Article
Medicine, General & Internal
Daniel B. C. Dos Santos, Luis Henrique W. Gowdak, Elias David-Neto, Felizardo A. Nataniel, Jose J. G. De Lima, Luiz A. Bortolotto
Summary: There is a need for a simple, inexpensive, and reliable noninvasive testing method to predict coronary artery disease in patients with chronic kidney disease. Peripheral artery disease (PAD) can be diagnosed using both palpation and ultrasound (USD). Palpation-diagnosed PAD is a better predictor of combined cardiovascular events and death, as well as being associated with CAD severity and likelihood of intervention.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Sebastian Beer, Jonas Babel, Neef Martin, Valentin Blank, Johannes Wiegand, Thomas Karlas
Summary: Fatty liver diseases, especially metabolic dysfunction-associated fatty liver disease, are becoming increasingly important for patients and healthcare providers. The underlying pathophysiological links between fatty liver disease and coronary artery disease are not fully understood.
Review
Biochemistry & Molecular Biology
Pietro Scicchitano, Micaela De Palo, Giuseppe Parisi, Margherita Ilaria Gioia, Marco Matteo Ciccone
Summary: The impact of coronary artery disease (CAD) on mortality and disabilities is well-established. Revascularization procedures have reduced adverse cardiovascular events in atherosclerosis patients, with coronary artery bypass graft (CABG) being recommended for specific alterations in the coronary tree. Doppler ultrasonography (DU) may serve as a reliable technique for assessing the patency of left internal mammary artery (LIMA) graft in CABG patients. This review aims to evaluate the impact of DU on LIMA graft patency evaluation in post-CABG follow-up.
Article
Cardiac & Cardiovascular Systems
Quanjun Liu, Han Yin, Cheng Jiang, Mingyu Xu, Yuting Liu, Anbang Liu, Haochen Wang, Bingqing Bai, Fengyao Liu, Lan Guo, Huan Ma, Qingshan Geng
Summary: This study found that depression has different predictive values for clinical outcomes among patients with different levels of cardiac systolic function. Depression is more closely related to clinical outcomes in CAD patients with preserved LVEF than in those with decreased LVEF. Including psychological factors in risk prediction models may be beneficial.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Medicine, General & Internal
Matthias Renker, U. Joseph Schoepf, Won Keun Kim
Summary: Computed tomography angiography (CTA) is essential for preprocedural planning of transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis (AS). CTA provides diagnostic information on aortic valve calcification, allows for customized valve selection, and helps exclude coronary artery disease (CAD). However, the utilization of CTA for coronary artery evaluation remains limited due to the high risk of CAD coexistence. In this article, the authors discuss the technical requirements, potential pitfalls, and current literature on combined CTA coronary artery assessment and preprocedural TAVI evaluation.
Article
Cardiac & Cardiovascular Systems
Jennifer Holland, Leanne Eveson, David Holdsworth, Edward Nicol
Summary: This study compared the diagnostic outcomes and occupational recommendations of two different investigative pathways for coronary artery disease (CAD) in high-hazard employees. The results showed that the CACS pathway led to more individuals returning to employment, but with a potential risk of occupational CAD.
JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY
(2022)
Article
Immunology
Samuel R. Schnittman, Michael T. Lu, Thomas Mayrhofer, Tricia H. Burdo, Kathleen Fitch, Sara McCallum, Evelynne S. Fulda, Markella Zanni, Borek Foldyna, Carlos Malvestutto, Carl J. Fichtenbaum, Judith A. Aberg, Gerald S. Bloomfield, Edgar T. Overton, Judith Currier, Pablo Tebas, Beverly E. Sha, Heather J. Ribaudo, Jacqueline M. Flynn, Pamela S. Douglas, Kristine M. Erlandson, Steven K. Grinspoon
Summary: This study found no association between CMV IgG titer and coronary artery plaque phenotypes in HIV patients. However, CMV IgG titer was associated with certain inflammatory biomarkers. These results suggest that CMV infection may not be the primary mechanism contributing to increased cardiovascular disease risk.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jade Geerlings-Batt, Zhonghua Sun
Summary: This study aimed to explore the relationship between coronary artery disease (CAD) and the angle between the right coronary artery (RCA) and the aorta. By measuring the coronary angles in normal and CAD cases, it was found that the RCA-aorta angle was significantly smaller in the CAD group, suggesting a relationship between narrow RCA-aorta angle and CAD.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Pediatrics
Justin Pick, Mounica Y. Rao, Kathryn Dern, Shuo Wang, Jacqueline Szmuszkovicz, Sharon Wagner-Lees, Sarah Badran, Pierre C. Wong, Jodie K. Votava-Smith
Summary: During the first 6 months of the 2020 coronavirus pandemic, there was a high incidence of coronary aneurysms in patients with multisystem inflammatory syndrome in children, as well as an increased incidence of cardiac dysfunction compared to previous years in patients with Kawasaki disease.
JOURNAL OF PEDIATRICS
(2022)
Article
Cardiac & Cardiovascular Systems
Michel Zeitouni, Guillaume Marquis-Gravel, Nathaniel R. Smilowitz, Pearl Zakroysky, Daniel M. Wojdyla, Amin P. Amit, Sunil V. Rao, Tracy Y. Wang
Summary: The use of prophylactic mechanical circulatory support (MCS) has increased over time in elective percutaneous coronary intervention (PCI) for patients with stable coronary artery disease. Intra-aortic balloon pump use is associated with a higher risk of major adverse cardiac events but lower risk of procedural complications compared with other MCS.
CIRCULATION-CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Immunology
Marton Kolossvary, Chris deFilippi, Michael T. Lu, Markella V. Zanni, Evelynne S. Fulda, Borek Foldyna, Heather Ribaudo, Thomas Mayrhofer, Ann C. Collier, Gerald S. Bloomfield, Carl Fichtenbaum, Edgar T. Overton, Judith A. Aberg, Judith Currier, Kathleen V. Fitch, Pamela S. Douglas, Steven K. Grinspoon
Summary: Despite low traditional cardiovascular disease risk, subclinical coronary artery disease is common among people with HIV. Unique patterns of novel proteins in inflammatory and immune pathways are associated with different plaque phenotypes. Further investigation of these targets may help reduce atherosclerosis and cardiovascular disease in this population.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Multidisciplinary Sciences
Daniel T. Y. Ang, Novalia P. Sidik, Andrew J. Morrow, Robert Sykes, Margaret B. McEntegart, Colin Berry
Summary: Approximately 40% of patients with angina have no obstructive coronary artery disease. Coronary function tests can diagnose and treat different subgroups. The tests measure coronary function and vascular dilation. This practical guide provides information on the preparation and administration of the diagnostic procedure.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
(2022)
Article
Immunology
Emma F. Avery, Julia N. Kleynhans, Bruno Ledergerber, Isabella C. Schoepf, Christian W. Thorball, Neeltje A. Kootstra, Peter Reiss, Lene Ryom, Dominique L. Braun, Maria C. Thurnheer, Catia Marzolini, Marco Seneghini, Enos Bernasconi, Matthias Cavassini, Helene Buvelot, Roger D. Kouyos, Jacques Fellay, Huldrych F. Guenthard, Philip E. Tarr
Summary: In Switzerland, leukocyte count is independently associated with coronary artery disease (CAD) events in people with HIV (PWH), even after adjusting for traditional and HIV-related risk factors.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Cardiac & Cardiovascular Systems
D. Elizabeth Le, Manuel Garcia-Jaramillo, Gerd Bobe, Armando Alcazar Magana, Ashish Vaswani, Jessica Minnier, Donald B. Jump, Diana Rinkevich, Nabil J. Alkayed, Claudia S. Maier, Sanjiv Kaul
Summary: Oxylipin levels in plasma can help diagnose and predict prognosis of coronary artery disease, with specific panels of oxylipins showing high sensitivity and specificity in distinguishing disease severity and predicting survival outcomes.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Maurizio Lodi Rizzini, Sakura Nagumo, Diego Gallo, Jeroen Sonck, Takuya Mizukami, Fabrizio D'Ascenzo, Dimitri Buytaert, Umberto Morbiducci, Bernard De Bruyne, Claudio Chiastra, Carlos Collet
Summary: The assessment of lesion length in coronary artery disease shows differences between morphological and functional evaluations. The mismatch in lesion length between angiography, OCT, and mFFR can affect the outcomes of PCI and may influence clinical decision-making regarding revascularization strategy.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Obstetrics & Gynecology
Sandra Lynn Jaya-Bodestyne, Lai Heng Lee, Lay Kok Tan, Kok Hian Tan, Truls Ostbye, Rahul Malhotra, John Allen, Sophie Seine Xuan Tan, Melinda Si Yun Tan, Lawrence Cheng Kiat Ng, Yang Yong, Thiam Chye Tan
Summary: This case-control study identified smoking and preterm delivery as the most significant risk factors for pregnancy-associated VTE. Other high-risk factors included Malay race, multiparity, non-0 blood group, and caesarean section. These findings can be useful in developing thromboprophylaxis strategies for pregnancy and the postpartum period, especially in Singapore.
JOURNAL OF PERINATAL MEDICINE
(2021)
Article
Peripheral Vascular Disease
Luke Boylan, Craig Nesbitt, Lesley Wilson, John Allen, Andrew Sims, Ina Guri, Philip Mawson, Crispian Oates, Gerard Stansby
Summary: The study assessed the accuracy of the ECQ for PAD diagnosis using DUS and found that the ECQ had relatively poor overall diagnostic test accuracy in isolation, but could be helpful in ruling out or as supplementary test in General Practice for symptomatic disease diagnosis.
Article
Biophysics
John Allen, Haipeng Liu, Sadaf Iqbal, Dingchang Zheng, Gerard Stansby
Summary: The proof-of-concept study demonstrated the potential of a deep learning-based classification method for detecting peripheral arterial disease using toe PPG signals. The method showed high sensitivity and specificity in detecting PAD, making it a promising tool for use in clinical settings.
PHYSIOLOGICAL MEASUREMENT
(2021)
Article
Biophysics
Haipeng Liu, John Allen, Syed Ghufran Khalid, Fei Chen, Dingchang Zheng
Summary: Filtering can significantly influence the timing of feature points on PPG signals, with measurement site and type of pulse feature playing important roles. Finger measurement site showed higher overall time shift and lower intra-subject variability compared to other sites, highlighting the need to consider these factors in PPG signal processing.
PHYSIOLOGICAL MEASUREMENT
(2021)
Review
Cardiac & Cardiovascular Systems
Peter H. Charlton, Birute Paliakait, Kristjan Pilt, Martin Bachler, Serena Zanelli, Daniel Kulin, John Allen, Magid Hallab, Elisabetta Bianchini, Christopher C. Mayer, Dimitrios Terentes-Printzios, Verena Dittrich, Bernhard Hametner, Dave Veerasingam, Dejan Zikic, Vaidotas Marozas
Summary: This review summarizes the research on assessing vascular age using the photoplethysmogram (PPG) signal. The methods can be divided into those using a single PPG signal, those using multiple PPG signals, and those using PPG in combination with other signals. The review presents evidence on the performance, repeatability and reproducibility, and clinical utility of PPG-derived parameters for assessing vascular age.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2022)
Article
Surgery
Samuel Huthart, Crispian Oates, John Allen, Kathia Fiaschi, Andrew J. Sims, Gerard Stansby
Summary: The study validates the diagnostic performance of the standardised DUS scoring system for the identification of peripheral arterial disease (PAD), as well as its capacity to grade disease severity. The system shows moderate agreement with ankle brachial pressure index (ABPI) in determining disease severity.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2022)
Article
Surgery
Zhiyan Yan, Adele Wong, Ruey Pyng Ng, Yien Sien Lee, Mei En Annabelle Lim, Lester Chee Hao Leong, John Allen, Geok Hoon Lim
Summary: This study aimed to determine the rate of nodal pathological complete response in breast cancer patients with high nodal burden who received neoadjuvant chemotherapy. The results showed that NACT could achieve nodal pCR in these patients to some extent, especially in certain subtypes.
Article
Peripheral Vascular Disease
Gerard Stansby, Andrew J. Sims, Lesley Wilson, Tom A. W. Beale, James Wightman, Ina Guri, Scott Wilkes, Shona Haining, John Allen
Summary: This study assessed the diagnostic accuracy of multi-site photoplethysmography (MPPG), an alternative non-invasive test for peripheral arterial disease (PAD), in primary care. The results showed that MPPG has comparable sensitivity to ankle brachial pressure index (ABPI), but is quicker, automated, and simpler to perform than ABPI, offering the potential for rapid and accessible PAD assessments in primary care.
Article
Engineering, Biomedical
Sadaf Iqbal, Sharad Agarwal, Ian Purcell, Alan Murray, Jaume Bacardit, John Allen
Summary: This study used a novel approach, DL-PPG, which uses deep learning analysis of bilateral-site photoplethysmography waveforms, to identify patients with coronary artery disease (CAD). The results showed that DL-PPG had higher sensitivity and specificity compared to conventional machine learning methods in classifying CAD. This approach could provide significant value in low-cost, portable, and easy-to-use diagnostics for CAD in various clinical settings.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2023)
Article
Biophysics
Peter H. Charlton, John Allen, Raquel Bailon, Stephanie Baker, Joachim A. Behar, Fei Chen, Gari D. Clifford, David A. Clifton, Harry J. Davies, Cheng Ding, Xiaorong Ding, Jessilyn Dunn, Mohamed Elgendi, Munia Ferdoushi, Daniel Franklin, Eduardo Gil, Md Farhad Hassan, Jussi Hernesniemi, Xiao Hu, Nan Ji, Yasser Khan, Spyridon Kontaxis, Ilkka Korhonen, Panicos A. Kyriacou, Pablo Laguna, Jesus Lazaro, Chungkeun Lee, Jeremy Levy, Yumin Li, Chengyu Liu, Jing Liu, Lei Lu, Danilo P. Mandic, Vaidotas Marozas, Elisa Mejia-Mejia, Ramakrishna Mukkamala, Meir Nitzan, Tania Pereira, Carmen C. Y. Poon, Jessica C. Ramella-Roman, Harri Saarinen, Md Mobashir Hasan Shandhi, Hangsik Shin, Gerard Stansby, Toshiyo Tamura, Antti Vehkaoja, Will Ke Wang, Yuan-Ting Zhang, Ni Zhao, Dingchang Zheng, Tingting Zhu
Summary: This article introduces the application of wearable photoplethysmography technology in health monitoring, discusses key topics in related areas, and provides guidance for researchers developing wearable photoplethysmography technology.
PHYSIOLOGICAL MEASUREMENT
(2023)
Article
Physiology
Sadaf Iqbal, Jaume Bacardit, Bridget Griffiths, John Allen
Summary: This study demonstrates the potential of using convolutional neural networks for DL-PPG classification to detect SSc. EfficientNetB0 outperforms GoogLeNet, and both CNNs perform better than traditional machine learning methods. This automated AI approach has significant benefits for SSc diagnostics in various clinical settings.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Stephan Mieke, Alan Murray
Summary: This study explored the potential of a simulator for oscillometric blood pressure measurement devices, and found that the simulator could reproduce oscillometric pulses with high repeatability and accuracy. This suggests that the simulator has the potential to become a secondary standard for oscillometric sphygmomanometers.
BIOMEDICAL PHYSICS & ENGINEERING EXPRESS
(2023)
Article
Health Care Sciences & Services
Kim Bul, Nikki Holliday, Mohammad Rashed Alam Bhuiyan, Cain C. T. Clark, John Allen, Petra A. Wark
Summary: This study examined the usability and preliminary efficacy of a web-based AI-driven nutrition platform for people with diabetes and their carers. The results showed reductions in weight and waist size after using the platform. Most participants found the platform to be accessible and user-friendly, but suggested adding an education component for those less familiar with the role of diet in diabetes management.
JMIR HUMAN FACTORS
(2023)
Article
Physiology
James Frith, Lisa Robinson, Jake Ryan Gibbon, John Allen
Summary: The study concludes that increasing lower limb muscle strength does not improve the effectiveness of the skeletal muscle pump and is not an efficacious intervention for orthostatic hypotension in older people. Additionally, the use of below knee compression is unlikely to be clinically effective in this population.
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING
(2023)
Article
Medicine, Research & Experimental
Fatemeh Y. Sinaki, Rabab Ward, Derek Abbott, John Allen, Richard Ribon Fletcher, Carlo Menon, Mohamed Elgendi
Summary: Sinaki et al. have highlighted ethnic disparities in 12 publicly-available pulse oximetry databases, and discussed the potential consequences of such disparities on pulse oximetry device and algorithm development.
COMMUNICATIONS MEDICINE
(2022)
Article
Peripheral Vascular Disease
Jingting Yao, Justin D. Sprick, Jinhee Jeong, Jeanie Park, David A. Reiter
Summary: This study used time-frequency spectral analysis of resting near-infrared spectroscopy (NIRS) signals to evaluate the regulation of peripheral microvascular perfusion in CKD patients. The findings suggest that CKD patients have impaired neurogenic and endothelial functions, which may be associated with increased sympathetic activity and reduced endothelial function in CKD.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Yoh Sugawara, Yusuke Mizuno, Shinya Oku, Yuri Sawada, Takahisa Goto
Summary: This study investigated the role of Protein kinase D (PKD) in aortic contraction and hemodynamics, finding that PKD1 plays a crucial role in these processes through phosphorylation of MYPT1 and actin polymerization in a calcium-independent manner.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Xuenan Zhuang, Guiqin He, Yunkao Zeng, Miaoling Li, Yongyue Su, Xuelin Chen, Yining Zhang, Yuhong Gan, Feng Wen, Xiongze Zhang
Summary: This study assessed the impact of acute, heavy alcohol consumption on the ocular microvasculature. The findings suggest that excessive alcohol consumption leads to vasoconstriction in ocular arterioles and vasodilation in capillaries, particularly evident 1-hour post-consumption.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Ayuki Nakano, Akane Morita, Shiho Arima, Tohru Nagamitsu, Tsutomu Nakahara
Summary: This study examines the preventative and therapeutic effects of inhibiting mammalian target of rapamycin complex 1 (mTORC1) on abnormal retinal blood vessels in a rat model of retinopathy of prematurity (ROP). The results suggest that mTORC1 activation in proliferating endothelial cells contributes to the appearance and progression of ROP-like retinal blood vessels. Inhibition of mTORC1 may be a promising approach for selectively targeting abnormal retinal blood vessels in ROP.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Bing Wang, Xiaohong Song, Xu Zhang, Yuan Li, Mengting Xu, Xueting Liu, Bingwei Li, Sunjing Fu, Hao Ling, Yingyu Wang, Xiaoyan Zhang, Ailing Li, Mingming Liu
Summary: This study found that glycine supplementation can improve pancreatic microcirculation in T1DM mice and reverse the production of inflammatory cytokines. Furthermore, glycine supplementation also alleviates damage to pancreatic islet and vascular tissues, suggesting a potential therapeutic effect for T1DM.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Merve Erkisa Genel, Kaan Adacan, Selin Selvi, Deniz Erol Kutucu, Ayca Uvez, Elif Ilkay Armutak, Abdurrahman Sengul, Engin Ulukaya, Ebru Gurel Gurevin
Summary: This study investigated the anti-growth/cytotoxic effect of a dinuclear Pd(II) complex on breast cancer cell lines and confirmed its anti-migration and antiangiogenic properties. The results suggest the potential of this complex in the treatment of breast cancer.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Cedric Mueller, Christoph Hauser, Justin Carrard, Konstantin Gugleta, Timo Hinrichs, Arno Schmidt-Trucksass, Henner Hanssen, Lukas Streese
Summary: This study aimed to evaluate the differences in microvascular health between normotensive individuals and patients with arterial hypertension and to assess the effects of short-term high-intensity interval training (HIIT) on microvascular health in patients with arterial hypertension. The study found that short-term HIIT can ameliorate hypertension-induced retinal microvascular abnormalities in patients with arterial hypertension.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Yuyang Hou, Wenjing Du, Qiong Wu, Xinyu Chai, Yinan Wang, Yingqian Mi, Yuan Tian, Mengyan Tang, Jun Li, Dongmei Yan
Summary: This study identified a prognostic signature consisting of four genes in bladder cancer patients and utilized angiogenesis-related genes and molecular subtypes to construct this signature, which could help predict survival outcomes. The study also evaluated immune cell infiltration and predicted chemotherapeutic responses, confirming the effectiveness of this prognostic signature.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Sean D. Mcgarry, Cynthia Adjekukor, Suchit Ahuja, Jasper Greysson-Wong, Idy Vien, Kristina D. Rinker, Sarah J. Childs
Summary: The article introduces a software tool called Vessel Metrics for analyzing developmental vascular microscopy images, which can expedite the analysis process and ensure consistency between research groups. The tool includes a segmentation algorithm that accurately quantifies different image types and has been validated in zebrafish and mouse models.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Y. P. Latul, C. Ince, N. E. van Trommel, A. van den Brandhof-van den Berg, J. P. W. R. Roovers, A. W. Kastelein
Summary: This study evaluated the real-time detection capability of handheld vital microscopy (HVM) for cervical intraepithelial neoplasia (CIN) and cervical cancer (CC). The results showed that HVM enables easy, real-time, and non-invasive assessment of cervical lesions through the detection of microvascular alterations. This method has the potential to be used for point-of-care screening, reducing unnecessary surgical interventions.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Zhifei Liu, Jieqiong Zhang, Xue Li, Qiumei Hu, Xi Chen, Linlin Luo, Liqianyu Ai, Jian Ye
Summary: The study revealed that astrocytic YAP can alleviate retinal pathological angiogenesis by inhibiting overactivation of astrocytes, thereby suppressing excessive VEGF-A production and neuroinflammation.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Robert G. Hahn
Summary: The fast-exchange interstitial fluid compartment is directly connected to the circulating blood, while the slow-exchange compartment is not.
MICROVASCULAR RESEARCH
(2024)
Review
Peripheral Vascular Disease
Nadia Hamjane, Mohcine Bennani Mechita, Naima Ghailani Nourouti, Amina Barakat
Summary: Gut microbiota dysbiosis plays a crucial role in the development of obesity-related metabolic abnormalities, including insulin resistance, type 2 diabetes, and cardiovascular diseases. Inflammation is a major mechanism linking gut microbiota dysbiosis to obesity-associated metabolic complications.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Guangzhen Zhou, Yan Gao, Yanbin Shi, Shengnan Qiu, Guimei Lin, Xinbing Ding, Wenguang Wang, Yihua Feng, Fei Wang, Jinwei Qiao
Summary: This study utilized an in vitro biomimetic experimental system to investigate the transvascular transport of nano-preparations, and found that the pressure gradient between vascular fluid pressure and interstitial fluid pressure determines the existence of the enhanced penetration and retention effect of nanopreparations.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Kenji Chamoto, Barry C. Gibney, Willi L. Wagner, Maximilian Ackermann, Hassan A. Khalil, Steven J. Mentzer
Summary: In the study, the process of angiogenesis in adult regenerating tissue was investigated by grafting portions of the regenerating lung onto the chick chorioallantoic membrane. The results showed peri-graft angiogenesis, particularly in the cardiac lobe. Functional vascular connections were observed between the cardiac lobe and the chick chorioallantoic membrane vascular network. Elevated gene expression levels were found in the cardiac lobe compared to other lobes.
MICROVASCULAR RESEARCH
(2024)
