Journal
METHODS
Volume 69, Issue 3, Pages 207-212Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ymeth.2014.08.004
Keywords
R package; Structure/function analysis; Protein sequence; Informational spectrum method
Funding
- National Science Foundation of China [61133010, 61303111, 61373105]
- National Science Foundation for Post-doctoral Scientists of China [2013M541547]
- Anhui University Provincial Natural Science Research Project [KJ2013B328]
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The R package SFAPS has been developed for structure/function analysis of protein sequences based on information spectrum method. The informational spectrum method employs the electron-ion interaction potential parameter as the numerical representation for the protein sequence, and obtains the characteristic frequency of a particular protein interaction after computing the Discrete Fourier Transform for protein sequences. The informational spectrum method is often used to analyze protein sequences, so we developed this software tool, which is implemented as an add-on package to the freely available and widely used statistical language R. Our package is distributed as open source code for Linux, Unix and Microsoft Windows. It is released under the GNU General Public License. (C) 2014 Elsevier Inc. All rights reserved.
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