Alanine racemase mutants of Mycobacterium tuberculosis require D-alanine for growth and are defective for survival in macrophages and mice

New Classes of Alanine Racemase Inhibitors Identified by High-Throughput Screening Show Antimicrobial Activity against Mycobacterium tuberculosis

(2011) Karen G. Anthony et al.   PLoS One

Depletion of antibiotic targets has widely varying effects on growth

(2011) J.-R. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of theMycobacterium tuberculosisd-Alanine:d-Alanine Ligase, a Target of the Antituberculosis Drug d-Cycloserine

(2010) John B. Bruning et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

New vaccines for tuberculosis

(2010) Stefan HE Kaufmann et al.   LANCET

Tuberculosis drug development: Progress, challenges, and the road ahead

(2010) Ann M. Ginsberg   TUBERCULOSIS

Evaluation of Target Specificity of Antibacterial Agents Using Staphylococcus aureus ddlA Mutants and D-Cycloserine in a Silkworm Infection Model

(2009) K. Kurokawa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Inactivation of the ilvB1 gene in Mycobacterium tuberculosis leads to branched-chain amino acid auxotrophy and attenuation of virulence in mice

(2009) D. Awasthy et al.   MICROBIOLOGY-SGM

Impairment of D-alanine biosynthesis in Mycobacterium smegmatis determines decreased intracellular survival in human macrophages

(2009) O. Chacon et al.   MICROBIOLOGY-SGM

Multidrug-resistant and extensively drug-resistant tuberculosis: a review

(2008) Edward D Chan et al.   CURRENT OPINION IN INFECTIOUS DISEASES