Development of reversible glutamine conjugate of methotrexate for enhanced brain delivery

First demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo

(2013) Kaidi Zhou et al.   BIOCHEMICAL PHARMACOLOGY

Erratum to: Design, Synthesis and Brain Uptake of LAT1-Targeted Amino Acid Prodrugs of Dopamine

(2013) Lauri Peura et al.   PHARMACEUTICAL RESEARCH

Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1

(2013) E. G. Geier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug Transport across the Blood–Brain Barrier

(2012) William M Pardridge   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

High dose methotrexate chemotherapy: pharmacokinetics, folate and toxicity in osteosarcoma patients

(2011) Laila Holmboe et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Treatment of Rat Brain Tumors Using Sustained-Release of Camptothecin from Poly(lactic-co-glycolic acid) Microspheres in a Thermoreversible Hydrogel

(2010) Tetsuya Ozeki et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Transnasal Delivery of Methotrexate to Brain Tumors in Rats: A New Strategy for Brain Tumor Chemotherapy

(2010) Tomotaka Shingaki et al.   MOLECULAR PHARMACEUTICS

Synthesis, uptake mechanism characterization and biological evaluation of 18F labeled fluoroalkyl phenylalanine analogs as potential PET imaging agents

(2010) Limin Wang et al.   NUCLEAR MEDICINE AND BIOLOGY

Lipophilic pyrazinoic acid amide and ester prodrugs

(2009) Marta Filipa Simões et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Approaches to transport therapeutic drugs across the blood–brain barrier to treat brain diseases

(2009) Reinhard Gabathuler   NEUROBIOLOGY OF DISEASE

A polarized localization of amino acid/carnitine transporter B0,+ (ATB0,+) in the blood–brain barrier

(2008) Magdalena Czeredys et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS