Article
Medicine, General & Internal
Zohreh Kazemi, Sara Emamgholipour Sefiddashti, Rajabali Daroudi, Askar Ghorbani, Masud Yunesian, Mohammad Sadegh Hassanvand, Zahra Shahali
Summary: This study investigated the estimation and predictors of hospitalisation expenses and in-hospital mortality for patients who had a stroke in Iranian hospitals through a pervasive, nationwide investigation conducted for the first time.
Article
Medicine, General & Internal
Xiaotong Li, Huiwen Xu, Fang Du, Bin Zhu, Pei Xie, Hankun Wang, Xinxin Han
Summary: This study examines the association between increases in physician volume in primary healthcare facilities and reduced utilisation of hospital outpatient and inpatient services in China. The findings suggest that increasing physician volume in primary healthcare facilities is associated with a decrease in outpatient visits in public hospitals, particularly city-administered hospitals. However, no significant associations were found between primary healthcare physician volume and hospital admissions or outpatient expenses.
Article
Medicine, General & Internal
Xiaoling Yan, Yuanli Liu, Keqin Rao, Jinlei Li
Summary: This study aimed to quantify the relationship between increases in medical expenditures of public hospitals and changes in service use and prices. The study found that service use, rather than prices, appears to be the major driver of increases in medical expenditures in Chinese hospitals.
Article
Medicine, General & Internal
Sarah R. Hill, Nawaraj Bhattarai, Clare L. Tolley, Sarah P. Slight, Luke Vale
Summary: This study examines the willingness-to-pay values of the UK public to prevent medication errors in hospitals. The findings highlight various factors that influence the value and likelihood of willingness-to-pay, and suggest the importance of considering cost-benefit analysis in implementing technology to reduce medication administration errors.
Article
Medicine, General & Internal
Peter Vajda, Katalin Richter, Zsolt Bodrogi, Robert G. Vida, Lajos Botz, Sandor Kovacs, Antal Zemplenyi, Richard Bella, Andras Fittler
Summary: This study aimed to measure the cost elements of FMD implementation and operation in Hungarian hospital pharmacies. It found a significant increase in pharmacist and technician workload at the end of the stabilisation period. The research highlights the impact of decommissioning on workflow involving human resources and IT.
Article
Medicine, General & Internal
Jing Wang, Ying Yang, Luxinyi Xu, Yuan Shen, Xiaotong Wen, Lining Mao, Quan Wang, Dan Cui, Zongfu Mao
Summary: This study evaluated the impact of the first round of the National Centralized Drug Procurement pilot (known as the '4+7' policy) on the use of policy-related original and generic drugs. The findings showed that the policy was effective in promoting generic substitution, reducing drug prices, and containing pharmaceutical costs in China. Additionally, the overall quality of drug use among the Chinese population improved, particularly in primary healthcare settings. However, further policy monitoring is needed to address the increased use of non-winning generic drugs and alternative drugs.
Article
Medicine, General & Internal
Evans Otieku, Ama Pokuaa Fenny, Felix Ankomah Asante, Antoinette Bediako-Bowan, Ulrika Enemark
Summary: This study assesses the cost-effectiveness of an active 30-day surgical site infection (SSI) surveillance mechanism at a teaching hospital in Ghana. The results show that the intervention significantly reduces the risk and costs associated with SSI, making it a simple, cost-effective, sustainable, and adaptable strategy.
Article
Medicine, General & Internal
Eusebio Castano-Riera, Manuel Ridao, Julian Librero, Natalia Martinez-Lizaga, Micaela Comendeiro-Maaloe, Ester Angulo-Pueyo, Salvador Peiro, Enrique Bernal-Delgado
Summary: This study provides new evidence on the geographical variation in tonsils surgery in children over time in the context of the Spanish National Health System. The study found persistent variations with an increase in rates and risk of tonsillectomy with adenoidectomy (T&A) and a stagnation of tonsillectomies alone (T). The majority of the variation was explained at the healthcare areas (HCAs) level.
Article
Medicine, General & Internal
Radoslav Zinoviev, Harlan M. Krumholz, Richard Ciccarone, Rick Antle, Howard P. Forman
Summary: The study aimed to create a reliable and publicly available composite score of hospital financial stability by evaluating hospital financial data, selecting key variables, assigning weights, and ultimately constructing the YHFS score.
Article
Medicine, General & Internal
Shohei Okamoto, Kazuki Kamimura, Kohei Komamura
Summary: This study examines the determinants of vaccine hesitancy, reasons for hesitation, and the potential effectiveness of vaccine passports in mitigating vaccine hesitancy. The research findings indicate that concerns about vaccine safety and side effects are major reasons for vaccine hesitancy, and younger age, lower socioeconomic status, and weaker COVID-19 fear are associated with vaccine hesitancy. The implementation of vaccine passports and the easing of public health restrictions are found to increase vaccine acceptance rates.
Article
Medicine, General & Internal
Atsushi Miyawaki, Ryo Ikesu, Yasuharu Tokuda, Rei Goto, Yasuki Kobayashi, Kazuaki Sano, Yusuke Tsugawa
Summary: This study aimed to investigate the use and factors associated with low-value care in Japan. The study utilized a multicentre observational design and claims data from 242 large acute care hospitals in Japan. The findings revealed that approximately 7.5% of patients received low-value care services based on the broader definition, while about 4.9% received such services based on the narrower definition. There was no significant change in the prevalence of low-value services between 2015 and 2019. Factors such as hospital size, age, sex, and comorbidities were associated with the likelihood of receiving low-value care.
Article
Public, Environmental & Occupational Health
Yuan-jin Zhang, Yan Ren, Quan Zheng, Jing Tan, Ming-hong Yao, Yun-xiang Huang, Xia Zhang, Kang Zou, Shao-yang Zhao, Xin Sun
Summary: The pilot National Centralized Drug Procurement (NCDP) program implemented by the Chinese government has successfully reduced drug prices and improved affordability of medicines, benefiting cancer patients. The implementation of NCDP policy led to significant decreases in total expenditures, drug expenditures, and non-drug-related expenditures per inpatient admission.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Oncology
Eric C. Barat, Marianne L. E. Arrii, Annaelle Soubieux-Bourbon, Mikael Daouphars, Remi Varin, Patrick R. Tilleul
Summary: This study investigates the cost and time effectiveness of different administration methods of trastuzumab. The results show that using BSIV in combination therapy can save costs, but increases waiting time for patients. On the other hand, using HSC in monotherapy achieves greater cost savings and time efficiency.
Article
Clinical Neurology
Oliver Y. Tang, Krissia M. Rivera Perla, Rachel K. Lim, James S. Yoon, Robert J. Weil, Steven A. Toms
Summary: Research found that in more competitive markets, hospitals charged higher fees for patients undergoing in-hospital cranial procedures. However, this did not result in increased inpatient costs, except for CSF diversion surgery. Increased competition did not lead to significant improvements in clinical outcomes, except for a potential survival benefit for brain tumor surgery.
JOURNAL OF NEUROSURGERY
(2021)
Article
Gastroenterology & Hepatology
Kunichika Matsumoto, Yinghui Wu, Shigeru Fujita, Kanako Seto, Yosuke Hatakeyama, Ryo Onishi, Tomonori Hasegawa
Summary: The study revealed that the disease burden of liver diseases in Japan has been decreasing for the past 15 years, particularly for viral hepatitis, cirrhosis, and liver cancer. Conversely, the disease burden of alcoholic liver disease and nonalcoholic steatohepatitis (NASH) has been increasing.
ANNALS OF HEPATOLOGY
(2021)
Article
Health Care Sciences & Services
Mao Yanagisawa, Daniel M. Blumenthal, Hirotaka Kato, Kosuke Inoue, Yusuke Tsugawa
Summary: This study found that industry payments to cardiologists for antiplatelet drugs were associated with higher healthcare spending on cardiac procedures, diagnostic cardiac catheterization volumes, and rates of coronary stenting. Further research is needed to determine if these associations are causal.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Editorial Material
Health Care Sciences & Services
Atsushi Miyawaki, Yusuke Tsugawa
BMJ QUALITY & SAFETY
(2022)
Review
Cardiac & Cardiovascular Systems
Toshiki Kuno, Tomohiro Fujisaki, Satoshi Shoji, Yuki Sahashi, Yusuke Tsugawa, Masao Iwagami, Hisato Takagi, Alexandros Briasoulis, Pierre Deharo, Thomas Cuisset, Azeem Latib, Shun Kohsaka, Deepak L. Bhatt
Summary: Compared with guided selection of DAPT, unguided de-escalation of DAPT decreases bleeding risk in patients after acute coronary syndrome.
CIRCULATION-CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Medicine, General & Internal
Shingo Fukuma, Mitsuru Mukaigawara, Toshiaki Iizuka, Yusuke Tsugawa
Summary: This study investigated the effect of a population-level health guidance intervention on healthcare utilisation and spending in Japan. The study found that the intervention was associated with a decrease in outpatient visits, but had no effect on medication use, hospitalisation use, or healthcare spending.
Article
Medicine, General & Internal
Atsushi Miyawaki, Ryo Ikesu, Yasuharu Tokuda, Rei Goto, Yasuki Kobayashi, Kazuaki Sano, Yusuke Tsugawa
Summary: This study aimed to investigate the use and factors associated with low-value care in Japan. The study utilized a multicentre observational design and claims data from 242 large acute care hospitals in Japan. The findings revealed that approximately 7.5% of patients received low-value care services based on the broader definition, while about 4.9% received such services based on the narrower definition. There was no significant change in the prevalence of low-value services between 2015 and 2019. Factors such as hospital size, age, sex, and comorbidities were associated with the likelihood of receiving low-value care.
Article
Health Care Sciences & Services
Sho Okiyama, Memori Fukuda, Masashi Sode, Wataru Takahashi, Masahiro Ikeda, Hiroaki Kato, Yusuke Tsugawa, Masao Iwagami
Summary: In this study, a deep learning model was developed to diagnose influenza infection using pharyngeal images and clinical information. The model showed high accuracy and specificity, outperforming three physicians. It has the potential to assist physicians in timely diagnosis of influenza.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Geriatrics & Gerontology
Hiroshi Gotanda, Yusuke Tsugawa, Haiyong Xu, David B. B. Reuben
Summary: Background: Despite potential negative consequences, little is known about how individuals with dementia perceive life satisfaction. This study found that, after adjusting for individual characteristics, there was no difference in life satisfaction between individuals with probable dementia and those without. However, dementia status was associated with lower life satisfaction through the mediation of limitations in daily living activities.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Medicine, General & Internal
Itsuki Osawa, Tadahiro Goto, Takahiro Tabuchi, Hayami K. Koga, Yusuke Tsugawa
Summary: The study found that during the COVID-19 pandemic, factors such as meaning in life, having a spouse, trust in neighbors, and female gender were positively associated with happiness, while self-reported poor health, anxiety about future household income, psychiatric diseases except depression, and feeling isolated were negatively associated with happiness. Interventions that improve social capital, pandemic control, and economic stimuli may effectively enhance psychological well-being during the COVID-19 pandemic.
Article
Emergency Medicine
Atsushi Miyawaki, Anupam B. Jena, Laura G. Burke, Jose F. Figueroa, Yusuke Tsugawa
Summary: The study aimed to determine the association between emergency physicians' ages and patient mortality after emergency department visits. An observational study was conducted on a 20% random sample of Medicare fee-for-service beneficiaries aged 65 to 89 years. The findings showed that patients treated by younger emergency physicians had lower mortality rates compared with those treated by older physicians.
ANNALS OF EMERGENCY MEDICINE
(2023)
Article
Medicine, General & Internal
Atsushi Miyawaki, Anupam B. Jena, Nate Gross, Yusuke Tsugawa
Summary: “There were no significant differences in the quality and costs of care between allopathic and osteopathic hospitalists when treating elderly Medicare patients.”
ANNALS OF INTERNAL MEDICINE
(2023)
Article
Medicine, General & Internal
Dan P. Ly, Mariah B. Blegen, Melinda M. Gibbons, Keith C. Norris, Yusuke Tsugawa
Summary: In this retrospective cohort study, it was found that overall postoperative mortality was higher among Black men compared with White men, White women, and Black women.This suggests that there are disparities in healthcare outcomes based on race and gender in the United States.
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Article
Public, Environmental & Occupational Health
Shingo Fukuma, Ryo Ikesu, Toshiaki Iizuka, Yusuke Tsugawa
Summary: This study examined the impact of left-digit bias based on patients' age on the initial diagnosis of stroke. The results showed a discontinuous change in the ordering of imaging tests for stroke at the age threshold of 40 years old, which only affected male patients.
SOCIAL SCIENCE & MEDICINE
(2023)
Article
Medicine, General & Internal
Shingo Fukuma, Hirotaka Kato, Reo Takaku, Yusuke Tsugawa
Summary: Using a regression discontinuity design, this study investigated the impact of no cost sharing on paediatric care usage and health outcomes in Japan. The results showed that no cost sharing was associated with increased outpatient care usage and spending, but did not affect inpatient care usage. Notably, the effect of no cost-sharing policy was greater among children from high-income households, suggesting that it disproportionately benefits higher-income families and may contribute to larger disparities.
Article
Education, Scientific Disciplines
Naoki Ito, Sakina Kadomatsu, Mineto Fujisawa, Kiyomitsu Fukaguchi, Ryo Ishizawa, Naoki Kanda, Daisuke Kasugai, Mikio Nakajima, Tadahiro Goto, Yusuke Tsugawa
Summary: This study assessed the accuracy of GPT-4 and physicians in diagnosing and triaging health conditions, and examined the performance differences based on patient race and ethnicity. The results showed that GPT-4 had comparable accuracy to physicians in diagnosis and triage, and its performance did not vary based on patient race and ethnicity.
JMIR MEDICAL EDUCATION
(2023)
Article
Medicine, General & Internal
Christopher J. D. Wallis, Angela Jerath, Ryo Ikesu, Raj Satkunasivam, Justin B. Dimick, John Orav, E. John Orav, Melinda Maggard-Gibbons, Ruixin Li, Arghavan Salles, Zachary Klaassen, Natalie Coburn, Barbara L. Bass, Allan S. Detsky, Yusuke Tsugawa
Summary: Patient-surgeon gender concordance does not appear to have a significant impact on post-operative mortality rates among patients in the United States. However, there may be a slight decrease in mortality for female patients when their surgeon is of the same gender, but a slight increase in mortality for male patients. Additionally, there is no evidence to suggest that patient-surgeon gender concordance affects operative mortality for non-elective procedures.
BMJ-BRITISH MEDICAL JOURNAL
(2023)