Analysis of the DNA damage produced by a platinum–acridine antitumor agent and its effects in NCI-H460 lung cancer cells

Unique platinum–DNA interactions may lead to more effective platinum-based antitumor drugs

(2011) Seiji Komeda   Metallomics

Spectrum of Cellular Responses to Pyriplatin, a Monofunctional Cationic Antineoplastic Platinum(II) Compound, in Human Cancer Cells

(2011) K. S. Lovejoy et al.   MOLECULAR CANCER THERAPEUTICS

Replacement of a Thiourea with an Amidine Group in a Monofunctional Platinum–Acridine Antitumor Agent. Effect on DNA Interactions, DNA Adduct Recognition and Repair

(2011) Hana Kostrhunova et al.   MOLECULAR PHARMACEUTICS

Unusual Reactivity of a Potent Platinum–Acridine Hybrid Antitumor Agent

(2011) Leigh A. Graham et al.   ACS Medicinal Chemistry Letters

Inhibition of DNA Synthesis by a Platinum–Acridine Hybrid Agent Leads to Potent Cell Kill in Nonsmall Cell Lung Cancer

(2011) Christopher L. Smyre et al.   ACS Medicinal Chemistry Letters

Determination of Pt–DNA adducts and the sub-cellular distribution of Pt in human cancer cell lines and the leukocytes of cancer patients, following mono- or combination treatments, by inductively-coupled plasma mass spectrometry

(2010) Aref Zayed et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Rates of intercalator-driven platination of DNA determined by a restriction enzyme cleavage inhibition assay

(2010) Jayati Roy Choudhury et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Analytical methodologies for metallomics studies of antitumor Pt-containing drugs

(2009) Diego Esteban-Fernández et al.   Metallomics

A Non-Cross-Linking Platinum−Acridine Agent with Potent Activity in Non-Small-Cell Lung Cancer

(2008) Zhidong Ma et al.   JOURNAL OF MEDICINAL CHEMISTRY

cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects

(2008) Katherine S. Lovejoy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA