Thrombin mutant W215A/E217A treatment improves neurological outcome and attenuates central nervous system damage in experimental autoimmune encephalomyelitis

Neurotoxicity of the anticoagulant-selective E149A-activated protein C variant after focal ischemic stroke in mice

(2013) Yaoming Wang et al.   BLOOD CELLS MOLECULES AND DISEASES

Activated Protein C Analog Protects From Ischemic Stroke and Extends the Therapeutic Window of Tissue-Type Plasminogen Activator in Aged Female Mice and Hypertensive Rats

(2013) Yaoming Wang et al.   STROKE

Gilt required for RTL550-CYS-MOG to treat experimental autoimmune encephalomyelitis

(2012) Gregory G. Burrows et al.   METABOLIC BRAIN DISEASE

Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation

(2012) Dimitrios Davalos et al.   Nature Communications

The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A

(2011) M. J. Flick et al.   BLOOD

Role of dihydrotestosterone in post-stroke peripheral immunosuppression after cerebral ischemia

(2011) Suzan Dziennis et al.   BRAIN BEHAVIOR AND IMMUNITY

Thrombin Mutant W215A/E217A Treatment Improves Neurological Outcome and Reduces Cerebral Infarct Size in a Mouse Model of Ischemic Stroke

(2011) Michelle A. Berny-Lang et al.   STROKE

Thrombomodulin is required for the antithrombotic activity of thrombin mutant W215A/E217A in a mouse model of arterial thrombosis

(2011) Cristina P. Vicente et al.   THROMBOSIS RESEARCH

Fibrinogen Depleting Agent Batroxobin has a Beneficial Effect on Experimental Autoimmune Encephalomyelitis

(2010) Yang Yang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

A small-molecule inhibitor of macrophage migration inhibitory factor for the treatment of inflammatory disease

(2010) Aaron P. Kithcart et al.   FASEB JOURNAL

Membrane Estrogen Receptor Regulates Experimental Autoimmune Encephalomyelitis through Up-regulation of Programmed Death 1

(2009) C. Wang et al.   JOURNAL OF IMMUNOLOGY

Recombinant TCR Ligand Reverses Clinical Signs and CNS Damage of EAE Induced by Recombinant Human MOG

(2009) Sushmita Sinha et al.   Journal of Neuroimmune Pharmacology

Activated protein C prevents glutamate- and thrombin-induced activation of nuclear factor-κB in cultured hippocampal neurons

(2009) L. Gorbacheva et al.   NEUROSCIENCE

Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets

(2008) May H. Han et al.   NATURE