4.4 Article

Antibiotics for Gram-Positive Bacterial Infection: Vancomycin, Teicoplanin, Quinupristin/Dalfopristin, Oxazolidinones, Daptomycin, Telavancin, and Ceftaroline

Journal

MEDICAL CLINICS OF NORTH AMERICA
Volume 95, Issue 4, Pages 723-+

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.mcna.2011.03.011

Keywords

Gram positive bacteria; Vancomycin; Daptomycin; Linezolid; Quinupristin; Dalfopristin; MRSA; VRE

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An overview of the mechanism of action, dosing, clinical indications, and toxicities of the glycopeptide vancomycin is provided. The emerging gram-positive bacterial resistance to antimicrobials and its mechanisms are reviewed. Strategies to control this emergence of resistance are expected to be proposed. Newer antimicrobial agents that have activity against vancomycin-resistant organisms are now available and play a critical role in the treatment of life-threatening infections.

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