Article
Engineering, Biomedical
Antony L. Palmer, David Nash, Wojciech Polak, Sarah Wilby
Summary: This study evaluated the differences between the new Gafchromic EBT4 film and the current EBT3 film for radiotherapy dosimetry. The results showed that EBT4 had more favorable characteristics for radiation dosimetry compared to EBT3, with improved signal-to-noise ratio. EBT4 provided better agreement with the planned doses and showed equivalent or smaller difference in measured dose compared to EBT3.
PHYSICS IN MEDICINE AND BIOLOGY
(2023)
Article
Nuclear Science & Technology
Maria A. Piliero, Francesco Pupillo, Stefano Presilla
Summary: In this study, the Konica Minolta CM-700d spectrophotometer was characterized as a portable device for radiation dosimetry using EBT3 GAFchromic films. The results showed high stability and reproducibility of colour measurements, with a dose measurement accuracy of 2% and faster readout speed.
RADIATION MEASUREMENTS
(2022)
Review
Chemistry, Multidisciplinary
Pierluigi Casolaro
Summary: Radiochromic films are widely used for two-dimensional dose verification in photon, electron, and proton therapy treatments, covering a wide range of dose levels. Understanding the characteristics, principles, and reading techniques of radiochromic films is crucial for fully utilizing this versatile radiation detection system.
APPLIED SCIENCES-BASEL
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ahtesham Ullah Khan, Jeff Radtke, Clifford Hammer, Julia Malyshev, Brett Morris, Carri Glide-Hurst, Larry Dewerd, Wesley Culberson, Adam Bayliss
Summary: This study investigated the pulse characteristics of a 6 MV photon beam during PRDR irradiations on a commercial linac. The feasibility of using EBT3 radiochromic film for use in IMRT QA was also investigated by comparing its response to a commercial diode array phantom.
JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS
(2023)
Article
Engineering, Biomedical
Daniel Sanchez-Parcerisa, Irene Sanz-Garcia, Paula Ibanez, Samuel Espana, Andrea Espinosa, Carolina Gutierrez-Neira, Alfonso Lopez, Juan Antonio Vera, Alejandro Mazal, Luis Mario Fraile, Jose Manuel Udias
Summary: Passive dosimetry with radiochromic films is widely used in proton radiotherapy, but film under-response for low-energy protons must be accounted and corrected for. A meta-analysis was performed on existing data to integrate different types of films, showing a linear decrease of relative efficiency with increasing LET, with no remarkable differences between the three types of films analyzed. Direct measurements with a 10 MeV proton beam further supported the findings.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Chemistry, Physical
Apoorva Mittal, Gopishankar Natanasabapathi, Akhilesh Verma, Pratik Kumar
Summary: A novel polymer based radiochromic film has been developed in this study, showing excellent dose response, energy and dose rate dependence, and post-irradiation stability. These films exhibit promising performance compared with commercial films under different parameters, and have great potential for medical radiation dosimetry.
RADIATION PHYSICS AND CHEMISTRY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Scott Hoopingarner, Mark Oldham, Justus Adamson, Kawtar Lakrad
Summary: This study investigates the combination of ClearView dosimeters and the DLOS telecentric optical-CT scanner. Simple benchmark irradiations demonstrate that ClearView/DLOS accurately recreates and measures relative 3D dose within non-artifact regions (>1 cm away from walls). Application to SIMT SRS deliveries shows the viability of the system for comprehensive 3D verification of complex treatment deliveries and confirms the treatment planning system dose distribution. The DLOS/ClearView system is highly effective for SIMT irradiations, with passing rates of >95% using 3%/2 mm gamma criteria.
Article
Multidisciplinary Sciences
Mattias Klaus Juhl, Binesh Puthen Veettil, Giuseppe Scardera, David Neil Roger Payne
Summary: This paper investigates the use of consumer flatbed scanners for monitoring solar cell precursors, finding that contact image sensors are more suitable. The scanners' ability to monitor texture variation in samples was successfully demonstrated.
SCIENTIFIC REPORTS
(2022)
Review
Polymer Science
Yves De Deene
Summary: Gel dosimetry is a method used to validate the radiation dose distribution in high-precision radiotherapy for cancer patients. It involves using gel dosimeters that undergo oxidation or color change upon exposure to ionizing radiation. There are three classes of gel dosimeters: Fricke gel dosimeters, radiochromic gel dosimeters, and polymer gel dosimeters, which are read out using quantitative magnetic resonance imaging (MRI) or X-ray CT. With the introduction of the MR-Linac, the ability to acquire dose maps during radiation has been demonstrated, but new challenges have emerged.
Article
Optics
Yunxiao He, Wei Hong, Jianfei Hua, Wei Qi, Zhimeng Zhang, Gang Li, Bo Cui, Feng Lu, Zhigang Deng, Shukai He, Jingqin Su, Weimin Zhou, Wei Lu, Yuqiu Gu
Summary: This novel method utilizes the radiochromic effect to measure the fluence distribution of intense short laser pulses, enabling large detection areas and high spatial resolution, suitable for radiochromic films.
Article
Radiology, Nuclear Medicine & Medical Imaging
Connor Mcnairn, Iymad Mansour, Bryan Muir, Rowan M. Thomson, Sangeeta Murugkar
Summary: This work aims to develop a new approach for high spatial resolution dosimetry using Raman micro-spectroscopy scanning of radiochromic film. The study achieved high resolution in dose response of the film, down to 0.03 Gy, and generated calibration curves for dose estimation. The total uncertainty in dose estimation ranged from [6-9]% for doses between 0.5-50 Gy, with experimental uncertainty contributing [5-8]%, and fitting uncertainty contributing [2.5-4.5]%.
Article
Chemistry, Multidisciplinary
Joseph R. Newton, Maxwell Recht, Joseph A. Hauger, Gabriel Segarra, Chase Inglett, Pedro A. Romo, John Adamovics
Summary: The article describes the current practice of patient-specific quality assurance using ion chambers or diode arrays, as well as the development and testing of a 3D radiochromic dosimeter. Three promising dosimeter formulations were studied to find one that retained dose sensitivity upon multiple re-irradiations, making it an ideal choice for further evaluation as a 3D dosimeter.
APPLIED SCIENCES-BASEL
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hugo Bouchard, Ilias Billas, Anna Subiel, Simon Duane
Summary: This study introduces a new multichannel method for correcting systematic thickness disturbances in radiation dosimetry, showing high precision in relevant applications. Utilizing the eigencolor ratio technique, the method efficiently corrects for thickness variations and dark spots that cause errors in single-channel distributions. The proposed method yields standard uncertainties ranging from 0.8% to 1.9% in relative dosimetry, with the potential to achieve uncertainty levels between 0.3% and 0.6% with repeated measurements.
Article
Radiology, Nuclear Medicine & Medical Imaging
Kevin Liu, Patrik Goncalves Jorge, Ramesh Tailor, Raphael Moeckli, Emil Schuler
Summary: This study evaluated the performance of Gafchromic EBT3 film under various measurement conditions to simplify but enhance film dosimetry. The results showed that scanning the film within a certain time window and using a standard calibration curve introduced a maximum error of 2% over a dose range of 1-40 Gy. The film response was influenced by the film-read delay, film batch, scanner type, and beam energy.
Article
Chemistry, Physical
Ebrahim Farajzadeh, Sedigheh Sina
Summary: This study proposed a reliable method for blood irradiation dosimetry using a Fricke Xylenol Gel dosimeter, which demonstrated high accuracy and precision within the dose range of 5-50 Gy. The dosimeter developed in this study has acceptable properties to control the quality of blood radiation dosimetry, showing potential for preventing transplant complications against the host.
RADIATION PHYSICS AND CHEMISTRY
(2021)
Article
Multidisciplinary Sciences
Paola Anna Jablonska, Ricardo Diez-Valle, Jaime Gallego Perez-Larraya, Marta Moreno-Jimenez, Miguel Angel Idoate, Leire Arbea, Sonia Tejada, Maria Reyes Garcia de Eulate, Luis Ramos, Javier Arbizu, Pablo Dominguez, Jose Javier Aristu
Article
Oncology
David Buechser, Francisco Casquero, Jose Maria Espinosa, Fernando Perez, Pablo Minguez, Lorea Martinez-Indart, Fernan Suarez, Alba Gonzalez, Jon Cacicedo, Inigo San Miguel, Alejandro Maleta, Antonio Gomez-Caamano, Pedro Bilbao, Alfonso Gomez-Iturriaga
RADIOTHERAPY AND ONCOLOGY
(2019)
Article
Multidisciplinary Sciences
Naiara Martinez-Velez, Marc Garcia-Moure, Miguel Marigil, Marisol Gonzalez-Huarriz, Montse Puigdelloses, Jaime Gallego Perez-Larraya, Marta Zalacain, Lucia Marrodan, Maider Varela-Guruceaga, Virginia Laspidea, Jose Javier Aristu, Luis Isaac Ramos, Sonia Tejada-Solis, Ricardo Diez-Valle, Chris Jones, Alan Mackay, Jose A. Martinez-Climent, Maria Jose Garcia-Barchino, Eric Raabe, Michelle Monje, Oren J. Becher, Marie Pierre Junier, Elias A. El-Habr, Herve Chneiweiss, Guillermo Aldave, Hong Jiang, Juan Fueyo, Ana Patino-Garcia, Candelaria Gomez-Manzano, Marta M. Alonso
NATURE COMMUNICATIONS
(2019)
Article
Multidisciplinary Sciences
Gabriel Reynes-Llompart, Aida Sabate-Llobera, Elena Llinares-Tello, Josep M. Marti-Climent, Cristina Gamez-Cenzano
SCIENTIFIC REPORTS
(2019)
Article
Oncology
Alfonso Gomez-Iturriaga, David Buchser, Esther Mayrata, Inigo San Miguel, Alba Gonzalez, Fernan Suarez, Lorea Martinez-Indart, Pablo Minguez, Jose Espinosa, Fernando Perez, Jon Cacicedo, Francisco Casquero
RADIOTHERAPY AND ONCOLOGY
(2020)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Josep M. Marti-Climent
REVISTA ESPANOLA DE MEDICINA NUCLEAR E IMAGEN MOLECULAR
(2020)
Article
Engineering, Biomedical
L. I. Ramos Garcia, J. F. Perez-Azorin, M. Anguiano, A. M. Lallena
Summary: In this study, a Monte Carlo scheme is proposed to calculate the collection efficiency for any ionization chamber geometry. Results show that the method is stable against changes in different parameters and can be a useful tool for calculating collection efficiencies of ionization chambers.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Oncology
Alejandro Garcia-Consuegra, Marta Gimeno Morales, Mauricio Cambeiro, Luca Tagliaferri, Gyoergy Kovacs, Erik Van Limbergen, Luis Ramos, Jose Manuel Arnaiz, Juan Alcalde, Fernando Lecanda, Rafael Martinez-Monge
Summary: The HNS working group analyzed 227 head and neck cancer patients treated with surgery and adjuvant HDR brachytherapy, finding STN incidence of 12.3% and ORN of 5.7%. It is recommended to avoid CTVs over 15cm(3) and total EQD2-DVH TV100 doses exceeding 87Gy in unirradiated patients, as well as limit Mandible(2cm3) irradiation to 61Gy.
RADIOTHERAPY AND ONCOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Veronica Moran, Elena Prieto, Lidia Sancho, Macarena Rodriguez-Fraile, Leticia Soria, Arantxa Zubiria, Josep M. Marti-Climent
Article
Radiology, Nuclear Medicine & Medical Imaging
Elena Prieto, Maria Jose Garcia-Velloso, Jesus Damaso Aquerreta, Juan Jose Rosales, Juan Fernando Bastidas, Ignacio Soriano, Leticia Irazola, Paula Rodriguez-Otero, Gemma Quincoces, Josep Maria Marti-Climent
Summary: The study found that using an ultra-low dose CT in PET/CT scans can accurately perform attenuation correction and significantly reduce the radiation dose received by patients. In most cases, the variation of PET contrast recovery coefficients is within +/-1.2%, and despite the poorer image quality of the ultra-low dose CT, it can still accurately identify bone lesions at a high rate.
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
(2021)
Article
Oncology
Jose Manuel Lopez-Vega, Isabel Alvarez, Antonio Anton, Jose Juan Illarramendi, Antonio Llombart, Valentina Boni, Maria Jose Garcia-Velloso, Josep Maria Marti-Climent, Luis Pina, Jesus Garcia-Foncillas
Summary: This study showed that bevacizumab caused structural and functional changes in the blood vessels of breast tumors and significantly slowed tumor growth. By evaluating changes in vascular endothelial growth factor receptor (VEGFR)-2p levels, potential predictive biomarkers for response to neoadjuvant bevacizumab therapy in breast cancer patients were identified through serial imaging techniques and molecular gene profiling.
Article
Radiology, Nuclear Medicine & Medical Imaging
Jose Fernando Perez Azorin, Jordi Saez, Luis Isaac Ramos Garcia, Victor Hernandez
Summary: The double-stacked design of the Halcyon multileaf collimator (MLC) presents challenges for treatment planning systems (TPSs), as the Eclipse TPS does not adequately model the leaf trailing effect. Our study investigates and reports dose discrepancies caused by these limitations in clinical plans and explores ways to mitigate and avoid these discrepancies.
Article
Multidisciplinary Sciences
Elena Prieto, Leticia Irazola, Maria Collantes, Margarita Ecay, Teresa Cuenca, Josep Ma Marti-Climent, Ivan Penuelas
Summary: The aim of this study was to evaluate the performance of the U-SPECT6/CT E-class system for preclinical imaging and demonstrate its suitability for simultaneous multi-animal and multi-isotope imaging with reliable quantitative accuracy. The results showed that the system has good sensitivity and spatial resolution, providing quantitative images that are suitable for multi-mouse and multi-isotope acquisitions.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Esther Mayrata, Jose Maria Espinosa, David Buchser, Francisco Casquero, Fernan Suarez, Alba Gonzalez, Pablo Minguez, Jose Fernando Perez, Inigo San Miguel, Jon Cacicedo, Alfonso Gomez-Iturriaga
Summary: Salvage HDR-BT 12 x 2 is a feasible and well-tolerated treatment with acceptable toxicity rates for men with locally recurrent prostate cancer who failed after HDR-BT with 19 Gy. PSA kinetics and cancer control after salvage treatment suggest that this strategy might be efficacious in this clinical setting.
JOURNAL OF CONTEMPORARY BRACHYTHERAPY
(2021)