Journal
MICROVASCULAR RESEARCH
Volume 96, Issue -, Pages 55-63Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.mvr.2014.06.006
Keywords
Imaging; Lymphatic vessels; Technologies; Lymph node; Lymphatic function; Lymphatic metastasis; Lymphography; Fluorescence; Models; Clinical
Categories
Funding
- National Institutes of Health [R01CA149285, R00-CA137167, R21-AI097745, DP2-OD008780]
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Visualization of the lymphatic system is clinically necessary during diagnosis or treatment of many conditions and diseases; it is used for identifying and monitoring lymphedema, for detecting metastatic lesions during cancer staging and for locating lymphatic structures so they can be spared during surgical procedures. Imaging lymphatic anatomy and function also plays an important role in experimental studies of lymphatic development and function, where spatial resolution and accessibility are better. Here, we review technologies for visualizing and imaging the lymphatic system for clinical applications. We then describe the use of lymphatic imaging in experimental systems as well as some of the emerging technologies for improving these methodologies. (C) 2014 Elsevier Inc. All rights reserved.
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