Schizophrenia in the Spectrum of Gene-Stress Interactions: The FKBP5 Example

FKBP5 polymorphism is associated with major depression but not with bipolar disorder

(2014) Aleksandra Szczepankiewicz et al.   JOURNAL OF AFFECTIVE DISORDERS

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice

(2014) Katharina Gapp et al.   NATURE NEUROSCIENCE

Identifying Gene-Environment Interactions in Schizophrenia: Contemporary Challenges for Integrated, Large-scale Investigations

(2014)   SCHIZOPHRENIA BULLETIN

H3K27me and PRC2 transmit a memory of repression across generations and during development

(2014) L. J. Gaydos et al.   SCIENCE

FKBP5 as a possible moderator of the psychosis-inducing effects of childhood trauma

(2013) Dina Collip et al.   BRITISH JOURNAL OF PSYCHIATRY

Moderating role of FKBP5 genotype in the impact of childhood adversity on cortisol stress response during adulthood

(2013) Arlette F. Buchmann et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Paternal Stress Exposure Alters Sperm MicroRNA Content and Reprograms Offspring HPA Stress Axis Regulation

(2013) A. B. Rodgers et al.   JOURNAL OF NEUROSCIENCE

FKBP5 Genotype and Structural Integrity of the Posterior Cingulum

(2013) Negar Fani et al.   NEUROPSYCHOPHARMACOLOGY

Stress-System Genes and Life Stress Predict Cortisol Levels and Amygdala and Hippocampal Volumes in Children

(2013) David Pagliaccio et al.   NEUROPSYCHOPHARMACOLOGY

Stress and neurodevelopmental processes in the emergence of psychosis

(2013) C.W. Holtzman et al.   NEUROSCIENCE

A systematic review of the activity of the hypothalamic–pituitary–adrenal axis in first episode psychosis

(2013) Susana Borges et al.   PSYCHONEUROENDOCRINOLOGY

The three-hit concept of vulnerability and resilience: Toward understanding adaptation to early-life adversity outcome

(2013) Nikolaos P. Daskalakis et al.   PSYCHONEUROENDOCRINOLOGY

The Social Defeat Hypothesis of Schizophrenia: An Update

(2013) Jean-Paul Selten et al.   SCHIZOPHRENIA BULLETIN

Allele-specific epigenetic modification: a molecular mechanism for gene–environment interactions in stress-related psychiatric disorders?

(2013) Torsten Klengel et al.   Epigenomics

FKBP5 and Attention Bias for Threat

(2013) Negar Fani et al.   JAMA Psychiatry

Interaction Between FKBP5 and Childhood Trauma and Risk of Aggressive Behavior

(2012) Laura Bevilacqua   ARCHIVES OF GENERAL PSYCHIATRY

FKBP5and emotional neglect interact to predict individual differences in amygdala reactivity

(2012) M. G. White et al.   GENES BRAIN AND BEHAVIOR

Testing the cumulative stress and mismatch hypotheses of psychopathology in a rat model of early-life adversity

(2012) Nikolaos P. Daskalakis et al.   PHYSIOLOGY & BEHAVIOR

Hippocampal volume as marker of daily life stress sensitivity in psychosis

(2012) D. Collip et al.   PSYCHOLOGICAL MEDICINE

Genetic association of FKBP5 and CRHR1 with cortisol response to acute psychosocial stress in healthy adults

(2012) Pamela Belmonte Mahon et al.   PSYCHOPHARMACOLOGY

Interaction ofFKBP5Gene Variants and Adverse Life Events in Predicting Depression Onset: Results From a 10-Year Prospective Community Study

(2011) Petra Zimmermann et al.   AMERICAN JOURNAL OF PSYCHIATRY

City living and urban upbringing affect neural social stress processing in humans

(2011) Florian Lederbogen et al.   NATURE

Moderation of Adult Depression by a Polymorphism in the FKBP5 Gene and Childhood Physical Abuse in the General Population

(2011) Katja Appel et al.   NEUROPSYCHOPHARMACOLOGY

Association of FKBP5, COMT and CHRNA5 polymorphisms with PTSD among outpatients at risk for PTSD

(2011) Joseph A. Boscarino et al.   PSYCHIATRY RESEARCH

Replication in two independent population-based samples that childhood maltreatment and cannabis use synergistically impact on psychosis risk

(2011) M. Konings et al.   PSYCHOLOGICAL MEDICINE

Epigenetic Transmission of the Impact of Early Stress Across Generations

(2010) Tamara B. Franklin et al.   BIOLOGICAL PSYCHIATRY

Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses

(2010) Tim F. Oberlander et al.   Epigenetics

Neuropsychiatric Disorders in Cushing’s Syndrome

(2010) Alberto M. Pereira et al.   NEUROENDOCRINOLOGY

Interaction of FKBP5 with Childhood Adversity on Risk for Post-Traumatic Stress Disorder

(2010) Pingxing Xie et al.   NEUROPSYCHOPHARMACOLOGY

The environment and susceptibility to schizophrenia

(2010) Alan S. Brown   PROGRESS IN NEUROBIOLOGY

FKBP5 and resistant attachment predict cortisol reactivity in infants: Gene–environment interaction

(2010) Maartje P.C.M. Luijk et al.   PSYCHONEUROENDOCRINOLOGY

Animal models for depression and the mismatch hypothesis of disease

(2010) Mathias V. Schmidt   PSYCHONEUROENDOCRINOLOGY

Higher cortisol levels are associated with smaller left hippocampal volume in first-episode psychosis

(2010) Valeria Mondelli et al.   SCHIZOPHRENIA RESEARCH

Evidence for an Interaction Between Familial Liability and Prenatal Exposure to Infection in the Causation of Schizophrenia

(2009) Mary C. Clarke et al.   AMERICAN JOURNAL OF PSYCHIATRY

Schizophrenia in the Offspring of Antenatally Depressed Mothers in the Northern Finland 1966 Birth Cohort: Relationship to Family History of Psychosis

(2009) Pirjo Mäki et al.   AMERICAN JOURNAL OF PSYCHIATRY

The mechanism of life-threatening water imbalance in schizophrenia and its relationship to the underlying psychiatric illness

(2009) Morris B. Goldman   BRAIN RESEARCH REVIEWS

Magnetic resonance imaging studies in bipolar disorder and schizophrenia: meta-analysis

(2009) D. Arnone et al.   BRITISH JOURNAL OF PSYCHIATRY

Vulnerability genes or plasticity genes?

(2009) J Belsky et al.   MOLECULAR PSYCHIATRY

Effects of stress throughout the lifespan on the brain, behaviour and cognition

(2009) Sonia J. Lupien et al.   NATURE REVIEWS NEUROSCIENCE

Epigenetic Mediation of Environmental Influences in Major Psychotic Disorders

(2009) B. P. F. Rutten et al.   SCHIZOPHRENIA BULLETIN

Stress and the Hypothalamic Pituitary Adrenal Axis in the Developmental Course of Schizophrenia

(2008) Elaine Walker et al.   Annual Review of Clinical Psychology

Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls

(2008) Marcus Ising et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Association of FKBP5 Polymorphisms and Childhood Abuse With Risk of Posttraumatic Stress Disorder Symptoms in Adults

(2008) Elisabeth B. Binder   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A randomised controlled study of risperidone and olanzapine for schizophrenic patients with neuroleptic-induced acute dystonia or parkinsonism

(2008) HY Chan et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Family-based association of FKBP5 in bipolar disorder

(2008) V L Willour et al.   MOLECULAR PSYCHIATRY

Gene-Environment Interactions in Schizophrenia: Review of Epidemiological Findings and Future Directions

(2008) J. van Os et al.   SCHIZOPHRENIA BULLETIN

Psychosocial Stress and Psychosis. A Review of the Neurobiological Mechanisms and the Evidence for Gene-Stress Interaction

(2008) R. van Winkel et al.   SCHIZOPHRENIA BULLETIN

Fundamental aspects of the impact of glucocorticoids on the (immature) brain

(2008) Danielle L. Champagne et al.   Seminars in Fetal & Neonatal Medicine

Amygdala Volume in Patients Receiving Chronic Corticosteroid Therapy

(2007) E. Sherwood Brown et al.   BIOLOGICAL PSYCHIATRY