Article
Chemistry, Analytical
Thaiane Nolasco da Silva, Diego B. Batista, Bernardo Ferreira Braz, Aderval S. Luna, Ricardo Erthal Santelli, Marcos Antonio dos Santos Fernandez, Jefferson S. de Gois
Summary: This work describes the development of microwave-assisted digestion methods for the determination of Cu and Sn in antifouling paints by ICP OES. The optimal conditions were determined by optimizing factors such as sample mass and solutions of HNO3, HF, and HCl. The microwave digestion-assisted ICP-OES method showed better performance compared to dry ashing with a muffle furnace and laser ablation-ICP-MS.
Article
Environmental Sciences
Ghanim Al-Thani, Adel Ehab Ibrahim, Mohammed Alomairi, Baher I. Salman, Mostafa M. Hegazy, Ahmed Al-Harrasi, Sami El Deeb
Summary: The use of weight loss herbal preparations is increasing due to the consumption of high-calorie junk food. However, the regulations governing the quality control of these products may be minimal. This study investigated the elemental contents in these products and found that some macro-elements were present at safe levels, while some micro-elements and other elements showed concerning levels. Stricter surveillance of herbal products is necessary.
Article
Chemistry, Applied
Jian Lee, Ye-Seul Park, Hwa-Jeong Lee, Yong Eui Koo
Summary: A novel method using diluted nitric acid and hydrogen peroxide for microwave-assisted digestion of milk samples was developed for elemental analysis. The optimized conditions resulted in accurate detection of various elements in milk samples.
Article
Materials Science, Multidisciplinary
Natalia A. Korotkova, Vasilisa B. Baranovskaya, Kseniya Petrova
Summary: In this article, an analytical procedure for the analysis of waste Sm-Co magnets was developed using ICP-MS and ICP-OES. The experimental parameters related to microwave digestion and acid concentrations were optimized. The matrix effect on the ICP-MS analysis and optimal instrumental parameters were investigated. The proposed method was validated through recovery tests and inter-method experiments.
Article
Spectroscopy
Gustavo R. Bitencourt, Sindy R. Krzyzaniak, Leticia S. F. Pereira, Cezar A. Bizzi, Erico M. M. Flores, Paola A. Mello
Summary: A method was developed for the determination of elemental contaminants and metal catalyst residues in carbon nanotubes by ICP OES. The method optimized a greener digestion protocol for sample preparation, and achieved complete digestion of up to 100 mg of CNT. The proposed method provided reliable determinations and can be used for routine quality control of metal catalyst residues or impurities in CNTs.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2023)
Article
Pharmacology & Pharmacy
S. M. Nandanwadkar, P. J. Hurkadale, C. M. Bidikar, M. M. Godbole
Summary: Research indicates that phytopigments derived from plants are ideal substitutes for synthetic dyes, with a focus on screening their composition using ICP-OES technology to ensure their safety for human consumption. Additionally, these natural pigments are rich in flavonoids and possess strong antioxidant properties. Therefore, utilizing these natural pigments as food additives may be safer and more reliable.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Gaurav K. Deshwal, Laura G. Gomez-Mascaraque, Mark Fenelon, Thom Huppertz
Summary: Microwave digestion is a quicker method with lower acid volume compared to dry and wet digestion for mineral analysis. In this study, the three digestion methods were compared for measuring major and trace minerals in cheese samples. The results showed strong correlation between microwave digestion and dry and wet digestion for major minerals, but potential measurement errors for minor minerals.
Article
Chemistry, Multidisciplinary
Mohamed A. Gab-Allah, Adel B. Shehata
Summary: A new method based on microwave-assisted digestion (MW-AD) was developed for efficient determination of iron, nickel, and vanadium in crude oil samples, with optimized conditions yielding satisfactory results. The method was successfully validated through spiked sample analysis, demonstrating good recovery and precision.
Article
Chemistry, Analytical
Herick Macedo Santos, Julymar Marcano Higuera, Ana Rita Araujo Nogueira
Summary: Multi-energy calibration (MEC) and high matrix introduction (HMI) system were used to directly analyze simulated gastrointestinal chyme and estimate the bioaccessibility of essential elements and As in shrimp. The results showed that the proposed procedures were accurate and efficient, with no significant differences compared to the reference method. Heat treatment increased the bioaccessibility of Cu and Fe, but decreased the bioaccessibility of Zn. The procedures provide simplicity and high sample throughput for elemental bioaccessibility studies.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2023)
Article
Chemistry, Applied
Andrey Shishov, Artur Gerasimov, Andrey Bulatov
Summary: Research found that carboxylic acid precursor in deep eutectic solvents is crucial for effective metal separation. Solvent synthesized from deep eutectic solvents provides high extraction recovery of metals. Control of temperature and time can effectively separate metals in plant samples.
Article
Chemistry, Analytical
Roman Grimmig, Simon Lindner, Philipp Gillemot, Markus Winkler, Steffen Witzleben
Summary: By analyzing a dataset of several hundred used engine oils, the feasibility of using the machine learning system XGBoost to predict the identity and overall condition of an unknown combustion engine was further investigated. A maximum accuracy of 89.6% in predicting the engine type, a mean error of less than 10% of the observed timeframe in predicting the oil running time, and less than 4% for the total engine running time were achieved based purely on common oil check data. Our results demonstrate that both the identification of an unknown engine and a lifetime assessment can be performed for a first estimation of the actual sample without requiring meticulous documentation.
Article
Chemistry, Analytical
John T. Sloop, Sean C. Allen, Jake A. Carter, George L. Donati, Bradley T. Jones
Summary: A two-point calibration method based on SDA was used to accurately analyze complex-matrix samples, requiring only two calibration solutions per sample. The method calculates analyte concentration by utilizing the slope and intercept of an analyte vs. IS plot, the analyte concentration in the standard added to S1, and the signal intensity of the IS in S1. This approach yielded similar or superior results compared to EC, IS, and SA methods, without the need for mixing solutions or additional equipment modifications.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Natalia Manousi, Eleni Isaakidou, George A. Zachariadis
Summary: This study developed a simple and rapid ICP-OES method to determine 17 metals in packaged spices. The digestion process played a crucial role and the method was successfully applied to 22 commercially available spices.
APPLIED SCIENCES-BASEL
(2022)
Article
Chemistry, Applied
Luciane B. Oliveira, Joelem C. de Melo, Elane S. da Boa Morte, Raildo M. de Jesus, Leonardo S. G. Teixeira, Maria Gracas A. Korn
Summary: The study evaluated the determination of macro-and microelements in chocolate bars using microwave-induced plasma optical emission spectrometry (MIP OES) after microwave-assisted sample digestion. The optimized sample digestion conditions were successfully applied for routine analysis of chocolate bars, showing a wide range of element concentrations. The combination of microwave-assisted acid digestion with MIP OES technique proved to be effective for multi-element determination in chocolate bars.
Article
Chemistry, Applied
Onkar Apine, Sumit Parit, Vikramasinh Kanugade, Santosh Sutar, Sanjay Mahajani, Jyoti Jadhav
Summary: In this study, an integrated sample preparation and analytical method was developed for the determination of copper (Cu), iron (Fe), and manganese (Mn) in non-centrifugal sugars (NCS). Response surface methodology and central composite design were employed to optimize the microwave-assisted digestion, and inductively coupled plasma optical emission spectrometry (ICP-OES) was used for quantification. The method showed good precision and accuracy, providing a reliable approach to assess the nutritional value of NCS samples.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Chemistry, Analytical
Mariele S. Nascimento, Gabriel T. Druzian, Leticia S. F. Pereira, Marcia F. Mesko, Rochele S. Picoloto, Paola A. Mello, Erico M. M. Flores
Summary: A microwave-assisted extraction method was developed for determining Cl, Br, and I in medicinal plants. The method showed accurate and reliable results compared to a reference method using ICP-MS. Care should be taken to control the carbon content to avoid interference.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2022)
Article
Food Science & Technology
Greice Carine Raddatz, Vitor Ramires Fonseca, Alexandre Jose Cichoski, Leila Queiroz Zepka, Eduardo Jacob-Lopes, Paulo Cezar Bastianello Campagnol, Roger Wagner, Edson Irineo Muller, Erico Marlon de Moraes Flores, Cristiane de Bona da Silva, Cristiano Ragagnin de Menezes
Summary: The study found that adding red onion peel extract can increase the survival rate of probiotics under simulated gastrointestinal conditions and thermal treatments, with the best effect seen in microparticles containing 20% extract. Under storage conditions at 25 degrees Celsius, the formulations with 5% and 20% extract performed better, and all microparticle formulations remained stable at -18 degrees Celsius for 90 days.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Green & Sustainable Science & Technology
Daniel Santos, Karen Giacobe, Carolina M. Silva, Loisleini F. Saldanha, Ayrton F. Martins, Erico M. M. Flores, Cezar A. Bizzi
Summary: Lignocellulosic materials are a promising alternative source for producing liquid biofuel and fine chemicals with low environmental impact, but they can be contaminated with metals and nonmetals. This study successfully utilized ultrasound energy to remove impurities from sugarcane straw, increasing fermentable sugars' production and demonstrating high efficiency in demineralization. The scaling up experiments also showed the potential applicability of ultrasound-assisted procedure for large-scale demineralization.
Article
Environmental Sciences
Altevir Rossato Viana, Bruna Godoy Noro, Daniel Santos, Katianne Wolf, Yasmin Sudatti Das Neves, Rafael Noal Moresco, Aline Ferreira Ourique, Erico Marlon Moraes Flores, Cristiano Rodrigo Bohn Rhoden, Luciana Maria Fontanari Krause, Bruno Stefanello Vizzotto
Summary: This study investigated the phytochemical compositions and biological activities of Vassobia breviflora extract. The extract exhibited excellent antioxidant and antimicrobial activities, as well as cytotoxic effects against various tumor cells. Moreover, it also increased the production of reactive oxygen species.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES
(2023)
Article
Chemistry, Analytical
Felipe A. Silva, Beatriz R. Rigui, Cristian R. Andriolli, Erico M. M. Flores, Paola A. Mello, Rochele S. Picoloto
Summary: A miniaturized liquid-liquid extraction (LLE) method was proposed for pre-concentration of Na, K, Ca, and Mg in crude oil. The method showed no statistical difference compared to the reference values, with relative standard deviations lower than 6%. The proposed miniaturized LLE method presents several advantages, such as ease-of-use, high throughput, and low limits of quantification, making it an environmentally friendly and cost-effective alternative for routine analyses.
Article
Chemistry, Analytical
Jaime S. Mandlate, Alessandra S. Henn, Paola A. Mello, Erico M. M. Flores, Juliano S. Barin, Fabio A. Duarte
Summary: A simple and fast sample preparation method called microwave-induced combustion in disposable vessels (MIC-DV) was developed for Cl and S determination in crude oil using ICP-OES. The method allows efficient digestion of up to 10 mg of crude oil per cycle, reaching a total sample mass of 50 mg.
ANALYTICA CHIMICA ACTA
(2023)
Article
Engineering, Chemical
Andressa Fernandes Leal, Paulo Carteri Coradi, Rosana dos Santos Moraes, Edson Mueller, Paulo Eduardo Teodoro, Larissa Pereira Ribeiro Teodoro, Dagila Melo Rodrigues
Summary: This study aimed to evaluate the effects of drying-tempering time and air temperature on the quality of polished rice. The results showed that the increase in temperature and prolonged drying-tempering time adversely affected the physical, physicochemical, and morphological qualities of the rice. It was concluded that drying technologies with tempering periods should be designed with a maximum temperature of 75 degrees Celsius and drying time not exceeding 8 hours for optimal rice quality.
Article
Construction & Building Technology
Pedro Orlando Borges de Almeida Junior, Silvio Lisboa Schuster, Cleber Faccin, Pablo Menezes Vestena, Pedro Schmidt Ilha, Gustavo Menegusso Pires, Edson Irineu Mueller, Deividi da Silva Pereira, Luciano Pivoto Specht
Summary: This study evaluates the rheological, permanent deformation and fatigue tests to calibrate the recovery procedure in the rotary evaporator. The results indicate that the chemical FTIR test is not sensitive in detecting the presence of residual solvent in the bituminous materials.
ROAD MATERIALS AND PAVEMENT DESIGN
(2023)
Article
Environmental Sciences
Jorge Osorio-Martinez, Luis F. F. Silva, Erico M. M. Flores, Gabriel T. T. Druzian, Jesus Olivero-Verbel
Summary: This study assessed the concentrations and toxicity of potentially toxic elements (PTEs) in urban dust from Barranquilla, Colombia. The results showed that the PTEs in the dust had negative effects on the physiological parameters of Caenorhabditis elegans, indicating that it can be used as a sensitive organism for warning systems related to biota risks associated with air pollution.
WATER AIR AND SOIL POLLUTION
(2023)
Article
Multidisciplinary Sciences
Rosana Santos de Moraes, Paulo Carteri Coradi, Marcela Trojahn Nunes, Marisa Menezes Leal, Edson Irineu Muller, Paulo Eduardo Teodoro, Erico Marlon Moraes Flores
Summary: Drying rice in a silo-dryer-aerator using single-layer loading at low temperatures resulted in uniform drying. This study evaluated the physical, physicochemical, and morphological quality of rice grain cultivars in the lower and upper layers of the silo-dryer-aerator. The results showed that drying rice in silo-dryer-aerator attenuated the moisture diffusivity in the grains and preserved the physicochemical constituents and morphology of starch, especially in the lower layers throughout the 2-month drying. The Guri INTA and BRS Pampeira cultivars exhibited the highest resistance to drying and had the most uniform final quality.
Article
Chemistry, Analytical
Jussiane S. S. Silva, Graciela M. M. Heidrich, Bruno O. O. Poletto, Jose N. G. Paniz, Valderi L. L. Dressler, Erico M. M. Flores
Summary: A direct solid sampling method using ETV-ICP-MS was developed for determining mercury in bioresorbable calcium phosphate-based materials. The method involved fast sample heating with a halogen lamp, followed by vaporization and cooling steps. Mercury vaporized at a low temperature and did not co-vaporize the main matrix. External calibration using aqueous solutions was used for quantification. The method showed good accuracy, precision, and sample throughput, making it suitable for routine analyses.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2023)
Article
Chemistry, Analytical
Gustavo Rossato Bitencourt, Fabio Andrei Duarte, Valderi Luiz Dressler, Rodrigo Cordeiro Bolzan, Erico Marlon de Moraes Flores, Paola Azevedo Mello
Summary: A single method using chemical vapor generation coupled with microwave-induced plasma optical emission spectrometry was developed for the determination of As and Hg in dietary supplements. The method complied with the maximum concentration requirements set by the United States Pharmacopeia and showed no statistical difference compared to comparative methods. The proposed method can be considered an alternative for the quality control of As and Hg in dietary supplements.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2023)
Article
Food Science & Technology
Vanessa Bordin Viera, Natieli Piovesan, Renius De Oliveira Mello, Juliano Smanioto Barin, Aline De Oliveira Fogaca, Cezar Augusto Bizzi, Erico Marlon De Moraes Flores, Ana Carolina Dos Santos Costa, Diego Elias Pereira, Juliana Kessia Barbosa Soares, Ernesto Hashime Kubota
Summary: This study determined the antioxidant activity of red onion peel extract using ultrasound extraction, and found that different ultrasound power and solvent concentration had varying effects on different antioxidant indicators.
JOURNAL OF CULINARY SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Gabriel T. Druzian, Mariele S. Nascimento, Rochele S. Picoloto, Marcia F. Mesko, Erico M. M. Flores, Paola A. Mello
Summary: A method for determining sub-ppb levels of mercury in crude oil using cold vapor generation inductively coupled plasma mass spectrometry (CV-ICP-MS) was developed by optimizing the operational parameters for crude oil digestion and evaluating the accuracy of the method. The optimized conditions allowed for the complete digestion of up to 1.2 g of crude oil and achieved a very low limit of detection.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2022)
Article
Agronomy
Caroline Pagnossim Boeira, Deborah Cristina Barcelos Flores, Bruna Nichelle Lucas, Daniel Santos, Erico Marlon Moraes Flores, Frederico Luiz Reis, Liziane Maria Barassuol Morandini, Ademir Farias Morel, Claudia Severo da Rosa
Summary: This study investigated the feasibility of ultrasound-assisted extraction of antioxidant compounds from corn stigma and optimized the extraction conditions. The results showed that ultrasound-assisted extraction increased the antioxidant activity and reduced the extraction time. The characterized extract exhibited promising antifungal and antibacterial activities.
Article
Chemistry, Analytical
Michel Rocha Baqueta, Augusto Cesar Costa-Santos, Ana Paula Rebellato, Gisele Marcondes Luz, Juliana Azevedo Lima Pallone, Federico Marini, Alexsandro Lara Teixeira, Douglas N. Rutledge, Patricia Valderrama
Summary: This study reports the essential element composition of new Brazilian Canephora coffees and applies chemometric tools for analysis. The results demonstrate the suitability of this method for origin and species discrimination based on the inorganic fraction of coffee.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mengjie Li, Jiapeng Wang, You Zhou, Yang Chen, Lingying Xia
Summary: A novel photoelectrochemical biosensor based on gold nanoparticles and specific structures was developed for highly sensitive detection of mercury ion. The multiple sandwich structures hindered electron supply and light harvesting, resulting in a weakened PEC signal, while the specific structures extinguished the PEC signal, enabling quantitative detection of Hg2+. The sensor exhibited high selectivity and stability, with potential applications in environmental detection, biological analysis, and medical research.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mohamed A. Korany, Rasha M. Youssef, Marwa A. A. Ragab, Mostafa A. Afify
Summary: A stability-indicating fit-for-purpose method was developed for the determination of HC, TL, and PS in syrup dosage form. The method successfully separated CL from THY and quantified the analytes using HPLC-DAD. The robustness of the method was assessed through statistical analysis and self-validation.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Lingling Lin, Minyu Li, Ping Li, Chenqing Ye, Huanglong Zhuang, Shaohuang Weng, Feng Chen
Summary: This study developed a highly sensitive and selective electrochemical sensor for simultaneous detection of dopamine and uric acid. The sensor exhibited excellent anti-interference and stability, and could accurately measure dopamine and uric acid in human urine samples.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Peifang Chen, Caiyun Jiang, Zhouping Wang, Hong-zhen Lian, Xiaoyuan Ma
Summary: In this study, a high-performance SERS-active aptasensor was successfully developed for the quantitative analysis of AFB1 in cereal grains, which is of great significance in the field of food safety.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
E. Abas, C. Marina-Montes, C. Perez-Marin, J. Puimedon, J. Anzano
Summary: This study conducted a comprehensive measurement of natural and anthropogenic radionuclides in soil, water, and air in different locations around Deception Island in Antarctica. The results revealed significant levels of 210Pb and anthropogenic 137Cs in soil samples near old human settlements and facilities, as well as detectable levels of 137Cs and 60Co in water samples from old hunting areas. The findings also suggested potential resuspension processes based on higher-than-expected air quality results.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Joao Franciso Allochio, Nayara A. dos Santos, Nathalia dos S. Conceicao, Clara S. D. Baptista, Keyller B. Borges, Valdemar Lacerda Jr, Wanderson Roma
Summary: This study developed a fiber spray ionization mass spectrometry (FSI-MS) method, which shows great potential in detecting illicit drugs. Compared with paper spray ionization mass spectrometry (PSI-MS), FSI-MS demonstrates higher sensitivity in COC detection.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Dina A. Ahmed, Ola G. Hussein, Mamdouh R. Rezk, Mohamed Abdelkawy, Yasmin Rostom
Summary: The main goal of this study was to develop two green chromatographic techniques, HPLC and TLC, for the determination of alcaftadine (ALF) in pharmaceutical formulation and biological samples. The developed HPLC technique showed high efficiency and minimal environmental impact, successfully identifying ALF in the presence of its degradate. The TLC method provided a stability indicating study for ALF and was determined to be safe, green, and eco-friendly.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Abdullah Taner Bisgin
Summary: A green, speedy, and handy method for separation and determination of four commonly used food colorants was established using vortex assisted sequential-simultaneous liquid phase micro-extraction (VA-SS-LPME). The method does not require any instrumental chromatographic techniques. The procedure includes sequential separation steps using different extractants and simultaneous UV-vis spectrophotometric determination steps. The method is environmentally friendly and applicable for determination of colorants in food and pharmaceuticals.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Yifan Zhang, Tong Zhang, Wenjing Ba, Li Liu, Yuan Rao, Xiaodan Zhang, Hanhan Zhang, Xiu Jin
Summary: This paper proposes a novel spectral transfer modelling method based on neural network architecture searching for the asymptomatic prediction of Akizuki pear cork spot disorder. The experiments show that the model by this method is more effective, achieving an accuracy of 82.61%.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Krzysztof Greda, Maja Welna, Anna Szymczycha-Madeja, Pawel Pohl
Summary: For the first time, a dispersive micro-solid phase extraction (D-mu SPE) based on graphene oxide was used for the ultrasensitive determination of Cd. With this method, Cd can be efficiently extracted from a mixture of alkali and alkaline earth metals without the need for an elution step. The combination of D-mu SPE and SAGD OES significantly reduces matrix effects and improves the tolerance of Cd to alkali metals. The method shows simplicity in the measurement system and the commercially available nanosorbent used.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
P. K. Fathima Anjila, G. R. Tharani, Anand Sundaramoorthy, Venkat Kumar Shanmugam, Karthikeyan Subramani, Shanmugavel Chinnathambi, Ganesh N. Pandian, Vimala Raghavan, Andrews Nirmala Grace, Singaravelu Ganesan, Mangaiyarkarasi Rajendiran
Summary: This work proposes a rapid and sensitive spectroscopic method for detecting melamine in food products using rare-earth Terbium-doped Graphene Quantum Dots (Tb-GQDs) synthesized by microwave and simple chemical conjugation methods. The synthesized Tb-GQDs show a spherical shape with a size of approximately 6 nm and a quantum yield of 52%. The maximum detection limit for melamine concentration in milk and milk products is found to be 0.31 μM. The dual emitting Tb-GQDs provide a sensitive and effective platform for real-time detection of melamine in food samples, particularly in milk, and show promising potential in the food industry.
MICROCHEMICAL JOURNAL
(2024)
Review
Chemistry, Analytical
Piyush Dey, Mandeep Kaur, Akhil Khajuria, Dilmeet Kaur, Manpreet Singh, Hema Kumari Alajangi, Neha Singla, Gurpal Singh, Ravi Pratap Barnwal
Summary: Environmental issues, such as the uncontrolled release of dangerous pollutants, have significant impacts on human health. Traditional methods for detecting pollutants require specialized personnel and equipment, but nanotechnology has improved the performance of biosensors. This article discusses the use of nanotechnology in pollutant detection and the associated techniques.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Sa Dong, Qiuyun Shi, Lingjun Guan, Yulong Wang, Pengyan Liu, Cunzheng Zhang, Jianguo Feng
Summary: In this study, a highly sensitive indirect competitive chemiluminescence enzyme immunoassay (icCLEIA) method was developed for the determination of sodium pentachlorophenolate (PCP-Na) and its metabolite pentachlorophenol (PCP). The method showed high specificity and affinity with a detection limit of 0.0032 ng/mL for PCP-Na and 0.0192 ng/mL for PCP. The method had no cross reaction with other chlorophenols compounds except for PCP. The average recoveries in chicken, pork and fish samples were 81.3-105.8% with low coefficient of variation (CV).
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Palaniappan Ilayaraja, Murugan Manivannan, Paramasivam Parthiban
Summary: Nirmatrelvir, an antiviral drug used for the treatment of COVID-19, has been recommended by the World Health Organization. We developed an optimized analytical method for the quantification of Nirmatrelvir and its products, with high sensitivity and a wide linear range. The method also meets the requirements for greenness evaluation.
MICROCHEMICAL JOURNAL
(2024)
