Cellular transport and homeostasis of essential and nonessential metals

Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron

(2011) Jorge J. Pinilla-Tenas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hepcidin Treatment Modulates the Expression of Divalent Metal Transporter-1, Ceruloplasmin, and Ferroportin-1 in the Rat Cerebral Cortex and Hippocampus

(2011) Lin Li et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Pathways for the regulation of hepcidin expression in anemia of chronic disease and iron deficiency anemia in vivo

(2011) I. Theurl et al.   HAEMATOLOGICA

Presenilins Promote the Cellular Uptake of Copper and Zinc and Maintain Copper Chaperone of SOD1-dependent Copper/Zinc Superoxide Dismutase Activity

(2011) Mark A. Greenough et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemical properties and in vivo effects of the SOD1 zinc-binding site mutant (H80G)

(2011) Marjatta Son et al.   JOURNAL OF NEUROCHEMISTRY

Mechanisms of methylmercury-induced neurotoxicity: Evidence from experimental studies

(2011) Marcelo Farina et al.   LIFE SCIENCES

High sensitivity of RBL-2H3 cells to cadmium and manganese: an implication of the role of ZIP8

(2011) Hitomi Fujishiro et al.   Metallomics

ATP7A-related copper transport diseases—emerging concepts and future trends

(2011) Stephen G. Kaler   Nature Reviews Neurology

Double-blind, vehicle-controlled randomized twelve-month neurodevelopmental toxicity study of common aluminum salts in the rat

(2011) J. Poirier et al.   NEUROSCIENCE

The Zinc Transporter SLC39A14/ZIP14 Controls G-Protein Coupled Receptor-Mediated Signaling Required for Systemic Growth

(2011) Shintaro Hojyo et al.   PLoS One

Hepcidin Is Involved in Iron Regulation in the Ischemic Brain

(2011) Hui Ding et al.   PLoS One

Does lead use the intestinal absorptive pathways of iron? Impact of iron status on murine 210Pb and 59Fe absorption in duodenum and ileum in vivo

(2011) Bernd Elsenhans et al.   TOXICOLOGY

Contribution of aquaporin 9 and multidrug resistance-associated protein 2 to differential sensitivity to arsenite between primary cultured chorion and amnion cells prepared from human fetal membranes

(2011) Yuta Yoshino et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Copper Metallochaperones

(2010) Nigel J. Robinson et al.   Annual Review of Biochemistry

Hepcidin and Disorders of Iron Metabolism

(2010) Tomas Ganz et al.   Annual Review of Medicine

Molecular evidence and physiological characterization of iron absorption in isolated enterocytes of rainbow trout (Oncorhynchus mykiss): Implications for dietary cadmium and lead absorption

(2010) Raymond W.M. Kwong et al.   AQUATIC TOXICOLOGY

In vitro characterization of cadmium transport along the gastro-intestinal tract of freshwater rainbow trout (Oncorhynchus mykiss)

(2010) Joel S. Klinck et al.   AQUATIC TOXICOLOGY

Effects of dietary cadmium exposure on tissue-specific cadmium accumulation, iron status and expression of iron-handling and stress-inducible genes in rainbow trout: Influence of elevated dietary iron

(2010) Raymond W.M. Kwong et al.   AQUATIC TOXICOLOGY

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Copper handling machinery of the brain

(2010) Svetlana Lutsenko et al.   Metallomics

Affinity gradients drive copper to cellular destinations

(2010) Lucia Banci et al.   NATURE

Biological metals and Alzheimer's disease: Implications for therapeutics and diagnostics

(2010) James A. Duce et al.   PROGRESS IN NEUROBIOLOGY

Effects of Arsenic on Maternal and Fetal Health

(2009) Marie Vahter   Annual Review of Nutrition

Metabolism of arsenic in human liver: the role of membrane transporters

(2009) Zuzana Drobná et al.   ARCHIVES OF TOXICOLOGY

A Ferroportin Transcript that Lacks an Iron-Responsive Element Enables Duodenal and Erythroid Precursor Cells to Evade Translational Repression

(2009) De-Liang Zhang et al.   Cell Metabolism

Manganese-Induced Dopaminergic Neurodegeneration: Insights into Mechanisms and Genetics Shared with Parkinson’s Disease

(2009) Alexandre Benedetto et al.   CHEMICAL REVIEWS

Human copper transporters: mechanism, role in human diseases and therapeutic potential

(2009) Arnab Gupta et al.   Future Medicinal Chemistry

Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation

(2009) Zhaobao Yin et al.   JOURNAL OF NEUROCHEMISTRY

Metalloproteins and metal sensing

(2009) Kevin J. Waldron et al.   NATURE

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

(2009) Aaron D Gitler et al.   NATURE GENETICS

Disruption of Histone Modification and CARM1 Recruitment by Arsenic Represses Transcription at Glucocorticoid Receptor-Regulated Promoters

(2009) Fiona D. Barr et al.   PLoS One

Unexpected expression of  - and  -globin in mesencephalic dopaminergic neurons and glial cells

(2009) M. Biagioli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of aquaporin 9 in cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes

(2009) Yasuhiro Shinkai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Oxidative damage and neurodegeneration in manganese-induced neurotoxicity

(2009) Dejan Milatovic et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Involvement of DMT1 +IRE in the transport of lead in an in vitro BBB model

(2009) Qiang Wang et al.   TOXICOLOGY IN VITRO

Cell-Specific Trafficking Suggests a new role for Renal ATP7B in the Intracellular Copper Storage

(2009) Natalie Barnes et al.   TRAFFIC

Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms

(2008) Detmar Beyersmann et al.   ARCHIVES OF TOXICOLOGY

Ctr2 is partially localized to the plasma membrane and stimulates copper uptake in COS-7 cells

(2008) Jesse Bertinato et al.   BIOCHEMICAL JOURNAL

The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression

(2008) Paul J. Schmidt et al.   Cell Metabolism

Effects of water chemistry variables on gill binding and acute toxicity of cadmium in rainbow trout (Oncorhynchus mykiss): A biotic ligand model (BLM) approach

(2008) Som Niyogi et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Coordination compounds of bis(5-tetrazolyl)amine with manganese(ii), zinc(ii) and cadmium(ii): synthesis, structure and magnetic properties

(2008) Na Liu et al.   DALTON TRANSACTIONS

Huntingtin-interacting Proteins, HIP14 and HIP14L, Mediate Dual Functions, Palmitoyl Acyltransferase and Mg2+Transport

(2008) Angela Goytain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metal ions in biological catalysis: from enzyme databases to general principles

(2008) Claudia Andreini et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Slc39a14 Gene Encodes ZIP14, A Metal/Bicarbonate Symporter: Similarities to the ZIP8 Transporter

(2008) K. Girijashanker et al.   MOLECULAR PHARMACOLOGY

Lead and Cadmium Synergistically Enhance the Expression of Divalent Metal Transporter 1 Protein in Central Nervous System of Developing Rats

(2008) Chengwu Gu et al.   NEUROCHEMICAL RESEARCH

Structure of the membrane proximal oxidoreductase domain of human Steap3, the dominant ferrireductase of the erythroid transferrin cycle

(2008) A. K. Sendamarai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease

(2008) J. Salazar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic, and Chromium

(2007) Konstantin Salnikow et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Multiple pathways of Pb2+ permeation in rat cerebellar granule neurones

(2003) Monica Mazzolini et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of the rat blood-brain barrier choline transporter by manganese chloride

(2003) Paul R. Lockman et al.   JOURNAL OF NEUROCHEMISTRY