Journal
MEDICAL CLINICS OF NORTH AMERICA
Volume 95, Issue 4, Pages 723-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.mcna.2011.03.011
Keywords
Gram positive bacteria; Vancomycin; Daptomycin; Linezolid; Quinupristin; Dalfopristin; MRSA; VRE
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An overview of the mechanism of action, dosing, clinical indications, and toxicities of the glycopeptide vancomycin is provided. The emerging gram-positive bacterial resistance to antimicrobials and its mechanisms are reviewed. Strategies to control this emergence of resistance are expected to be proposed. Newer antimicrobial agents that have activity against vancomycin-resistant organisms are now available and play a critical role in the treatment of life-threatening infections.
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