Synthesis, biological evaluation, and molecular modeling studies of new 1,3,4-oxadiazole- and 1,3,4-thiadiazole-substituted 4-oxo-4H-pyrido[1,2-a]pyrimidines as anti-HIV-1 agents

Retroviral intasome assembly and inhibition of DNA strand transfer

(2010) Stephen Hare et al.   NATURE

Pharmacokinetics and Safety of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor, in Healthy Volunteers

(2009) S. Min et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

3-Hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylates—A new class of HIV-1 integrase inhibitors

(2009) Monica Donghi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1,3,4-Oxadiazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 2: SAR of the C5 position

(2009) Brian A. Johns et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Potential for New Antiretrovirals to Address Unmet Needs in the Management of HIV-1 Infection

(2008) Graeme Moyle et al.   AIDS PATIENT CARE AND STDS

Drug resistance profiles for the HIV integrase gene in patients failing raltegravir salvage therapy*

(2008) C Charpentier et al.   HIV MEDICINE