Recent attempts at RNAi-mediated P-glycoprotein downregulation for reversal of multidrug resistance in cancer

Virus-mimetic polymeric micelles for targeted siRNA delivery

(2010) Xiao-Bing Xiong et al.   BIOMATERIALS

The siRNA targeted to mdr1b and mdr1a mRNAs in vivosensitizes murine lymphosarcoma to chemotherapy

(2010) Olga A Patutina et al.   BMC CANCER

Cationic polymer-mediated small interfering RNA delivery for P-glycoprotein down-regulation in tumor cells

(2010) Meysam Abbasi et al.   CANCER

Proteasome inhibitor MG132 reverses multidrug resistance of gastric cancer through enhancing apoptosis and inhibiting P-gp

(2010) Yafei Zhang et al.   CANCER BIOLOGY & THERAPY

Multiple Drug Resistance Mechanisms in Cancer

(2010) Bruce C. Baguley   MOLECULAR BIOTECHNOLOGY

The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance

(2009) Yogesh B. Patil et al.   BIOMATERIALS

Simultaneous targeting ofMCL1andABCB1as a novel strategy to overcome drug resistance in human leukaemia

(2009) Min Ji et al.   BRITISH JOURNAL OF HAEMATOLOGY

ABC Efflux Pump-Based Resistance to Chemotherapy Drugs

(2009) Paul D. W. Eckford et al.   CHEMICAL REVIEWS

Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel

(2009) Changxing Liu et al.   JOURNAL OF CONTROLLED RELEASE

siRNA-based targeting of antiapoptotic genes can reverse chemoresistance in P-glycoprotein expressing chondrosarcoma cells

(2009) Dae Kim et al.   Molecular Cancer

In vivo down-regulation of mouse brain capillary P-glycoprotein: A preliminary investigation

(2009) Christina Fuest et al.   NEUROSCIENCE LETTERS

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

In vivoReversal of P-Glycoprotein-Mediated Multidrug Resistance by Efficient Delivery of StealthTMRNAi

(2008) Hong Xiao et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells

(2008) Hua Zhu et al.   BIOCHEMICAL PHARMACOLOGY

Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity

(2008) Arkadi Zintchenko et al.   BIOCONJUGATE CHEMISTRY

Biodegradable amphiphilic poly(ethylene oxide)-block-polyesters with grafted polyamines as supramolecular nanocarriers for efficient siRNA delivery

(2008) Xiao-Bing Xiong et al.   BIOMATERIALS

Formulation and Delivery of siRNA by Oleic Acid and Stearic Acid Modified Polyethylenimine

(2008) Aws Alshamsan et al.   MOLECULAR PHARMACEUTICS

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

(2008) Mark E. Kleinman et al.   NATURE

RPN2 gene confers docetaxel resistance in breast cancer

(2008) Kimi Honma et al.   NATURE MEDICINE

Complete In Vivo Reversal of the Multidrug Resistance Phenotype by Jet-injection of Anti-MDR1 Short Hairpin RNA-encoding Plasmid DNA

(2007) Ulrike Stein et al.   MOLECULAR THERAPY