Article
Oncology
Baek Gyu Jun, Moonho Kim, Hwang Sik Shin, Jee-Jeon Yi, Sang-Wook Yi
Summary: The study indicates that overweight and obesity significantly increase the risk of hepatocellular carcinoma in Korean adults, especially in those with a BMI over 25. Additionally, ALT levels can reduce the risk of HCC caused by obesity to some extent, but may not accurately predict the progression to HCC in women and older adults.
BRITISH JOURNAL OF CANCER
(2022)
Article
Endocrinology & Metabolism
Ayaka Kobayashi, Hiroshi Okada, Masahide Hamaguchi, Kazushiro Kurogi, Hiroaki Murata, Masato Ito, Michiaki Fukui
Summary: This study found that the stable, metabolically healthy nonobesity group had a lower risk of incident type 2 diabetes compared to the stable, metabolically healthy obesity group. When metabolically healthy obese individuals changed to metabolically healthy nonobese status, their risk of developing type 2 diabetes was similar to that of participants in the stable metabolically healthy nonobesity group. These findings suggest the importance of paying attention to changes in metabolic phenotypes to prevent incident type 2 diabetes in the Japanese population.
Article
Multidisciplinary Sciences
Peng Gu, Bin Pu, Qiao Xin, Dan Yue, LieLiang Luo, JiaSheng Tao, HaiShan Li, Ming Chen, MingHua Hu, XiaoRong Hu, XiaoHui Zheng, ZhanPeng Zeng
Summary: This study aimed to explore the correlation between insulin resistance and bone mineral density (BMD), and osteoporosis (OP) in postmenopausal patients with type 2 diabetes mellitus (T2DM). It found that METS-IR was positively correlated with BMD and a protective factor for OP in a specific range.
SCIENTIFIC REPORTS
(2023)
Article
Health Care Sciences & Services
Anastasiia S. Boiko, Irina A. Mednova, Elena G. Kornetova, Anastasiia A. Goncharova, Arkadiy Semke, Nikolay A. Bokhan, Svetlana A. Ivanova
Summary: Metabolic syndrome (MetS) is a common complication of schizophrenia that is exacerbated by long-term use of antipsychotics. The study found that levels of leptin were significantly increased in MetS patients, while ghrelin levels were significantly decreased. There were fewer significant correlations between ghrelin and other hormones in MetS patients compared to those without MetS.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Multidisciplinary Sciences
Leandro Cordero, Michael R. Stenger, Mark B. Landon, Craig A. Nankervis
Summary: Excessive gestational weight gain is associated with low exclusive breastfeeding and any breastfeeding rates, as well as with diabetes and obesity in women. However, excessive gestational weight gain is not an independent predictor of low exclusive breastfeeding or any breastfeeding at discharge.
Article
Cardiac & Cardiovascular Systems
Emanuela Orsi, Anna Solini, Giuseppe Penno, Enzo Bonora, Cecilia Fondelli, Roberto Trevisan, Monica Vedovato, Franco Cavalot, Olga Lamacchia, Jonida Haxhi, Antonio Nicolucci, Giuseppe Pugliese
Summary: This study investigated the relationship between BMI and central adiposity surrogate measures with all-cause mortality in individuals with type 2 diabetes. The results showed that mildly and moderately obese individuals had a lower risk of mortality compared to normal-weight individuals, while severely obese individuals had a higher risk. The relationship between BMI and mortality did not change after adjusting for smoking, physical activity, and comorbidities. Additionally, central adiposity measures such as waist circumference, waist-to-height ratio, and A Body Shape Index were found to be associated with mortality risk.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Endocrinology & Metabolism
William H. H. Dietz
Summary: This study compared the prevalence of pediatric obesity during the COVID-19 lockdown with the annual increases in obesity in NHANES. The changes in prevalence observed in two surveys during the lockdown were 28 to 63 times greater than the annual changes in obesity in NHANES. Increases in obesity were greater in Black and Hispanic youth than in White youth. The COVID-19 lockdown exacerbated the disparities in obesity among this age group.
Article
Endocrinology & Metabolism
Ming Ying, Xiangming Hu, Qiang Li, Haojian Dong, Yingling Zhou, Zhujun Chen
Summary: This study examined the relationship between BMI trajectories and MetS, revealing that long-term BMI measurements are associated with cumulative incident MetS. Different BMI trajectories have varying impacts on the risk of MetS, providing important guidance for the prevention and management of MetS.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Orthopedics
A. Batushansky, S. Zhu, R. K. Komaravolu, S. South, P. Mehta-D'souza, T. M. Griffin
Summary: This article provides another perspective by discussing how obesity increases the risk of knee osteoarthritis by altering metabolism and inflammation. The relationship between metabolic syndrome and osteoarthritis is context-dependent, and the factors contributing to obesity-induced osteoarthritis may differ between men and women. Metabolomic analyses have identified potential diagnostic and prognostic biomarkers for knee osteoarthritis.
OSTEOARTHRITIS AND CARTILAGE
(2022)
Article
Gastroenterology & Hepatology
Min Kyu Kang, Yu Rim Lee, Se Young Jang, Won Young Tak, Young Oh Kweon, Jeong Eun Song, Rohit Loomba, Soo Young Park, Jung Gil Park
Summary: The study aims to evaluate the association of cardiovascular risk in two terminologies (NAFLD and MAFLD) and subgroups of MAFLD. The results showed that both NAFLD and MAFLD were significantly associated with coronary artery calcification (CAC), but only MAFLD remained associated with CAC after adjusting for sex and age. Diabetic MAFLD predicted high-risk CVD phenotypes the best, while metabolic risk abnormalities in nondiabetic MAFLD patients were also independently associated with the risk of CVD.
HEPATOLOGY INTERNATIONAL
(2023)
Article
Nutrition & Dietetics
Carla Cristine Nascimento da Silva Coelho, Maylla Luanna Barbosa Martins Braganca, Bianca Rodrigues de Oliveira, Heloisa Bettiol, Marco Antonio Barbieri, Viviane Cunha Cardoso, Antonio Augusto Moura da Silva
Summary: This study found that individuals with normal weight obesity (NWO) have a risk ratio for metabolic syndrome similar to individuals with overweight/obesity (OWO), highlighting the need to assess body fat percentages, even in BMI-designated normal weight individuals.
Article
Endocrinology & Metabolism
Josephine Haas, Mikael Andersson Franko, Anna Lindholm Olinder, Thomas Nystrom, Martina Persson
Summary: This study examines the time-trends in BMI distributions of young females with and without type 1 diabetes and finds that females with T1D have increasing BMI overtime and are heavier than females without T1D. The study also shows that overweight and obesity are independent risk factors for diabetes angiopathy.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2023)
Article
Cardiac & Cardiovascular Systems
Chung-Ming Tu, Ting-En Wei, Guo-Shiang Tseng, Chien-Chou Chen, Cheng-Wei Liu
Summary: The study revealed a significant association between elevated serum uric acid levels, body shape index, and body roundness index with incident metabolic syndrome. Elevated uric acid levels had a dose-response effect on MetS independent of BMI, BRI, and BSI in healthy individuals. Future studies can consider using uric acid levels to stratify cardiometabolic risk in healthy individuals.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Article
Genetics & Heredity
Jiarui Mi, Zhengye Liu
Summary: Previous studies have shown that obesity and type 2 diabetes are associated with an increased risk of carpal tunnel syndrome, with these risk factors being independent of each other.
FRONTIERS IN GENETICS
(2021)
Article
Medicine, General & Internal
Natalia Drobek, Pawel Sowa, Piotr Jankowski, Maciej Haberka, Zbigniew Gasior, Dariusz Kosior, Danuta Czarnecka, Andrzej Pajak, Karolina Szostak-Janiak, Agnieszka Krzykwa, Malgorzata Setny, Pawel Koziel, Marlena Paniczko, Jacek Jamiolkowski, Irina Kowalska, Karol Kaminski
Summary: This study aimed to evaluate the prevalence of undiagnosed diabetes and prediabetes in patients with chronic coronary syndromes (CCS) and identify factors associated with dysglycemia. Results showed a 5.1% newly diagnosed diabetes rate and 72.3% prediabetes rate among study participants. Body mass index and high-density lipoprotein cholesterol were identified as important factors in assessing the risk of dysglycemia development after hospital discharge.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Chan-Hee Jung, Sang-Hee Jung, Bo-Yeon Kim, Chul-Hee Kim, Sung-Koo Kang, Ji-Oh Mok
CARDIOVASCULAR DIABETOLOGY
(2015)
Article
Endocrinology & Metabolism
Chan-Hee Jung, Sang-Hee Jung, Kyu-Jin Kim, Bo-Yeon Kim, Chul-Hee Kim, Sung-Koo Kang, Ji-Oh Mok
DIABETES & VASCULAR DISEASE RESEARCH
(2015)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jisang Park, Hyun Sook Hong, Chul-Hee Kim, Eun Hye Lee, Sun Hye Jeong, A. Leum Lee, Heon Lee
AMERICAN JOURNAL OF ROENTGENOLOGY
(2016)
Article
Endocrinology & Metabolism
Chul-Hee Kim, Hong-Kyu Kim, Eun-Hee Kim, Sung-Jin Bae, Jaewon Choe, Joong-Yeol Park
DIABETES RESEARCH AND CLINICAL PRACTICE
(2016)
Article
Endocrinology & Metabolism
Hye Jeong Kim, Ji-Oh Mok, Chul Hee Kim, Yeo Joo Kim, Sang Jin Kim, Hyeong Kyu Park, Dong Won Byun, Kyoil Suh, Myung Hi Yoo
ENDOCRINE RESEARCH
(2017)
Article
Nutrition & Dietetics
Chan-Hee Jung, Kyu-Jin Kim, Bo-Yeon Kim, Chul-Hee Kim, Sung Koo Kang, Ji-Oh Mok
NUTRITION RESEARCH
(2016)
Article
Endocrinology & Metabolism
Chan-Hee Jung, Sang-Hee Jung, Bo-Yeon Kim, Chul-Hee Kim, Sung-Koo Kang, Ji-Oh Mok
JOURNAL OF DIABETES AND ITS COMPLICATIONS
(2017)
Article
Endocrinology & Metabolism
Chul-Hee Kim, Hong-Kyu Kim, Eun-Hee Kim, Sung-Jin Bae, Young-Ju Jung, Jaewon Choi, Joong-Yeol Park
ACTA DIABETOLOGICA
(2015)
Article
Geriatrics & Gerontology
Tae-Eun Kim, Dong Hyun Lee, Yoon-Jeong Kim, Ji Oh Mok, Chul-Hee Kim, Jeong-Ho Park, Tae-Kyeong Lee, Kwangsun Yoo, Yong Jeong, Yunhwan Lee, Sun Ah Park
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
(2015)
Article
Endocrinology & Metabolism
Chul-Hee Kim, Hong-Kyu Kim, Bo-Yeon Kim, Chan-Hee Jung, Ji-Oh Mok, Sung-Koo Kang
JOURNAL OF DIABETES INVESTIGATION
(2015)
Review
Endocrinology & Metabolism
Hong-Kyu Kim, Chul-Hee Kim
Summary: Age-related changes in skeletal muscles are closely associated with decreases in muscle strength and functional decline, but their associations with cardiometabolic diseases are inconsistent. Muscle quality, especially myosteatosis, plays a crucial role in cardiometabolic health, yet it is less explored compared with muscle mass. The standard definition of myosteatosis and its impact on metabolic and cardiovascular health remain largely unknown, and further research is needed to establish myosteatosis as a therapeutic target for cardiometabolic diseases.
ENDOCRINOLOGY AND METABOLISM
(2021)
Article
Endocrinology & Metabolism
Dug-Hyun Choi, Chan-Hee Jung, Ji-Oh Mok, Chul-Hee Kim, Sung-Koo Kang, Bo-Yeon Kim
ENDOCRINOLOGY AND METABOLISM
(2018)
Article
Endocrinology & Metabolism
Chan-Hee Jung, Bora Lee, Dug-Hyun Choi, Sang-Hee Jung, Bo-Yeon Kim, Chul-Hee Kim, Sung-Koo Kang, Ji-Oh Mok
DIABETES RESEARCH AND CLINICAL PRACTICE
(2017)
Article
Endocrinology & Metabolism
Bo-Yeon Kim, Ji-Oh Mok, Sung-Koo Kang, Sun-Young Jang, Chan-Hee Jung, Chul-Hee Kim
Article
Endocrinology & Metabolism
Kyu-Jin Kim, Bo-Yeon Kim, Ji-Oh Mok, Chul-Hee Kim, Sung-Koo Kang, Chan-Hee Jung
ENDOCRINOLOGY AND METABOLISM
(2015)