The role of hepatic immune regulation in systemic immunity to viral infection

Neutrophils Recruited to Sites of Infection Protect from Virus Challenge by Releasing Neutrophil Extracellular Traps

(2013) Craig N. Jenne et al.   Cell Host & Microbe

CD39 expression by hepatic myeloid dendritic cells attenuates inflammation in liver transplant ischemia-reperfusion injury in mice

(2013) Osamu Yoshida et al.   HEPATOLOGY

T Cell-Positive Selection Uses Self-Ligand Binding Strength to Optimize Repertoire Recognition of Foreign Antigens

(2013) Judith N. Mandl et al.   IMMUNITY

Immune surveillance by the liver

(2013) Craig N Jenne et al.   NATURE IMMUNOLOGY

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8+ T cells and successful immunotherapy against chronic viral liver infection

(2013) Li-Rung Huang et al.   NATURE IMMUNOLOGY

Liver-Primed Memory T Cells Generated under Noninflammatory Conditions Provide Anti-infectious Immunity

(2013) Jan P. Böttcher et al.   Cell Reports

A Spatially-Organized Multicellular Innate Immune Response in Lymph Nodes Limits Systemic Pathogen Spread

(2012) Wolfgang Kastenmüller et al.   CELL

Intravital Imaging Reveals Limited Antigen Presentation and T Cell Effector Function in Mycobacterial Granulomas

(2011) Jackson G. Egen et al.   IMMUNITY

DAP12 Promotes IRAK-M Expression and IL-10 Production by Liver Myeloid Dendritic Cells and Restrains Their T Cell Allostimulatory Ability

(2011) T. L. Sumpter et al.   JOURNAL OF IMMUNOLOGY

Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus

(2011) Nadine Honke et al.   NATURE IMMUNOLOGY

Acute hepatitis A virus infection is associated with a limited type I interferon response and persistence of intrahepatic viral RNA

(2011) R. E. Lanford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatocyte entry leads to degradation of autoreactive CD8 T cells

(2011) V. Benseler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tonic T cell signalling and T cell tolerance as opposite effects of self-recognition on dendritic cells

(2010) Natalio Garbi et al.   CURRENT OPINION IN IMMUNOLOGY

Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus

(2010) Matteo Iannacone et al.   NATURE

An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells

(2010) Woo-Yong Lee et al.   NATURE IMMUNOLOGY

Prolonged Antigen Presentation Is Required for Optimal CD8+ T Cell Responses against Malaria Liver Stage Parasites

(2010) Ian A. Cockburn et al.   PLoS Pathogens

Virally Infected Mouse Liver Endothelial Cells Trigger CD8+ T-Cell Immunity

(2009) Michaela Kern et al.   GASTROENTEROLOGY

Distinct kinetics and dynamics of cross-presentation in liver sinusoidal endothelial cells compared to dendritic cells

(2009) Anna Schurich et al.   HEPATOLOGY

NOD2 Ligation Subverts IFN-  Production by Liver Plasmacytoid Dendritic Cells and Inhibits Their T Cell Allostimulatory Activity via B7-H1 Up-Regulation

(2009) A. Castellaneta et al.   JOURNAL OF IMMUNOLOGY

B7-H1 on Hepatocytes Facilitates Priming of Specific CD8 T Cells But Limits the Specific Recall of Primed Responses

(2008) Christian Wahl et al.   GASTROENTEROLOGY

Intrahepatic Murine CD8 T-Cell Activation Associates With a Distinct Phenotype Leading to Bim-Dependent Death

(2008) Lauren E. Holz et al.   GASTROENTEROLOGY

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

(2008) Shawn D Blackburn et al.   NATURE IMMUNOLOGY

Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

(2008) J. M. Gardner et al.   SCIENCE