Targeting selenium metabolism and selenoproteins: Novel avenues for drug discovery

Focus on mammalian thioredoxin reductases — Important selenoproteins with versatile functions

(2009) Elias S.J. Arnér   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The human selenoproteome: recent insights into functions and regulation

(2009) M. A. Reeves et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Selenium and Vitamin E Supplementation for Cancer Prevention

(2009) Margaret P. Rayman   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Inhibition of Selenium Metabolism in the Oral Pathogen Treponema denticola

(2009) S. Jackson-Rosario et al.   JOURNAL OF BACTERIOLOGY

Auranofin disrupts selenium metabolism in Clostridium difficile by forming a stable Au–Se adduct

(2009) Sarah Jackson-Rosario et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Arsenic trioxide and auranofin inhibit selenoprotein synthesis: implications for chemotherapy for acute promyelocytic leukaemia

(2008) S Talbot et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of thioredoxin reductase by mansonone F analogues: Implications for anticancer activity

(2008) Zhong Liu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Selenium Compounds and Selenoproteins in Cancer

(2008) Regina Brigelius-Flohé   CHEMISTRY & BIODIVERSITY

Selenium and anticarcinogenesis: underlying mechanisms

(2008) Matthew I Jackson et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers

(2008) Scott M. Lippman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Platyhelminth Mitochondrial and Cytosolic Redox Homeostasis Is Controlled by a Single Thioredoxin Glutathione Reductase and Dependent on Selenium and Glutathione

(2008) Mariana Bonilla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selenoproteins

(2008) Jun Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thioredoxin system inhibitors as mediators of apoptosis for cancer therapy

(2008) Kathryn F. Tonissen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Identification of oxadiazoles as new drug leads for the control of schistosomiasis

(2008) Ahmed A Sayed et al.   NATURE MEDICINE

Cell Death by SecTRAPs: Thioredoxin Reductase as a Prooxidant Killer of Cells

(2008) Karin Anestål et al.   PLoS One

The essential toxin: The changing perception of selenium in environmental sciences

(2008) Markus Lenz et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Will new antischistosomal drugs finally emerge?

(2008) Donato Cioli et al.   TRENDS IN PARASITOLOGY

Quantitative High-Throughput Screen Identifies Inhibitors of the Schistosoma mansoni Redox Cascade

(2008) Anton Simeonov et al.   PLoS Neglected Tropical Diseases

Anti-cancer potential of gold complexes

(2008) E. R. T. Tiekink   INFLAMMOPHARMACOLOGY

Selenium as an anticancer nutrient: roles in cell proliferation and tumor cell invasion

(2007) Huawei Zeng et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY