Histone deacetylase inhibitors (HDACIs). Structure-activity relationships: history and new QSAR perspectives

Identification and characterization of novel sirtuin inhibitor scaffolds

(2009) Brandi D. Sanders et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Identification of a cell-active non-peptide sirtuin inhibitor containing N-thioacetyl lysine

(2009) Takayoshi Suzuki et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition of Human Sirtuins by in Situ Generation of an Acetylated Lysine−ADP−Ribose Conjugate

(2009) Tomomi Asaba et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Identification of proteases and their types

(2008) Hong-Bin Shen et al.   ANALYTICAL BIOCHEMISTRY

ProtIdent: A web server for identifying proteases and their types by fusing functional domain and sequential evolution information

(2008) Kuo-Chen Chou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

An in-depth analysis of the biological functional studies based on the NMR M2 channel structure of influenza A virus

(2008) Ri-Bo Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug–drug complex networks

(2008) Francisco J. Prado-Prado et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: Histone deacetylase inhibition and in-cell activities

(2008) Antonello Mai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design and campaign synthesis of pyridine-based histone deacetylase inhibitors

(2008) David M. Andrews et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator

(2008) Sonia Lain et al.   CANCER CELL

Chemistry, Biology, and QSAR Studies of Substituted Biaryl Hydroxamates and Mercaptoacetamides as HDAC Inhibitors—Nanomolar-Potency Inhibitors of Pancreatic Cancer Cell Growth

(2008) Alan P. Kozikowski et al.   ChemMedChem

Chemical Origins of Isoform Selectivity in Histone Deacetylase Inhibitors

(2008) Alan Kozikowski et al.   CURRENT PHARMACEUTICAL DESIGN

Recent Advances in QSAR and Their Applications in Predicting the Activities of Chemical Molecules, Peptides and Proteins for Drug Design

(2008) Qi-Shi Du et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

GPCR-CA: A cellular automaton image approach for predicting G-protein-coupled receptor functional classes

(2008) Xuan Xiao et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Histone Deacetylase Inhibitors: From Bench to Clinic

(2008) Marielle Paris et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Series of Potent and Selective, Triazolylphenyl-Based Histone Deacetylases Inhibitors with Activity against Pancreatic Cancer Cells andPlasmodium falciparum

(2008) Yufeng Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Trithiocarbonates as a Novel Class of HDAC Inhibitors: SAR Studies, Isoenzyme Selectivity, and Pharmacological Profiles

(2008) Florian Dehmel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure–Activity Studies on Splitomicin Derivatives as Sirtuin Inhibitors and Computational Prediction of Binding Mode

(2008) Robert C. Neugebauer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Biochemical characterization of Plasmodium falciparum Sir2, a NAD+-dependent deacetylase

(2008) Subhra Prakash Chakrabarty et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Cell-PLoc: a package of Web servers for predicting subcellular localization of proteins in various organisms

(2008) Kuo-Chen Chou et al.   Nature Protocols

Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect

(2008) E Lara et al.   ONCOGENE

Proteomics, networks and connectivity indices

(2008) Humberto González-Díaz et al.   PROTEOMICS

Class II-selective histone deacetylase inhibitors. Part 2: Alignment-independent GRIND 3-D QSAR, homology and docking studies

(2007) Rino Ragno et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Identification of ligand features essential for HDACs inhibitors by pharmacophore modeling

(2007) Ya-dong Chen et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING