4.2 Article

Synthesis of pyrido[1,2-a]benzimidazoles by electroreductive heterocyclization of 1-(2-nitroaryl)pyridinium chlorides

Journal

MENDELEEV COMMUNICATIONS
Volume 22, Issue 6, Pages 312-313

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ELSEVIER
DOI: 10.1016/j.mencom.2012.11.011

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Funding

  1. state task for Yaroslavl State University [3.4523.2011]
  2. Presidium of the Russian Academy of Sciences

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The electrochemical reduction of N-(2-nitro-4-R-phenyl)pyridinium chlorides (R = CF3, CN, CO2Et) at a lead cathode in HCl/(PrOH)-O-i/H2O affords the corresponding 7-R-pyrido[1,2-a]benzimidazoles in 70-94% yields.

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