4.2 Article

Chemical composition and antimicrobial activity of the volatile oils of Geranium sanguineum L. and G. robertianum L. (Geraniaceae)

Journal

MEDICINAL CHEMISTRY RESEARCH
Volume 21, Issue 5, Pages 601-615

Publisher

BIRKHAUSER BOSTON INC
DOI: 10.1007/s00044-011-9565-9

Keywords

Geraniaceae; Geranium sanguineum; Geranium robertianum; Essential oil composition; Antimicrobial activity

Funding

  1. Ministry of Science and Technological Development of Serbia [172061]

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Volatile compounds of Geranium sanguineum and G. robertianum were isolated by hydrodistillation, analyzed in detail by GC and GC/MS and screened for their in vitro antibacterial and antifungal activity in a microdilution assay. In total, 304 constituents were identified, representing more than 90% of the isolated oils. The volatiles of G. sanguineum have been studied for the first time in this study. The antimicrobial assay showed a strong activity of the G. robertianum oil against Escherichia coli and Aspergillus fumigatus. Micrococcus flavus and A. fumigatus were the most susceptible strains to G. sanguineum oil.

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