Comparative analysis of plasma metabolomics response to metabolic challenge tests in healthy subjects and influence of the FTO obesity risk allele

Metabolite Profiles During Oral Glucose Challenge

(2013) Jennifer E. Ho et al.   DIABETES

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

(2013) Tove Fall et al.   PLOS MEDICINE

Glucose-dependent insulinotropic polypeptide induces cytokine expression, lipolysis, and insulin resistance in human adipocytes

(2012) Katharina Timper et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

KmL3D: A non-parametric algorithm for clustering joint trajectories

(2012) C. Genolini et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Metabolic Signatures of Insulin Resistance in 7,098 Young Adults

(2012) P. Wurtz et al.   DIABETES

Direct effect of GLP-1 infusion on endogenous glucose production in humans

(2012) M. Seghieri et al.   DIABETOLOGIA

The dynamic range of the human metabolome revealed by challenges

(2012) Susanne Krug et al.   FASEB JOURNAL

Bayesian Independent Component Analysis Recovers Pathway Signatures from Blood Metabolomics Data

(2012) Jan Krumsiek et al.   JOURNAL OF PROTEOME RESEARCH

GLP-1 Receptor Agonist and Non-Alcoholic Fatty Liver Disease

(2012) Jinmi Lee et al.   Diabetes & Metabolism Journal

Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data

(2011) Jan Krumsiek et al.   BMC Systems Biology

Study of the Potential Association of Adipose Tissue GLP-1 Receptor with Obesity and Insulin Resistance

(2011) Joan Vendrell et al.   ENDOCRINOLOGY

Glucagon-like peptide-1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signalling alteration induced by a high-fat diet in nonalcoholic steatohepatitis

(2011) Gianluca Svegliati-Baroni et al.   LIVER INTERNATIONAL

Postprandial changes in plasma acylcarnitine concentrations as markers of fatty acid flux in overweight and obesity

(2011) Maria A. Ramos-Roman et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status

(2011) Linette Pellis et al.   Metabolomics

Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics

(2011) Werner Römisch-Margl et al.   Metabolomics

Human metabolic individuality in biomedical and pharmaceutical research

(2011) Karsten Suhre et al.   NATURE

The obesity-associated Fto gene is a transcriptional coactivator

(2010) Qiong Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels

(2010) Tea Berulava et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genes and lifestyle factors in obesity: results from 12 462 subjects from MONICA/KORA

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New metabolic interdependencies revealed by plasma metabolite profiling after two dietary challenges

(2010) Thomas Skurk et al.   Metabolomics

Reversal of Obesity and Insulin Resistance by a Non-Peptidic Glucagon-Like Peptide-1 Receptor Agonist in Diet-Induced Obese Mice

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Interpreting Metabolomic Profiles using Unbiased Pathway Models

(2010) Rahul C. Deo et al.   PLoS Computational Biology

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

KmL: k-means for longitudinal data

(2009) Christophe Genolini et al.   COMPUTATIONAL STATISTICS

Incidence of Type 2 diabetes in the elderly German population and the effect of clinical and lifestyle risk factors: KORA S4/F4 cohort study

(2009) W. Rathmann et al.   DIABETIC MEDICINE

Challenging homeostasis to define biomarkers for nutrition related health

(2009) Ben van Ommen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A genome-wide perspective of genetic variation in human metabolism

(2009) Thomas Illig et al.   NATURE GENETICS

Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations

(2009) Melanie Kolz et al.   PLoS Genetics

Changes of the plasma metabolome during an oral glucose tolerance test: is there more than glucose to look at?

(2008) Xinjie Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Common Variation in the FTO Gene Alters Diabetes-Related Metabolic Traits to the Extent Expected Given Its Effect on BMI

(2008) R. M. Freathy et al.   DIABETES

Gene–Environment Interactions and Susceptibility to Metabolic Syndrome and Other Chronic Diseases

(2008) Jose M. Ordovas et al.   JOURNAL OF PERIODONTOLOGY

Assessing individual metabolic responsiveness to a lipid challenge using a targeted metabolomic approach

(2008) Angela M. Zivkovic et al.   Metabolomics

Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity

(2008) Oded Shaham et al.   Molecular Systems Biology

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

(2008) Gudmar Thorleifsson et al.   NATURE GENETICS

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

(2008) Cristen J Willer et al.   NATURE GENETICS

Epidemiological Study Designs to Investigate Gene–Behavior Interactions in the Context of Human Obesity

(2008) Nicholas J. Wareham et al.   Obesity

Gene–Environment Interactions in the Etiology of Obesity: Defining the Fundamentals

(2008) Claude Bouchard   Obesity

Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum

(2008) Christian Gieger et al.   PLoS Genetics

Serum concentration of small dense low-density lipoprotein-cholesterol during oral glucose tolerance test and oral fat tolerance test

(2007) Kyoko Ogita et al.   CLINICA CHIMICA ACTA

The entero-insular axis: implications for human metabolism

(2007) Lakshminarayan R. Ranganath   CLINICAL CHEMISTRY AND LABORATORY MEDICINE