Article
Polymer Science
Linas Kudrevicius, Evelina Jaselske, Diana Adliene, Viktoras Rudzianskas, Andrius Radziunas, Arimantas Tamasauskas
Summary: Highly precise dose delivery to brain diseases using recent stereotactic techniques is crucial, requiring quality assurance measures. This paper discusses the use of two dosimetry methods for treatment dose verification in stereotactic radiosurgery treatments.
Article
Radiology, Nuclear Medicine & Medical Imaging
Borna Maraghechi, Taeho Kim, Timothy J. Mitchell, S. Murty Goddu, Joe Dise, James A. Kavanaugh, Jacqueline E. Zoberi, Sasa Mutic, Nels C. Knutson
Summary: The study showed that using active detector-based quality assurance methods can simplify procedures, save time, and maintain accuracy. Results from annual QA tests on the LGK Icon system demonstrated comparable outcomes between filmless techniques and radiochromic film techniques.
JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Tae Hoon Kim, Hye Jeong Yang, Jae Young Jeong, Thomas Schaarschmidt, Yong Kyun Kim, Hyun-Tai Chung
Summary: This study calculated the volume averaging effect using scintillation detectors based on a gamma knife dose distribution. The results showed that the output factors measured by the scintillation detectors were consistent with a commercial synthetic micro-diamond detector and recent studies.
Article
Radiology, Nuclear Medicine & Medical Imaging
Wille Hager, Vaiva Kaveckyte, Hamza Benmakhlouf
Summary: Radiosurgery using LGK Icon is a common technique for treating intracranial lesions. TRS-483 provides guidelines for small-field dosimetry correction factors. Results showed that ABS phantom underestimated dose-rate by at least 1%, while SW phantom is less likely to underestimate by more than 1%. ABS phantom is not recommended for LGK reference dosimetry.
Article
Engineering, Multidisciplinary
T. Medjadj, A. I. Ksenofontov, V. A. Klimanov, A. V. Dalechina, Y. S. Kirpichev
Summary: This study validates the penEasy Monte Carlo model for Leksell Gamma Knife Perfexion through experimental measurements, showing excellent agreement between penEasy and EBT3 results. The differences in output factors and dose profiles were found to be minimal, indicating the potential for clinical application in radiotherapy.
INSTRUMENTS AND EXPERIMENTAL TECHNIQUES
(2021)
Article
Clinical Neurology
Beong Ik Hur, Seong Jin Jin, Gyeong Rip Kim, Jong Hyeok Kwak, Young Ha Kim, Sang Weon Lee, Soon Ki Sung
Summary: This study investigated the validity of the 5th generation Gamma Knife Perfexion's Leksell Gamma plan 10.1.1 system with a modified variable ellipsoid modeling technique (VEMT), showing consistent results. The modified VEMT method can be used as a stable tool for testing and operating the Gamma Knife Perfexion treatment planning system.
JOURNAL OF KOREAN NEUROSURGICAL SOCIETY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yue-Houng Hu, Susannah Hickling, Jing Qian, C. Robert Blackwell, Luke B. McLemore, Erik J. Tryggestad
Summary: This study mainly evaluated the dosimetry and targeting accuracy of the Leksell Gamma Knife Icon unit (IU) for both invasive frame and frameless treatment workflows. Measurements and tests were conducted using EBT3 film, CBCT and CT-based methods, and a rigid phantom. The results showed that the IU treatment deliveries had reliable dosimetric and geometric accuracy, and the commissioning of IU for clinical use was confirmed.
JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Nikola Segedin, Hrvoje Hrsak, Sanja Dolanski Babic, Slaven Jurkovic
Summary: The purpose of this study is to calculate volume averaging correction factors for detectors used in Gamma Knife's dosimetry and determine its impact on the field output correction factor. Simulations were conducted using an elliptical dose model and compared with Leksell GammaPlan calculations. Volume averaging correction factors were determined for different detectors, and the dominant contribution of volume averaging to the field output correction factor was demonstrated.
JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS
(2023)
Article
Chemistry, Inorganic & Nuclear
Lucilio dos Santos Matias, Hamza Benmakhlouf, Maria Doncel, Jonas Johansson, Per Kjall, Hakan Nordstrom, Markus Preston, Per-Erik Tegner
Summary: The aim of this study is to improve the characterization and modeling of the radiation field surrounding the Leksell Gamma Knife & REG;-PerfexionTM. Measurements were taken at various locations in a treatment room to validate the results of a Monte Carlo simulation system. The study shows that Monte Carlo simulations can be used in structural shielding design calculations for the Leksell Gamma Knife.
APPLIED RADIATION AND ISOTOPES
(2023)
Article
Neurosciences
Maneet Gill, Manish Sharma, Raj Ratan
Summary: Gamma knife radiosurgery was developed based on the principles of stereotactic radiosurgery proposed by Swedish physician Lars Leksell. The Perfexion model has been widely used in India but has now been replaced with the newer ICON model, which incorporates Cone-Beam Computed Tomography (CBCT) for non-invasive and accurate skull immobilization. Despite some challenges, the use of the ICON model has been successful in frameless gamma knife surgeries in around 25% of planned patients. Rating: 8/10.
Article
Radiology, Nuclear Medicine & Medical Imaging
Yona Choi, Kook Jin Chun, Eun San Kim, Jungbae Bahng, Hye Jeong Yang, Tae Hoon Kim, Gyu Seok Cho, Sang Hyoun Choi, Young Chan Seo, Hyun-Tai Chung
Summary: This study aimed to assess the role and accuracy of k(Qmsr,Q0)(fmsr,fref) values in determining the absorbed dose rates to water in the reference dosimetry of Gamma Knife. The dose rates were measured using three ionization chambers and various correction factors were applied. The study found that the averaged correction factors reduced the variations in dose rates significantly.
Article
Radiology, Nuclear Medicine & Medical Imaging
Hyeong Cheol Moon, Hyun-Tai Chung, Byung Jun Min, Yun-Sik Dho
Summary: This study evaluated the characteristics of three mask fixation methods (Plain, Folded, and Wide) for the Leksell Gamma Knife (LGK) Icon(TM). The results showed that the Folded method is recommended for tight fixation of patients, while the Wide method can be considered if patient comfort is a priority.
JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
David J. Schlesinger, Jason C. Sanders, Donald A. Muller, Hakan Nordstrom, Jason P. Sheehan
Summary: The study characterized the long-term performance of a Gamma Knife Perfexion/Icon unit and used statistical process control (SPC) methods to detect changes in performance at levels lower than existing QA and internal manufacturer performance tolerances. The results showed that changes in positioning behavior could be observed over time, allowing for early identification and possibly prediction of faults beyond control system tolerance.
Article
Nuclear Science & Technology
Wanook Ji, Jong-Bum Kim, Jin-Joo Kim
Summary: This study used peeled-off GafchromicTM EBT3 film to measure the activity distribution of the Ni-63 source and found that absorbed dose increased proportionally to source activity and exposure duration. Low energy beta particles could transport energy into the active layer, and two-dimensional dosimetric distribution was suitable for measuring activity distribution.
NUCLEAR ENGINEERING AND TECHNOLOGY
(2022)
Article
Chemistry, Physical
G. G. Kaarunya Dhevi, Bhaskar Sanyal, V. Prakasan, C. K. Saurabh, S. Gautam
Summary: Radiation dosimetry is crucial for the desired objectives in food radiation processing. The development of inexpensive and easy-to-handle dosimeters operating in the low dose range of 0.1-1 kGy is highly desirable. A leuco crystal violet dye-based radiochromic film with 2,2,2-trichloroethanol as sensitizer was developed, demonstrating a linear dynamic response. The response of the film was assessed using both conventional single channel and novel double channel approaches.
RADIATION PHYSICS AND CHEMISTRY
(2023)