Article
Multidisciplinary Sciences
Xiaoguang Tian, Yuyan Chen, Piotr Majka, Diego Szczupak, Yonatan Sanz Perl, Cecil Chern-Chyi Yen, Chuanjun Tong, Furui Feng, Haiteng Jiang, Daniel Glen, Gustavo Deco, Marcello G. P. Rosa, Afonso C. Silva, Zhifeng Liang, Cirong Liu
Summary: This article introduces an integrated resource of awake resting-state fMRI and neuronal tracing data of marmosets to better understand the structural-functional relationships of brain connections.
NATURE COMMUNICATIONS
(2022)
Article
Neurosciences
Shahrzad Moinian, Viktor Vegh, David Reutens
Summary: This study developed an automated method for cortical parcellation using MR fingerprinting residual analysis and machine learning classification. The findings provide the foundation for employing unsupervised learning algorithms for whole-cortex structural parcellation in individuals.
Article
Multidisciplinary Sciences
Roey Schurr, Aviv A. Mezer
Summary: The study developed a method based on Nissl staining technique to quantify the structure and orientation of axons, applicable to various datasets. Utilizing structure tensor analysis, fine details of axonal architecture can be extracted effectively.
Article
Multidisciplinary Sciences
Holly D. H. Brown, Richard P. Gale, Andre D. Gouws, Richard J. W. Vernon, Archana Airody, Rachel L. W. Hanson, Heidi A. Baseler, Antony B. Morland
Summary: Macular degeneration (MD) leads to a progressive loss of central vision and is associated with structural changes in the grey and white matter in the posterior visual pathway. This study aimed to understand the progression of these changes over time.
SCIENTIFIC REPORTS
(2023)
Article
Clinical Neurology
David J. Lin, Kimberly S. Erler, Samuel B. Snider, Anna K. Bonkhoff, Julie A. DiCarlo, Nicole Lam, Jessica Ranford, Kristin Parlman, Audrey Cohen, Jennifer Freeburn, Seth P. Finklestein, Lee H. Schwamm, Leigh R. Hochberg, Steven C. Cramer
Summary: The study found that cognitive demands influenced upper extremity motor performance during recovery from acute stroke, with patients performing significantly worse on tasks with higher cognitive demands. Motor performance was related to cognitive dysfunction, especially in tasks involving cognitive demands, and neuroanatomic injury was associated with both the type of task and the location of the injury.
Article
Anatomy & Morphology
Richard Jarrett Rushmore, Sylvain Bouix, Marek Kubicki, Yogesh Rathi, Edward Yeterian, Nikos Makris
Summary: Comparative structural neuroanatomy is essential for understanding human brain structure and function. This study developed a comparative parcellation reasoning system based on cytoarchitectonic mapping, providing a theoretical foundation for mapping neural systems in different species. The methodology presented here can be used for morphometric analysis, generation of atlases, and localization of structural lesions.
FRONTIERS IN NEUROANATOMY
(2022)
Article
Neurosciences
Sebastien Naze, Timothee Proix, Selen Atasoy, James R. Kozloski
Summary: Recent studies have shown that local gray matter connections play a crucial role in the formation of connectome harmonic patterns, which is consistent across different cortical surface templates and resolutions. Alterations of local and long-range connectivity matrices can affect the spatial patterns of connectome harmonics.
Article
Multidisciplinary Sciences
Sofie L. Valk, Ting Xu, Casey Paquola, Bo-yong Park, Richard A. Bethlehem, Reinder Vos de Wael, Jessica Royer, Shahrzad Kharabian Masouleh, Seyma Bayrak, Peter Kochunov, B. T. Thomas Yeo, Daniel Margulies, Jonathan Smallwood, Simon B. Eickhoff, Boris C. Bernhardt
Summary: This study investigates the macroscopic organization of cortical structure-function coupling and uncoupling in different transmodal systems, and finds that genetic and evolutionary uncoupling between structure and function may support the emergence of complex forms of cognition.
NATURE COMMUNICATIONS
(2022)
Article
Mathematical & Computational Biology
Sander Lamballais, Ryan L. Muetzel
Summary: The QDECR package is a flexible and extensible R package designed for group-level statistical analysis of cortical morphology, specifically tailored for large population-based epidemiological studies. It supports vertex-wise linear regression and can handle both unimputed and imputed datasets with extensive modeling options. QDECR's modular design allows for implementation of new statistical models and features commonly used in population-based and clinical studies.
FRONTIERS IN NEUROINFORMATICS
(2021)
Article
Multidisciplinary Sciences
Shuaibin Chang, Divya Varadarajan, Jiarui Yang, Ichun Anderson Chen, Sreekanth Kura, Caroline Magnain, Jean C. Augustinack, Bruce Fischl, Douglas N. Greve, David A. Boas, Hui Wang
Summary: This study established a generalized linear model based on Mie scattering theory that quantitatively links tissue scattering to myelin content and neuron density in the human brain. A strong linear relationship between scattering coefficient and myelin content was reported across different regions of the brain, with neuronal cell body being a secondary contribution to overall scattering. The optical property of OCT provides a label-free solution for quantifying volumetric myelin content and neuron cells in the human brain.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Nerisa Banaj, Daniela Vecchio, Fabrizio Piras, Pietro De Rossi, Juan Bustillo, Simone Ciufolini, Paola Dazzan, Marta Di Forti, Erin W. Dickie, Judith M. Ford, Paola Fuentes-Claramonte, Oliver Gruber, Amalia Guerrero-Pedraza, Holly K. Hamilton, Fleur M. Howells, Bernd Kraemer, Stephen M. Lawrie, Daniel H. Mathalon, Robin Murray, Edith Pomarol-Clotet, Steven G. Potkin, Adrian Preda, Joaquim Radua, Anja Richter, Raymond Salvador, Akira Sawa, Freda Scheffler, Kang Sim, Filip Spaniel, Dan J. Stein, Henk S. Temmingh, Sophia I. Thomopoulos, David Tomecek, Anne Uhlmann, Aristotle Voineskos, Kun Yang, Neda Jahanshad, Paul M. Thompson, Theo G. M. Van Erp, Jessica A. Turner, Gianfranco Spalletta, Federica Piras
Summary: Converging evidence suggests that schizophrenia (SZ) with primary, enduring negative symptoms represents a distinct entity within the SZ spectrum. In the largest dataset of DSZ and NDSZ, a meta-analysis and mega-analysis were conducted to determine if they differ in terms of cortical morphology. The findings demonstrate that DSZ and NDSZ are characterized by different neuroimaging phenotypes, supporting a nosological distinction between the two.
MOLECULAR PSYCHIATRY
(2023)
Article
Multidisciplinary Sciences
Jessica Royer, Raul Rodriguez-Cruces, Shahin Tavakol, Sara Lariviere, Peer Herholz, Qiongling Li, Reinder Vos de Wael, Casey Paquola, Oualid Benkarim, Bo-yong Park, Alexander J. Lowe, Daniel Margulies, Jonathan Smallwood, Andrea Bernasconi, Neda Bernasconi, Birgit Frauscher, Boris C. Bernhardt
Summary: Multimodal neuroimaging provides a powerful tool to study the structure and function of the human brain at multiple scales. Researchers have developed a framework to investigate the interplay between large-scale spatial trends in brain microstructure and connectivity, offering insights into multiscale brain organization. A multimodal MRI dataset, MICA-MICs, is shared, which includes various imaging modalities and connectomes gathered across multiple parcellation scales, facilitating future research on the coupling between brain microstructure, connectivity, and function.
Article
Anatomy & Morphology
Niharika Gajawelli, Sean C. L. Deoni, Natalie Ramsy, Douglas C. Dean, Jonathan O'Muircheartaigh, Marvin D. Nelson, Natasha Lepore, Olivier Coulon
Summary: This study investigated the development of the central sulcus in children aged 12-60 months, revealing a rightward depth asymmetry at 12 months that gradually disappears between 12 and 24 months, potentially related to the development of language skills.
BRAIN STRUCTURE & FUNCTION
(2021)
Article
Multidisciplinary Sciences
Scinob Kuroki
Summary: Skin covers the whole body, with variations in thickness and distribution of mechanoreceptors across different body parts. The brain cannot fully compensate for this anisotropy, resulting in differences in the representational space of touch depending on the location of the stimulus. Through a study comparing the hand and arm, it was found that perceived motion can differ between these body parts. By presenting touchable motion stimuli using a large-area braille display, a new perceptual illusion was discovered where motion direction perceived on the arm is regionally rotated or flipped. This study highlights the non-uniformity of perceived tactile space and the need for detailed examination.
SCIENTIFIC REPORTS
(2023)
Review
Neurosciences
Jordan DeKraker, Stefan Kohler, Ali R. Khan
Summary: This article discusses the application of surface-based methods in modeling hippocampal folding, allowing interindividual alignment in a 2D space, which helps in detailed morphological characterization and solving the problem of subfield segmentation.
TRENDS IN NEUROSCIENCES
(2021)
Article
Anatomy & Morphology
Michel R. T. Sinke, Willem M. Otte, Daan Christiaens, Oliver Schmitt, Alexander Leemans, Annette van der Toorn, R. Angela Sarabdjitsingh, Marian Joels, Rick M. Dijkhuizen
BRAIN STRUCTURE & FUNCTION
(2018)
Article
Biochemical Research Methods
Oliver Schmitt, Peter Eipert, Sebastian Schwanke, Felix Lessmann, Jennifer Meinhardt, Julia Beier, Kanar Kadir, Adrian Karnitzki, Linda Sellner, Ann-Christin Kluenker, Frauke Russ, Joerg Jenssen
BRIEFINGS IN BIOINFORMATICS
(2019)
Article
Computer Science, Interdisciplinary Applications
Sebastian Schwanke, Joerg Jenssen, Peter Eipert, Oliver Schmitt
Article
Neurosciences
T. Mann, K. Zilles, H. Dikow, A. Hellfritsch, M. Cremer, M. Piel, F. Roesch, A. Hawlitschka, O. Schmitt, A. Wree
Article
Food Science & Technology
Veronica Antipova, Andreas Wree, Carsten Holzmann, Teresa Mann, Nicola Palomero-Gallagher, Karl Zilles, Oliver Schmitt, Alexander Hawlitschka
Article
Anatomy & Morphology
Oliver Schmitt, Peter Eipert, Richard Kettlitz, Felix Lessmann, Andreas Wree
BRAIN STRUCTURE & FUNCTION
(2016)
Article
Anatomy & Morphology
Teresa Mann, Karl Zilles, Felix Klawitter, Markus Cremer, Alexander Hawlitschka, Nicola Palomero-Gallagher, Oliver Schmitt, Andreas Wree
FRONTIERS IN NEUROANATOMY
(2018)
Article
Multidisciplinary Sciences
O. Schmitt, S. Badurek, W. Liu, Y. Wang, G. Rabiller, A. Kanoke, P. Eipert, J. Liu
SCIENTIFIC REPORTS
(2017)
Article
Biochemistry & Molecular Biology
Martin Witt, Rene Thiemer, Anja Meyer, Oliver Schmitt, Andreas Wree
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2018)
Article
Cell Biology
Sarah Joost, Stefan Mikkat, Michael Wille, Antje Schuemann, Oliver Schmitt
Article
Anatomy & Morphology
H. Claassen, O. Schmitt, M. Schulze, A. Wree
Summary: This study classified for the first time the median distance of separation of the deep femoral artery (DFA) from the femoral artery (FA) in relation to the inguinal ligament (IL) in three defined groups. The knowledge of DFA branching pattern is crucial for recent therapy options of cardiac diseases, and the variant topography of the branches of femoral nerve in relation to lateral and medial circumflex femoral arteries was also mentioned.
ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER
(2021)
Article
Biochemical Research Methods
Oliver Schmitt, Christian Nitzsche, Peter Eipert, Vishnu Prathapan, Marc-Thorsten Huett, Claus C. Hilgetag
Summary: Connectomes provide comprehensive descriptions of neural connections, which are crucial for understanding central brain function and peripheral processing of neural signals. This study examines detailed connectomes with edge weighting and orientation properties, and investigates diffusion-reaction models to study dynamic concentration patterns in control and lesioned connectomes. The implementation of reaction-diffusion systems in the neuroVIISAS framework allows for the study of empirical connectomes and specific network models.
PLOS COMPUTATIONAL BIOLOGY
(2022)
Article
Neurosciences
Alexander Hawlitschka, Carsten Holzmann, Sarah Witt, Juliane Spiewok, Anne-Marie Neumann, Oliver Schmitt, Andreas Wree, Veronica Antipova
Article
Biochemistry & Molecular Biology
Annett Markus-Koch, Oliver Schmitt, Susanne Seemann, Jan Lukas, Dirk Koczan, Mathias Ernst, Georg Fuellen, Andreas Wree, Arndt Rolfs, Jiankai Luo
CELLULAR & MOLECULAR BIOLOGY LETTERS
(2017)
Article
Behavioral Sciences
Veronica A. Antipova, Carsten Holzmann, Oliver Schmitt, Andreas Wree, Alexander Hawlitschka
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2017)