabolically to high glucose diets by upregulating components of the insulin response system.
PHYSIOLOGY & BEHAVIOR
(2022)
Article
Agriculture, Dairy & Animal Science
M. Duplessis, C. L. Girard
Summary: The study aimed to evaluate the glucose and insulin metabolism in cows with supplementation of biotin, folic acid, and vitamin B-12 during the transition period. Results showed that cows receiving a biotin supplement had reduced insulin sensitivity in early lactation, while cows supplemented with folic acid and vitamin B-12 had a faster insulin response, though this did not lead to further improvements after a glucose challenge.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
T. T. Yohe, H. Berends, L. N. Leal, J. N. Wilms, M. A. Steele, J. Martin-Tereso
Summary: This study aimed to investigate the effect of increasing replacement of lactose by fat on growth performance, nutrient digestibility, and glucose/insulin sensitivity in rearing calves. The results showed that altering the lactose:fat ratio in calf milk replacer did not significantly affect growth performance, but had minor effects on nutrient metabolism.
Article
Biochemistry & Molecular Biology
Dimitrios Voudouris, Maria Horianopoulou, Zoi Apostolopoulou, Costas Chryssanthopoulos, Mari Bardopoulou, Maria Maridaki, Theodoros Vassilakopoulos, Michael Koutsilieris, Anastassios Philippou
Summary: Short-term daily combined exercise can improve hepatic steatosis and central adiposity indices in patients with NAFLD, independent of weight loss.
Article
Biochemistry & Molecular Biology
Christopher P. Hedges, Jordi Boix, Jagdish K. Jaiswal, Bhoopika Shetty, Peter R. Shepherd, Troy L. Merry
Summary: BYL719 delivered through diet effectively suppresses insulin signaling and maintains long-term efficacy without affecting food intake and other physiological indicators.
Article
Medicine, Research & Experimental
Benedikt Dietz, Juergen Machann, Vaibhav Agrawal, Martin Heni, Patrick Schwab, Julia Dienes, Steffen Reichert, Andreas L. Birkenfeld, Hans-Ulrich Haering, Fritz Schick, Norbert Stefan, Andreas Fritsche, Hubert Preissl, Bernhard Schoelkopf, Stefan Bauer, Robert Wagner
Summary: The study indicated that diabetes can be detected through whole-body MRI without additional data, with visceral fat playing a crucial role in diabetes classification. The model identified a high-risk group with increased risk for future diabetes and microalbuminuria.
Article
Neurosciences
Adrian Diaz-Rua, Mauro Chivite, Cristina Velasco, Sara Comesana, Jose L. Soengas, Marta Conde-Sieira
Summary: This study evaluated the main components of the cannabinoid system related to feeding conditions in fish. The results suggest a potential role of the endocannabinoid system in the regulation of food intake in fish, but further research is needed.
NUTRITIONAL NEUROSCIENCE
(2022)
Article
Fisheries
Luis F. Baiao, Filipa Rocha, Tiago Sa, Ana Oliveira, Manuela Pintado, Rui Costa Lima, Luis M. Cunha, Luisa M. P. Valente
Summary: This study investigated the effects of different sources and target incorporation levels of beta-carotene on the color and quality of sea urchin gonads. The results showed that low levels of beta-carotene intake can change the color of gonads, but do not affect the content of carotenoid pigments. Gender and dietary source have significant effects on gonad color and consumer acceptance.
Article
Physiology
Mariana Ferreira, Pedro C. Ribeiro, Laura Ribeiro, Marisa Barata, Valentina F. Domingues, Sara Sousa, Cristina Soares, Alexandra Marques, Pedro Pousao-Ferreira, Jorge Dias, L. Filipe C. Castro, Antonio Marques, Maria L. Nunes, Luisa M. P. Valente
Summary: This study evaluated the impact of biofortified diets containing microalgae, macroalgae, and selenised yeast on gilthead seabream. The results showed that microalgae can partially replace fish meal and fish oil in the diets for seabream. The addition of macroalgae and selenised yeast should be controlled at proper levels. The muscle of seabream fed with microalgae diets had higher EPA and DHA content, and their retention and gain of selenium were also increased. However, more research is needed for iodine fortification in fish.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Fisheries
A. I. G. Raposo, F. Soares, L. E. C. Conceicao, L. M. P. Valente, T. S. Silva
Summary: Mathematical models can be used to estimate the body composition of fish without sacrificing animals. In this study, Nile tilapia body composition data were collected from 138 scientific publications, and predictive models were developed using different combinations of models and calibration methods. The results showed that model predictions are influenced by the type of model, calibration method, and amount of calibration data available. The best predictive models for Nile tilapia body composition were the allometric model and a robust hybrid model, both calibrated assuming multiplicative error.
Article
Fisheries
Jessica Calo, Marta Conde-Sieira, Sara Comesana, Jose L. Soengas, Ayelen M. Blanco
Summary: This study demonstrates the presence of a gut-brain axis in fish, as different types and lengths of fatty acids impact feed intake and appetite-regulatory centers in rainbow trout. The findings have important implications for aquaculture due to variations in fatty acid composition in aquafeeds.
Article
Environmental Sciences
Helena Oliveira, Ana Luisa Maulvault, Sara Castanho, Tiago Repolho, Luisa M. P. Valente, Pedro Pousao-Ferreira, Rui Rosa, Antonio Marques, Patricia Anacleto
Summary: Rising levels of atmospheric CO2 are causing ocean warming and acidification, which have potential negative effects on commercially important fish species. This study examined the effects of ocean acidification (OA) and warming (OW), both individually and combined, on the composition, fitness, and energy budget of juvenile Senegalese sole. The results showed that acidification and warming did not significantly impact the proximate composition and gross energy of the fish. However, OA, OW, and OAW treatments resulted in higher growth rates, metabolic rates, and energy intake compared to control conditions. The study highlights the physiological responses of juvenile Senegalese sole to ocean warming and acidification, emphasizing the importance of understanding the impact of climate change on fisheries.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Fisheries
Jessica Calo, Jose L. Soengas, Jose J. Pastor, Ayelen M. Blanco, Sofia Morais
Summary: This study aimed to investigate the amino acid sensing capacity and hormone production in the gastrointestinal tract (GIT) of rainbow trout in response to proline, fishmeal amino acids, and fishmeal aqueous extract. The results showed that the presence of proline in the GIT led to changes in amino acid sensing systems and hormone production, especially in the proximal regions, accompanied by anorectic response in the hypothalamus. Both the fishmeal aqueous extract and the fishmeal amino acids induced anorectic responses in the hypothalamus, accompanied by increased production of anorectic hormones in the intestine.
Article
Fisheries
F. Lai, S. Comesana, A. S. Gomes, D. Flatejord, I. Tolas, M. Espe, C. De Santis, M. B. Hartviksen, T. Verri, J. L. Soengas, I. Ronnestad
Summary: This study found that high leucine diets reduce feed intake, growth, and hepatosomatic index in Atlantic salmon. It was also found that high leucine diets activate amino acid sensing mechanisms in the brain, which further affects the expression of genes related to appetite control.
Article
Fisheries
Mariana Ferreira, Marina Machado, Catia S. C. Motac, Helena Abreu, Joana Silva, Margarida R. G. Maia, Viswanath Kiron, Benjamin Costas, Luisa M. P. Valente
Summary: Aquaculture intensification is often linked to disease outbreaks, but nutritional approaches, such as algae-derived compounds, can help alleviate the burden caused by diseases. This study evaluated the immunomodulatory activity of an algae blend on farmed seabass's resistance to a bacterial pathogen. The results showed that a 4% inclusion level of the algae blend was the most effective in preventing adhesion and colonization of the pathogen on mucosal tissues, leading to reduced disease progression and mortality.
Article
Fisheries
Ana Basto, Alexandra Marques, Andreia Silva, Tiago Sa, Vera Sousa, M. Beatriz P. P. Oliveira, Tiago Aires, Luisa M. P. Valente
Summary: This study assessed the effects of replacing fishmeal protein with defatted Tenebrio molitor in European sea bass diets. The results showed that replacing 50% of fishmeal protein with defatted Tenebrio molitor significantly improved feed efficiency without affecting fish growth performance. The nutritional and sensory quality traits of the fish fillets were similar between the control and defatted Tenebrio molitor groups.
Article
Chemistry, Applied
Carolina Camacho, Tatiana Correia, Barbara Teixeira, Rogerio Mendes, Luisa M. P. Valente, M. Fernanda Pessoa, M. Leonor Nunes, Amparo Goncalves
Summary: This study aims to report the chemical changes in sea urchin during refrigerated storage and their contribution to taste. The results showed that adenylate energy charge is a suitable indicator of freshness, while amino acids are related to taste and maturation stage. Storage had minimal effect on amino acids, but nucleotides showed potential changes after day 5.
Article
Biochemistry & Molecular Biology
Jessica Calo, Sara Comesana, Angel L. Alonso-Gomez, Jose L. Soengas, Ayelen M. Blanco
Summary: This study provides the first evidence of fatty acid sensing mechanisms in the gastrointestinal tract (GIT) of fish and identifies differences in these mechanisms between rainbow trout and mammals.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Nuria Saiz, Cristina Velasco, Nuria de Pedro, Jose Luis Soengas, Esther Isorna
Summary: This study aimed to investigate the potential role of insulin as an intake signal mediating liver entrainment in fish. The experiments showed that the presence of insulin directly increased the abundance of per1a and per2 transcripts in the fish liver. It was found that the involvement of the PI3K/AKT pathway is crucial for insulin-mediated liver entrainment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Agriculture, Dairy & Animal Science
Ana Basto, Luisa M. P. Valente, Vera Sousa, Marta Conde-Sieira, Jose L. Soengas
Summary: This study evaluated the impact of partial and total fishmeal replacement by insect meal on intermediary metabolism of European sea bass. The results showed that the selected insect meal can replace 50% of fishmeal without adversely affecting liver health or intermediary metabolism. However, total fishmeal replacement may compromise fish health in the long-term.
JOURNAL OF ANIMAL SCIENCE
(2023)
Proceedings Paper
Agricultural Engineering
M. Nunes da Silva, A. P. G. Fernandes, M. V. Vasconcelos, L. M. P. Valente, S. M. P. Carvalho
Summary: The study found that kiwifruit plants grown under different nitrogen sources exhibited variations in response to Psa infection, with plants supplied with nitrate showing better disease resistance and higher mineral contents.
X INTERNATIONAL SYMPOSIUM ON KIWIFRUIT
(2022)
Article
Fisheries
Hunter S. Bailey, Ashley N. Fincannon, Lee A. Fuiman
Summary: This study investigated the transfer of fatty acids from broodstock diets to eggs and the time needed for the eggs to equilibrate to the diet in Southern flounder. The findings indicate that different diet treatments significantly affect the fatty acid composition of eggs, and it takes 8-16 weeks for the eggs to adapt to changes in the adult diet. These results are important for improving broodstock diets and feeding protocols in stock-enhancement programs.
Article
Fisheries
Yu Liu, Mingtao Lei, Hector Victor, Yan Wang
Summary: This study confirms the feasibility of replacing raw fish diet with a formulated diet in commercial farming of large yellow croaker, which can increase fish survival and yield, and reduce feed cost and body lipid deposition.
Article
Fisheries
Xiaoyan Zhang, Lize San, Yucong Yang, Yuehong Tao, Jiangong Ren, Yufeng Liu, Zhongwei He, Jiashuo Di, Ziteng Pei, Guixing Wang, Jilun Hou
Summary: Gynogenesis is an effective technique for establishing homogeneous lines and confirming potential chromosomal mechanisms of sex determination in fish. This study successfully induced gynogenetic families in Thamnaconus modestus and established a complete method for gynogenesis induction.
Article
Fisheries
Julieta C. Martinelli, Megan Considine, Helen R. Casendino, Carolyn M. Tarpey, Isadora Jimenez-Hidalgo, Jacqueline L. Padilla-Gamino, Teri L. King, Lorenz Hauser, Steven Rumrill, Chelsea L. Wood
Summary: Shell-boring polychaetes have caused significant damage to mariculture operations worldwide, particularly in the US Pacific region. This study provides a comprehensive dataset on the prevalence, species distribution, and environmental associations of these parasites, highlighting the impact of season, culturing methods, and environmental factors on infestation.
Article
Fisheries
Juan Gao, Xueshan Li, Kangle Lu, Kai Song, Jian Zhang, Ling Wang, Chunxiao Zhang
Summary: This study investigated the effects of dietary protein levels on growth performance, antioxidant capacity, digestive enzyme activity, and metamorphosis rate of bullfrog tadpoles. The optimal dietary protein level for bullfrog tadpoles was estimated to be 42.49%-46.50% of the diet.
Article
Fisheries
Qiang Li, Lijun Duan, Dongsheng Jin, Yuxin Chen, Yirong Lou, Qianjin Zhou, Zhongjie Xu, Fangjie Chen, Hongxian Chen, Guizong Xu, Maocang Yan, Guanjun Yang, Jianfei Lu, Yanjun Zhang, Jiong Chen
Summary: This study developed a centrifugal microfluidic chip with on-chip RPA to detect five pathogenic microorganisms. The chip enabled the parallel analysis of six genetic markers from a single sample and allowed for the highly automated detection of multiple samples. Compared with PCR and DNA sequencing, the on-chip RPA assay showed high sensitivity and specificity for detecting multiple pathogens in shrimp aquaculture.
Article
Fisheries
Xingchen Huo, Pengxu Wang, Fengxia Zhao, Qian Liu, Qingqing Tian, Lingjie Tang, Maolin Lv, Zhaohui Wei, Chunrong Yang, Jianguo Su
Summary: Bacterial diseases in aquaculture ponds have negative effects on sustainable development. The use of composite I20 biotherapy has been shown to effectively treat bacterial diseases in bullfrog ponds, providing a new strategy for controlling bacterial diseases in aquaculture.
Article
Fisheries
Peng Yin, Takaya Saito, Per Gunnar Fjelldal, Bjorn Tharandur Bjornsson, Sofie Charlotte Remo, Sandeep Sharma, Rolf Erik Olsen, Kristin Hamre
Summary: This study aims to investigate the effect of seasonal changes in temperature and photoperiod on the redox metabolism of Atlantic salmon at the molecular level. The research findings suggest that the changing photoperiod and temperature influenced the redox metabolism of Atlantic salmon, highlighting the importance of oxidative status in the ecological implications.
Article
Fisheries
Nicholas Oppong Mensah, Jeffery Kofi Asare, Emmanuel Tetteh-Doku Mensah, Ernest Christlieb Amrago, Frank Osei Tutu, Anthony Donkor
Summary: This study investigates aquaculture farmers' preference for climate-smart aquaculture insurance products, the challenges they face, and their preferred insurance coverage. The results show that farmers prefer Climate-Induced Aquaculture Stock Mortality Insurance and the most significant constraint is the delay in claim settlement.
Article
Fisheries
Qiu-Ping Chai, Pei Wu, Wei-Dan Jiang, Yang Liu, Hong-Mei Ren, Xiao-Wan Jin, Lin Feng, Xiao-Qiu Zhou
Summary: The study found that appropriate levels of potassium diformate (KDF) can enhance the immune defense and mediate the inflammatory process in fish, possibly through the regulation of T cell differentiation via JAK-STAT and NF-kappa B signaling pathways.
Article
Fisheries
Tian Zhu, Haomin Jia, Haopeng Zhang, Yujing Xiao, Cui Han, Jiaxin Yang
Summary: Chicken manure has significant effects on the cultivation of Chlorella and rotifers. The optimal amount of chicken manure extract for continuous cultivation is 10 mLL-1. Chicken manure can promote the growth of Chlorella and improve the fatty acid composition, indirectly enhancing the growth condition and fatty acid content of rotifers.
Article
Fisheries
Zheng Luo, Yang Yu, Zhenning Bao, Fuhua Li
Summary: This study analyzed the heritability and genetic correlation of two growth traits in Pacific white shrimp and evaluated the genomic prediction using different genomic selection models. The results showed that the NeuralNet model had the highest prediction accuracy and better prospects for predicting shrimp growth traits.
Article
Fisheries
Alberto Ruiz, Ignasi Sanahuja, Karl B. Andree, Dolors Furones, Paul G. Holhorea, Josep A. Calduch-Giner, Jose J. Pastor, Marc Vinas, Jaume Perez-Sanchez, Sofia Morais, Enric Gisbert
Summary: Supplementing diets with a combination of spice oleoresins can reduce lipid accumulation and inflammation in farmed fish. The combination of spice oleoresins also has an immunomodulatory effect on the fish's intestinal immune system, potentially offering anti-inflammatory benefits.
Article
Fisheries
Beibei Zhao, Renhui Mei, Le Li, Di Hu, Lei Li
Summary: This study reveals that JfCXCL8_L1a and JfCXCL8_L1b have different immune pathways, and JfCXCL8_L1b plays a significant role in enhancing the adaptive immunity of T cell-dependent antigen.
Article
Fisheries
Yuhang Liu, Danying Cao, Nan Wu, Xuyang Zhao, Qingsong Zhu, Lian Su, Fatima Altaf, Qianqian Zhang, Haokun Liu, Yongming Li, Bruno Hamish Unger, Yingyin Cheng, Wanting Zhang, Aihua Li, Yaping Wang, Xiao-Qin Xia
Summary: Based on previous research, sinomenine has been found to protect mucosal immunity in farmed fish species by preventing intestinal pathological changes and regulating gene expression related to inflammation. It also enhances immune homeostasis and controls the growth of pathogenic bacteria.