The NineTeen Complex (NTC) and NTC-associated proteins as targets for spliceosomal ATPase action during pre-mRNA splicing

Structural and Functional Insights into the N-Terminus of Schizosaccharomyces pombe Cdc5

(2014) Scott E. Collier et al.   BIOCHEMISTRY

Remodeling of U2-U6 snRNA helix I during pre-mRNA splicing by Prp16 and the NineTeen Complex protein Cwc2

(2014) Rebecca Hogg et al.   NUCLEIC ACIDS RESEARCH

The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome

(2014) A. M. Wlodaver et al.   RNA

Rapid screening of yeast mutants with reporters identifies new splicing phenotypes

(2013) Natacha Dreumont et al.   FEBS Journal

Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system

(2013) J.-B. Fourmann et al.   GENES & DEVELOPMENT

Splicing fidelity

(2013) Prakash Koodathingal et al.   RNA Biology

Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system

(2013) T. Ohrt et al.   RNA

Functional roles of protein splicing factors

(2012) Hsin‑Chou Chen et al.   BIOSCIENCE REPORTS

Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre

(2012) Nicolas Rasche et al.   EMBO JOURNAL

Saccharomyces cerevisiaeNineTeen Complex (NTC)-associated Factor Bud31/Ycr063w Assembles on Precatalytic Spliceosomes and Improves First and Second Step Pre-mRNA Splicing Efficiency

(2012) Debjani Saha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Link of NTR-Mediated Spliceosome Disassembly with DEAH-Box ATPases Prp2, Prp16, and Prp22

(2012) Hsin-Chou Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

The Interaction of Prp2 with a Defined Region of the Intron Is Required for the First Splicing Reaction

(2012) H.-L. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

RNA helicases in splicing

(2012) Olivier Cordin et al.   RNA Biology

Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS

(2012) T. Ohrt et al.   RNA

Pre-mRNA splicing in disease and therapeutics

(2012) Ravi K. Singh et al.   TRENDS IN MOLECULAR MEDICINE

The function of the NineTeen Complex (NTC) in regulating spliceosome conformations and fidelity during pre-mRNA splicing

(2010) Rebecca Hogg et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Brr2p RNA helicase with a split personality: insights into structure and function: Figure 1

(2010) Daniela Hahn et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Splicing Factor Cwc22 Is Required for the Function of Prp2 and for the Spliceosome To Escape from a Futile Pathway

(2010) T.-C. Yeh et al.   MOLECULAR AND CELLULAR BIOLOGY

The DEAH Box ATPases Prp16 and Prp43 Cooperate to Proofread 5′ Splice Site Cleavage during Pre-mRNA Splicing

(2010) Prakash Koodathingal et al.   MOLECULAR CELL

Metal binding and substrate positioning by evolutionarily invariant U6 sequences in catalytically active protein-free snRNAs

(2010) C. Lee et al.   RNA

DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps

(2010) C.-K. Tseng et al.   RNA

Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing

(2010) R. M. Lardelli et al.   RNA

The Prp19 WD40 Domain Contains a Conserved Protein Interaction Region Essential for Its Function

(2010) Craig W. Vander Kooi et al.   STRUCTURE

RNA helicases at work: binding and rearranging

(2010) Eckhard Jankowsky   TRENDS IN BIOCHEMICAL SCIENCES

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Cwc25 Is a Novel Splicing Factor Required after Prp2 and Yju2 To Facilitate the First Catalytic Reaction

(2009) Y.-F. Chiu et al.   MOLECULAR AND CELLULAR BIOLOGY

The Evolutionarily Conserved Core Design of the Catalytic Activation Step of the Yeast Spliceosome

(2009) Patrizia Fabrizio et al.   MOLECULAR CELL

Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components

(2009) Zbigniew Warkocki et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing

(2009) J. C. McGrail et al.   NUCLEIC ACIDS RESEARCH

A structural analysis of the group II intron active site and implications for the spliceosome

(2009) K. S. Keating et al.   RNA

Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps

(2009) M. A. Mefford et al.   RNA

The role of Snu114p during pre-mRNA splicing: Figure 1

(2008) Lily Novak Frazer et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

“Nought May Endure but Mutability”: Spliceosome Dynamics and the Regulation of Splicing

(2008) Duncan J. Smith et al.   MOLECULAR CELL

A Conformational Rearrangement in the Spliceosome Sets the Stage for Prp22-Dependent mRNA Release

(2008) Beate Schwer   MOLECULAR CELL