Inhibition of human amylin fibril formation by insulin-mimetic vanadium complexes

Preface for the Forum on Metals in Medicine and Health: New Opportunities and Approaches to Improving Health

(2013) Debbie C. Crans et al.   INORGANIC CHEMISTRY

Metal Speciation in Health and Medicine Represented by Iron and Vanadium

(2013) Debbie C. Crans et al.   INORGANIC CHEMISTRY

Gold complexes inhibit the aggregation of prion neuropeptides

(2013) Xuesong Wang et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Ruthenium complexes as novel inhibitors of human islet amyloid polypeptide fibril formation

(2013) Lei He et al.   Metallomics

Coordination chemistry may explain pharmacokinetics and clinical response of vanadyl sulfate in type 2 diabetic patients

(2013) Gail R. Willsky et al.   Metallomics

Different Fates of Alzheimer’s Disease Amyloid-β Fibrils Remodeled by Biocompatible Small Molecules

(2012) Jacob A. Irwin et al.   BIOMACROMOLECULES

The potentiality of vanadium in medicinal applications

(2012) Dieter Rehder   Future Medicinal Chemistry

Two-dimensional infrared spectroscopy reveals the complex behaviour of an amyloid fibril inhibitor

(2012) Chris T. Middleton et al.   Nature Chemistry

Stabilization of a vanadium(v)–catechol complex by compartmentalization and reduced solvation inside reverse micelles

(2012) Brant G. Lemons et al.   NEW JOURNAL OF CHEMISTRY

Atomic View of a Toxic Amyloid Small Oligomer

(2012) Arthur Laganowsky et al.   SCIENCE

Absorption, transport and insulin-mimetic properties of bis(maltolato)oxovanadium (IV) in streptozotocin-induced hyperglycemic rats by integrated mass spectrometric techniques

(2011) T. Iglesias-González et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Identification of [PtCl2(phen)] Binding Modes in Amyloid-β Peptide and the Mechanism of Aggregation Inhibition

(2011) Guolin Ma et al.   CHEMISTRY-A EUROPEAN JOURNAL

Anti-diabetic effects of a series of vanadium dipicolinate complexes in rats with streptozotocin-induced diabetes

(2011) Gail R. Willsky et al.   COORDINATION CHEMISTRY REVIEWS

Metal-based anti-diabetic drugs: advances and challenges

(2011) Aviva Levina et al.   DALTON TRANSACTIONS

Palladium Complexes Affect the Aggregation of Human Prion Protein PrP106-126

(2011) Yanli Wang et al.   INORGANIC CHEMISTRY

Antidiabetic vanadium compound and membrane interfaces: interface-facilitated metal complex hydrolysis

(2011) Debbie C. Crans et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

A Two-Site Mechanism for the Inhibition of IAPP Amyloidogenesis by Zinc

(2011) Samer Salamekh et al.   JOURNAL OF MOLECULAR BIOLOGY

2DIR Spectroscopy of Human Amylin Fibrils Reflects Stable β-Sheet Structure

(2011) Lu Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interaction of the Human Prion Protein PrP106-126 with Metal Complexes: Potential Therapeutic Agents Against Prion Disease

(2010) Yanli Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Is Vanadate Reduced by Thiols under Biological Conditions? Changing the Redox Potential of V(V)/V(IV) by Complexation in Aqueous Solution

(2010) Debbie C. Crans et al.   INORGANIC CHEMISTRY

Characterization of interaction and the effect of carbamazepine on the structure of human serum albumin

(2010) Shankara S. Kalanur et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

In SituMisfolding of Human Islet Amyloid Polypeptide at Interfaces Probed by Vibrational Sum Frequency Generation

(2010) Li Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein aggregation diseases: pathogenicity and therapeutic perspectives

(2010) Adriano Aguzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Voltammetric investigation on interaction of protein with chromotrope 2R and its analytical application

(2009) Ni Hui et al.   AMINO ACIDS

Ternary Complexes of Iron, Amyloid-β, and Nitrilotriacetic Acid: Binding Affinities, Redox Properties, and Relevance to Iron-Induced Oxidative Stress in Alzheimer’s Disease

(2009) Dianlu Jiang et al.   BIOCHEMISTRY

Anti-diabetic effects of vanadium(III, IV, V)–chlorodipicolinate complexes in streptozotocin-induced diabetic rats

(2009) Ming Li et al.   BIOMETALS

Inhibiting Islet Amyloid Polypeptide Fibril Formation by the Red Wine Compound Resveratrol

(2009) Rajesh Mishra et al.   CHEMBIOCHEM

Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis

(2009) S. Zraika et al.   DIABETOLOGIA

Association of Highly Compact Type II Diabetes Related Islet Amyloid Polypeptide Intermediate Species at Physiological Temperature Revealed by Diffusion NMR Spectroscopy

(2009) Ronald Soong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Elucidating the Mechanism of Lipid Membrane-Induced IAPP Fibrillogenesis and Its Inhibition by the Red Wine Compound Resveratrol: A Synchrotron X-ray Reflectivity Study

(2009) Florian Evers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular mechanisms for protein-encoded inheritance

(2009) Jed J W Wiltzius et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Vanadium treatment of type 2 diabetes: A view to the future

(2008) Katherine H. Thompson et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Tracking Fiber Formation in Human Islet Amyloid Polypeptide with Automated 2D-IR Spectroscopy

(2008) David B. Strasfeld et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Insights into the Polymorphism of Amyloid-Like Fibrils Formed by Region 20−29 of Amylin Revealed by Solid-State NMR and X-ray Fiber Diffraction

(2008) Jillian Madine et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Platinum-based inhibitors of amyloid-  as therapeutic agents for Alzheimer's disease

(2008) K. J. Barnham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic structure of the cross-β spine of islet amyloid polypeptide (amylin)

(2008) Jed J.W. Wiltzius et al.   PROTEIN SCIENCE

Copper(II) inhibits the formation of amylin amyloid in vitro

(2007) Benjamin Ward et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Low levels of asparagine deamidation can have a dramatic effect on aggregation of amyloidogenic peptides: Implications for the study of amyloid formation

(2002) Melanie R. Nilsson et al.   PROTEIN SCIENCE