Article
Materials Science, Multidisciplinary
Chaoyi Teng, Raynald Gauvin, Yongzhe Wang
Summary: This study proposes new computation methods for addressing the challenges in low-voltage SEM imaging and X-ray microanalysis. The analytical sensitivity for X-ray microanalysis is thoroughly studied through experiments and simulations.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Chemistry, Analytical
Chaoyi Teng, Raynald Gauvin
Summary: The f-ratio method is a new quantitative X-ray microanalysis method that calculates the f-ratio with characteristic X-ray intensities and uses Monte Carlo simulation to establish the theoretical relation between system composition and the f-ratio. Experimental results show that the f-ratio model can accurately analyze standard mineral samples.
Article
Chemistry, Physical
Nebahat Aral, Maria Amor Duch, F. Banu Nergis, Cevza Candan
Summary: Experimental study shows that materials with nanoparticles provide higher radiation protection compared to samples with micro sized powders, even with the same weight ratios of additives. Additionally, there is a larger difference in radiation attenuation between micro and nano sized materials at low energies, which decreases at high energies. Comparing simulation and experimental results, it is found that the experimental data aligns with simulation results as the average particle size decreases. Hence, lightweight materials can be developed using nanoparticles to achieve more uniform structures with the same level of protection.
RADIATION PHYSICS AND CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Ehsan Nazemi, Nathanael Six, Domenico Iuso, Bjorn De Samber, Jan Sijbers, Jan De Beenhouwer
Summary: The study utilized Monte Carlo simulations to model the FleXCT system, improving the accuracy of research on beam hardening and scattering artifacts.
APPLIED SCIENCES-BASEL
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Maritina Rouchota, George Loudos, George C. Kagadis
Summary: A simulation platform has been developed to predict contrast induction and minimum detectable concentration of Gold Nanoparticles on X-ray systems, applicable to preclinical and clinical studies. This model could facilitate the deployment of GNPs in radiology imaging.
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
(2021)
Article
Optics
Ruoyu Chen, Shanbao Tong, Peng Miao
Summary: This study proposes a deep-learning-based strategy for high spatiotemporal resolution three-dimensional (3D) reconstruction from a single transilluminated laser speckle contrast image, providing more structural and functional details without multifocus two-dimensional (2D) imaging or 3D optical imaging with point/line scanning. The method utilizes convolution of vessel masks with depth-dependent point spread functions (PSF) to generate a large training dataset, and employs UNet and ResNet for deblurring and depth estimation. The blood flow in the reconstructed 3D vessels is estimated by a depth-dependent contrast model. The proposed method achieves high-fidelity structural reconstruction with a depth-independent estimation of blood flow, and is suitable for real-time monitoring of thick tissue and the diagnosis of vascular diseases.
Article
Engineering, Biomedical
Yanqi Huang, Kai Yang, Youfang Lai, Huan Liu, Chenyang Shen, Yuncheng Zhong, Yiping Shao, Xinhua Li, Bob Liu, Xun Jia
Summary: The study reports recent progress using photon counting detection technique to demonstrate the potential feasibility of scattered x-ray imaging for real-time guidance in lung cancer radiotherapy. Correction of the raw images converted them into actual Compton attenuation coefficient images, with a strong linear relationship between x-ray scattering image intensity and Compton scattering attenuation coefficient. The study also showed that image resolution is dependent on imaging system geometry, with resolution increasing with reduced source to object distance and increased collimator height.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Multidisciplinary Sciences
Isabela C. Moraes, Dean Hesterberg, Fernando A. Bacchim Neto, Nathaly L. Archilha, Carlos A. Perez, Maria Victoria A. Araujo, Talita R. Ferreira
Summary: This study aims to develop methods to reduce the impact of synchrotron X-ray radiation on root growth during in vivo imaging. The results suggest that monochromatic radiation at the highest suitable energy and controlling the rotation axis of off-centered roots can diminish radiation dose during in vivo imaging of plant roots.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Inorganic & Nuclear
R. Figueroa, F. Geser, J. Lopez-Correa, F. Malano, M. Valente
Summary: The traditional X-ray tube design has limitations in optimizing high incident fluence spatial concentration, while a novel X-ray tube design is capable of producing a convergent X-ray beam, improving overall performance and spatial resolution for applications like X-ray fluorescence imaging. This study suggests the feasibility of the proposed design for achieving high fluence concentration, particularly useful for applications such as tumor targeting by X-ray fluorescence imaging with high atomic number nanoparticle infusion.
APPLIED RADIATION AND ISOTOPES
(2021)
Article
Chemistry, Physical
Pavel Novotny
Summary: This paper investigates the possibility of characterizing radioactive samples in detail using X-ray fluorescence analysis, as well as demonstrates the application of this measurement for improving the accuracy of beta spectra calculation in the MCNPX software package. The results show that high-resolution XRF 2D scanning can reduce uncertainties in Monte Carlo simulations.
RADIATION PHYSICS AND CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Fernando T. Tanouye, Jozismar R. Alves, Francesco Spinozzi, Rosangela Itri
Summary: In this study, protein interactions were investigated using in-solution small angle X-Ray scattering (SAXS) experiments and Monte Carlo (MC) simulations under different conditions. The analysis of experimental data using the HSDY/RPA model combined with MC simulations showed limitations in describing the protein-protein pair potential for highly concentrated systems at low ionic strength. SAXS/MC results revealed that lysozyme concentrations between 2 and 20 mg/mL exhibited similar protein-protein pair potentials, with a surface net charge of around 7 e, protein diameter of 28 Å, attractive well potential decay range of 3 Å, and a depth varying from 1 to 5 kBT depending on temperature and salt addition. Additionally, a novel method combining SAXS with MC simulations was proposed to overcome the limitations of closure relationships in analyzing interacting protein SAXS data.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Maria A. Kolyvanova, Alexandr V. Belousov, Grigorii A. Krusanov, Alexandra K. Isagulieva, Kirill V. Morozov, Maria E. Kartseva, Magomet H. Salpagarov, Pavel V. Krivoshapkin, Olga V. Dement'eva, Victor M. Rudoy, Vladimir N. Morozov
Summary: This study investigated the ability of different high atomic number metal and metal oxide nanoparticles to enhance absorbed dose, with gold showing the highest dose enhancement factor and HfO2 and Ta2O5 being the most versatile in terms of coordinate regions. The findings underscore the importance of carefully planning radiation exposure when high-Z nanoparticles are present.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Physical
Brais Rodriguez-Garcia, Manuel M. Pineiro, Martin Perez-Rodriguez
Summary: In this study, we investigate the behavior of noble gases (He, Ne, Ar, and Kr) within a hydroquinone clathrate (HQC) using all-atom molecular dynamics simulations. Our results show that larger elements of the same group cannot fit inside the HQC cavities. By applying the umbrella sampling technique, we obtain the inter-cage transition barriers for these gases at 310 K and 0.1 MPa, which are crucial for determining their diffusion behavior: 1192, 2204, 6450, and 10 730 kJ mol(-1) for He, Ne, Ar, and Kr, respectively. These energy barriers exhibit a linear relationship with atomic radii (sigma), as demonstrated by the CH4 simulation.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Article
Physics, Multidisciplinary
Yoshiyuki Hirano, Seiichi Yamamoto, Naritoshi Kawamura, Kazuhiko Ninomiya
Summary: Studying the imaging of positrons can be done by calculating the energy spectrum and position distributions of annihilation radiations and bremsstrahlung x-rays. The bremsstrahlung x-rays mainly come from high-energy decayed positrons, while a sharp peak at 511 keV is observed in the energy spectrum of annihilation radiations. The position distribution of bremsstrahlung x-rays is similar to the Cerenkov-light position distribution, and imaging bremsstrahlung x-rays from decayed positrons is a promising method for QA of positive muons.
Article
Engineering, Biomedical
L. Quenot, E. Brun, J. M. Letang, M. Langer
Summary: X-ray phase contrast imaging (PCI) is a group of highly sensitive imaging techniques that allows imaging at scales ranging from nanoscopic to medical, with speckle-based imaging rapidly developing due to its experimental simplicity and capability to retrieve sample properties; this study evaluates different simulation codes, with strong similarity found between simulated and experimental data, and discusses the validity and applicability of each approach.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
