Journal
MEDICAL ENGINEERING & PHYSICS
Volume 32, Issue 6, Pages 653-661Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.medengphy.2010.04.006
Keywords
Finite element; Osteoporosis; Vertebral mechanics; Trabecular mechanics; Multi-scale model; Vertebral compression fracture
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Osteoporotic spinal fractures are a major concern in ageing Western societies. This study develops a multi-scale finite element (FE) model of the osteoporotic lumbar vertebral body to study the mechanics of vertebral compression fracture at both the apparent (whole vertebral body) and micro-structural (internal trabecular bone core) levels. Model predictions were verified against experimental data, and found to provide a reasonably good representation of the mechanics of the osteoporotic vertebral body. This novel modelling methodology will allow detailed investigation of how trabecular bone loss in osteoporosis affects vertebral stiffness and strength in the lumbar spine. (C) 2010 IPEM. Published by Elsevier Ltd. All rights reserved.
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