Editorial Material
Oncology
Vissy M. Elad, Trevena Anton, Natalie C. Ganios, Vito W. Rebecca
Summary: Acral lentiginous melanoma (ALM) is a subtype of cutaneous melanoma with poor outcomes, especially among individuals with skin of color. Racial disparities in ALM are influenced by a lack of representative educational materials, leading to a lack of knowledge about disease risk, incidence patterns, and disease presentation in patients with skin of color. The atypical presentation of ALM on acral volar skin sites makes early detection challenging, emphasizing the importance of adequate educational materials.
PIGMENT CELL & MELANOMA RESEARCH
(2023)
Article
Medicine, General & Internal
Astrid Herzum, Corrado Occella, Lodovica Gariazzo, Carlotta Pastorino, Gianmaria Viglizzo
Summary: Corticophobia, the fear of using topical corticosteroids, is becoming a more prevalent issue in industrialized countries, despite the proven safety of these medications for treating atopic dermatitis. This study found that factors such as milder or moderate disease severity, older age of patients, earlier disease onset, and previous healthcare professional consultations were associated with parental corticophobia. Additionally, severe parental corticophobia was significantly associated with a higher level of parental education and a greater impact on parental quality of life. Assessing the risk factors for corticophobia is crucial for developing educational programs that address the concerns of high-risk parents, in order to alleviate unfounded fears and improve treatment adherence.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Dermatology
M. C. B. Hughes, M. Malt, K. Khosrotehrani, B. M. Smithers, A. C. Green
Summary: The study found a significant association between the quality of patients' diets before diagnosis and melanoma thickness, with patients with higher diet quality being less likely to be diagnosed with thick melanoma.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2022)
Article
Oncology
Francois Lagace, Bibi Nuzha Noorah, Santina Conte, Lorena Alexandra Mija, Jasmine Chang, Leila Cattelan, Jonathan LeBeau, Joel Claveau, Irina Turchin, Wayne Gulliver, Robert Gniadecki, Elena Netchiporouk, Wilson H. Miller, Thomas G. Salopek, Elham Rahme, Sandra Pelaez, Ivan V. Litvinov
Summary: This study compared the differences in sun exposure, sun protection, and level of worry for cutaneous melanoma between high-incidence and low-incidence provinces in Atlantic Canada, as well as between different demographic groups. The findings identified significant differences across multiple variables, which will help guide future public health efforts in preventing and reducing the incidence of cutaneous melanoma in the communities.
Article
Computer Science, Information Systems
Joanna Abraham, William L. Galanter, Daniel Touchette, Yinglin Xia, Katherine J. Holzer, Vania Leung, Thomas Kannampallil
Summary: By utilizing a computerized order entry system-integrated function named void, the study aimed to identify the nature and characteristics of medication ordering errors, investigate associated risk factors, and explore strategies to mitigate these risks. Results showed that medication ordering errors were multifactorial and mostly did not result in harm to patients.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2021)
Review
Oncology
Anna Lorenz, Mateusz Kozlowski, Sebastian Lenkiewicz, Sebastian Kwiatkowski, Aneta Cymbaluk-Ploska
Summary: Melanoma of the vulva and vagina is a rare neoplasm with a poor prognosis. Immunotherapy, a rapidly developing cancer treatment method, has limited effectiveness for this rare type of melanoma.
Article
Oncology
Yuval Arbel, Yifat Arbel, Amichai Kerner, Miryam Kerner
Summary: The objectives of this study are to estimate the relationship between obesity (BMI >= 30) and the prevalence of melanoma in different US states, and to examine the possibility of defining a new risk group. The results show a negative correlation between obesity and the incidence of melanoma, especially in the high-risk Caucasian subgroup. It is concluded that primary prevention and secondary prevention measures should be continued, including raising awareness of photoprotection and promoting skin screening among the entire population group, with a focus on the high-risk Caucasian subgroup with BMI < 30.
Article
Education & Educational Research
Johanna Havia, Sonja Lutovac, Tiina Komulainen, Raimo Kaasila
Summary: Interest in a subject is a central factor in preservice teachers' decision to become subject teachers and can impact their teaching and students' interest. However, the interest in minor subjects has been overlooked. This study examined three preservice teachers' narratives and found a weaker interest in minor subjects compared to major subjects.
INTERNATIONAL JOURNAL OF SCIENCE AND MATHEMATICS EDUCATION
(2023)
Review
Dentistry, Oral Surgery & Medicine
Leandro Chambrone, Giovanni Zucchelli
Summary: This article discusses the reasons for the lack of reporting errors and complications in periodontal and implant therapy, and highlights the importance of these reports in selecting the best treatment options and the overall decision-making process.
PERIODONTOLOGY 2000
(2022)
Article
Microbiology
Aaron C. Miller, Alan T. Arakkal, Scott H. Koeneman, Joseph E. Cavanaugh, George R. Thompson, John W. Baddley, Philip M. Polgreen
Summary: The study analyzed diagnostic delays associated with histoplasmosis using IBM Marketscan data, revealing that patients experienced multiple visits and missed opportunities for diagnosis before being diagnosed. The average delay in diagnosis was 39.5 days, with patients who had prior antibiotic use, history of other pulmonary diseases, and visited on weekends being more likely to experience delays. New diagnostic approaches for histoplasmosis are needed.
Article
Dermatology
Mitchell S. Stark, Richard A. Sturm, Yan Pan, Darren J. Smit, Varsha Kommajosyula, Katie J. Lee, Kasturee Jagirdar, Catriona McLean, David L. Duffy, H. Peter Soyer, Victoria J. Mar
Summary: This study performed a rare-variant allele analysis, identifying some genes associated with nodular melanoma (NM), including PTCH1, ARID2, and GHR. Rare variants in the SMO gene, which interacts with PTCH1, were also found, suggesting a potential contribution of the Hedgehog pathway to NM risk.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Review
Oncology
Ioana-Claudia Costin, Loredana G. Marcu
Summary: This study aims to discuss setup errors in breast cancer radiotherapy and evaluate the impact of various factors on these errors.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Rony Shreberk-Hassidim, Stephen M. Ostrowski, David E. Fisher
Summary: One approach to combat malignant melanoma is through early detection by screening melanocytic nevi clinically and dermoscopically. However, the relationship between nevi, which are benign melanocytic proliferations, and melanoma remains unclear. While most melanomas are believed to develop de novo, an increased number of nevi is a strong risk factor for developing melanoma. Various factors, such as pigmentation, genetics, and sun exposure, influence nevus formation and progression to melanoma. This review discusses the clinical, histological, molecular, and genetic factors involved in nevus formation and evolution into melanoma.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Oncology
Alexej Ballhausen, Elizabeth Urias, Stephen K. Gruschkus, Michelle Williams, Maura S. Glover, Yong Qin, Dan S. Gombos, Sapna P. Patel
Summary: The study found that in uveal melanoma Class 1A patients, those with stage III disease and/or large COMS size are at elevated risk for metastasis. Combined clinical decision-making using AJCC stage and COMS size can have a significant impact on improving risk stratification and adapting follow-up intervals for Class 1A UM patients.
Article
Clinical Neurology
Shusaku Omoto, Hidetomo Murakami, Tomotaka Shiraishi, Keiko Bono, Tadashi Umehara, Yasuyuki Iguchi
Summary: Minor hallucinations (MHs) are common in Parkinson's disease (PD), and patients with MHs can have different clinical characteristics depending on when the hallucinations appear. Understanding these differences is important for clinical diagnosis and treatment.
ACTA NEUROLOGICA SCANDINAVICA
(2021)
Article
Pediatrics
Olaf Gefeller, Sonja Mathes, Wolfgang Uter, Annette B. Pfahlberg
Summary: A survey conducted among directors of 436 kindergartens in southern Germany revealed low awareness and understanding of the Global Solar UV index (UVI) as well as low usage of UVI information for sun protection measures. The majority of directors had heard of UVI but only a small number of them used UVI information to adapt sun protective measures. Detailed knowledge about UVI was rare among the respondents and their self-perceived knowledge was significantly higher than their actual knowledge. There was no clear relationship between UVI awareness, knowledge, and use and directors' age, gender, awareness of risk factors for skin cancer, and attitudes towards tanned skin. Future public health campaigns should focus on increasing awareness and understanding of UVI and its importance for sun protection of children.
Editorial Material
Pediatrics
Olaf Gefeller, Katharina Diehl
Article
Pediatrics
Katharina Diehl, Karla S. Lindwedel, Sonja Mathes, Tatiana Goerig, Olaf Gefeller
Summary: Research on tanning bed legislation for minors in North America, Australia, and Europe revealed that Australia has a total ban on minors, about half of European countries have strict bans, while some states in the United States have varying degrees of restrictions on minors.
Article
Virology
Sebastian Einhauser, David Peterhoff, Stephanie Beileke, Felix Guenther, Hans-Helmut Niller, Philipp Steininger, Antje Knoell, Klaus Korn, Melanie Berr, Anja Schuetz, Simon Wiegrebe, Klaus J. Stark, Andre Gessner, Ralph Burkhardt, Michael Kabesch, Holger Schedl, Helmut Kuechenhoff, Annette B. Pfahlberg, Iris M. Heid, Olaf Gefeller, Klaus Ueberla, Ralf Wagner
Summary: In this study, the results of a prospective population-based longitudinal follow-up of SARS-CoV-2 serosurveillance in Tirschenreuth, Germany, were presented. The findings showed an increase in seropositivity from FU1 to FU2, a decrease in the surveillance detection ratio, and a successful vaccination campaign in the elderly population.
Article
Environmental Sciences
Katharina Diehl, Karlijn Thoonen, Eckhard W. Breitbart, Annette B. Pfahlberg, Tatiana Goerig
Summary: This study found that caregivers play a significant role in the sun protection behaviors of children. There were no significant differences in sun protection behaviors between caregivers and non-caregivers, indicating that both groups had deficient sun protection behaviors. However, caregivers who considered themselves role models were more likely to use sun protection measures, and their behaviors were positively associated with children's behaviors.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Oncology
Isabelle Kaiser, Sonja Mathes, Annette B. Pfahlberg, Wolfgang Uter, Carola Berking, Markus Heppt, Theresa Steeb, Katharina Diehl, Olaf Gefeller
Summary: This study assessed the validity of published prediction models for incident cutaneous melanoma. The majority of the studies had high risk of bias and lacked validation of the prediction models. However, there was a reduction in the number of studies with high risk of bias over time.
Article
Allergy
Martin S. Havmose, Wolfgang Uter, Olaf Gefeller, Jeanne D. Johansen
Summary: By conducting a questionnaire and data analysis on hairdressers, exposure patterns related to occupational hand eczema (OHE) were identified, and it was found that poor compliance with wearing protective gloves was the main reason for increased risk of OHE.
CONTACT DERMATITIS
(2023)
Article
Medicine, General & Internal
Isabelle Kaiser, Annette B. Pfahlberg, Sonja Mathes, Wolfgang Uter, Katharina Diehl, Theresa Steeb, Markus V. Heppt, Olaf Gefeller
Summary: Assessing the risk of bias (ROB) is crucial in systematic reviews and meta-analyses in clinical medicine. This study evaluated the inter-rater reliability (IRR) of the Prediction Model Risk of Bias Assessment Tool (PROBAST) and the effects of specialized training. The results showed significant improvement in IRR after receiving customized training and guidance, highlighting the importance of intensive training and context-specific decision rules for correctly applying PROBAST.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Sonja Mathes, Karla S. Lindwedel, Lill Tove Nilsen, Isabelle Kaiser, Annette B. Pfahlberg, Olaf Gefeller
Summary: Epidemiologic studies have shown that tanning beds, which emit ultraviolet radiation, can cause skin cancer. This study analyzed the regulations on commercial indoor tanning, including advertising and information requirements, in multiple countries. The results highlight the need for international collaboration to harmonize the regulations and better protect the public from the risks of tanning beds. Evaluation: 8/10
Article
Health Care Sciences & Services
Isabelle Kaiser, Katharina Diehl, Markus V. Heppt, Sonja Mathes, Annette B. Pfahlberg, Theresa Steeb, Wolfgang Uter, Olaf Gefeller
Summary: Transparent and accurate reporting is crucial for evaluating the validity and applicability of risk prediction models. This study assessed the reporting quality of studies on melanoma risk prediction models and found room for improvement.
