4.5 Article

Analysis of retinal fundus images for grading of diabetic retinopathy severity

Journal

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
Volume 49, Issue 6, Pages 693-700

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s11517-011-0734-2

Keywords

Diabetic retinopathy grading; Foveal avascular zone; Medical image analysis; Retinal fundus images

Funding

  1. Ministry of Science, Technology and Innovation [TF0206C129]

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Diabetic retinopathy (DR) is a sight threatening complication due to diabetes mellitus that affects the retina. In this article, a computerised DR grading system, which digitally analyses retinal fundus image, is used to measure foveal avascular zone. A v-fold cross-validation method is applied to the FINDeRS database to evaluate the performance of the DR system. It is shown that the system achieved sensitivity of > 84%, specificity of > 97% and accuracy of > 95% for all DR stages. At high values of sensitivity (> 95%), specificity (> 97%) and accuracy (> 98%) obtained for No DR and severe NPDR/PDR stages, the computerised DR grading system is suitable for early detection of DR and for effective treatment of severe cases.

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