Rapamycin Attenuates Endothelial Apoptosis Induced by Low Shear Stress via mTOR and Sestrin1 Related Redox Regulation

P66SHC and Ageing: ROS and TOR?

(2016) Giovambattista Pani   Aging-US

Rapamycin Reduces Reactive Oxygen Species in Cultured Human Corneal Endothelial Cells

(2012) Young Joo Shin et al.   CURRENT EYE RESEARCH

Role of Endothelial Shear Stress in Stent Restenosis and Thrombosis

(2012) Konstantinos C. Koskinas et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Rapamycin inhibits hydrogen peroxide-induced loss of vascular contractility

(2011) Ge Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Acute Effects of Nicardipine and Esmolol on The Cardiac Cycle, Intracardiac Hemodynamic and Endothelial Shear Stress in Patients With Unstable Angina Pectoris and Moderate Coronary Stenosis: Results From Single Center, Randomized Study

(2011) Shao-Liang Chen et al.   Cardiovascular Therapeutics

Inhibition of human in-stent restenosis: a molecular view

(2011) Arturo Giordano et al.   CURRENT OPINION IN PHARMACOLOGY

Vascular Inflammation and Repair

(2011) Teruo Inoue et al.   JACC-Cardiovascular Interventions

Hyperactive S6K1 Mediates Oxidative Stress and Endothelial Dysfunction in Aging: Inhibition by Resveratrol

(2011) Angana G. Rajapakse et al.   PLoS One

Animal, In Vitro, and Ex Vivo Models of Flow-Dependent Atherosclerosis: Role of Oxidative Stress

(2010) Amir Rezvan et al.   ANTIOXIDANTS & REDOX SIGNALING

Aging: ROS or TOR

(2010) Mikhail V Blagosklonny   CELL CYCLE

FoxOs Inhibit mTORC1 and Activate Akt by Inducing the Expression of Sestrin3 and Rictor

(2010) Chia-Chen Chen et al.   DEVELOPMENTAL CELL

Stressin' Sestrins take an aging fight

(2010) Andrei V. Budanov et al.   EMBO Molecular Medicine

The Effect of Shear Stress on Neointimal Response Following Sirolimus- and Paclitaxel-Eluting Stent Implantation Compared With Bare-Metal Stents in Humans

(2010) Michail I. Papafaklis et al.   JACC-Cardiovascular Interventions

Contradictory Shear Stress Distribution Prevents Restenosis after Provisional Stenting for Bifurcation Lesions

(2010) JUNE-JIE ZHANG et al.   JOURNAL OF INTERVENTIONAL CARDIOLOGY

Distribution and Magnitude of Shear Stress after Coronary Bifurcation Lesions Stenting with the Classical Crush Technique: A New Predictor for In-Stent Restenosis

(2010) ZUO-YING HU et al.   JOURNAL OF INTERVENTIONAL CARDIOLOGY

Tissue factor pathway inhibitor-2 is induced by fluid shear stress in vascular smooth muscle cells and affects cell proliferation and survival

(2010) Johan Ekstrand et al.   JOURNAL OF VASCULAR SURGERY

Sestrin as a Feedback Inhibitor of TOR That Prevents Age-Related Pathologies

(2010) J. H. Lee et al.   SCIENCE

Posttransplantation Therapeutic Rapamycin Concentration Protects Nitric Oxide–Related Vascular Endothelial Function: Comparative Effects in Rat Thoracic Aorta and Coronary Endothelial Cell Culture

(2010) A. Parlar et al.   TRANSPLANTATION PROCEEDINGS

Oscillatory Flow-induced Proliferation of Osteoblast-like Cells Is Mediated by αvβ3and β1Integrins through Synergistic Interactions of Focal Adhesion Kinase and Shc with Phosphatidylinositol 3-Kinase and the Akt/mTOR/p70S6K Pathway

(2009) Ding-Yu Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rosiglitazone acts as a neuroprotectant in retinal cells via up-regulation of sestrin-1 and SOD-2

(2009) Francesca Doonan et al.   JOURNAL OF NEUROCHEMISTRY

Rapamycin reduces high-amplitude, mechanical stretch-induced apoptosis in pulmonary microvascular endothelial cells

(2009) Uwe Raaz et al.   MICROVASCULAR RESEARCH

Tumor Protein 53-Induced Nuclear Protein 1 Is a Major Mediator of p53 Antioxidant Function

(2008) C. E. Cano et al.   CANCER RESEARCH

In human endothelial cells rapamycin causes mTORC2 inhibition and impairs cell viability and function

(2008) Amelia Barilli et al.   CARDIOVASCULAR RESEARCH

p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling

(2008) Andrei V. Budanov et al.   CELL

Drug Eluting Stents: Friend or Foe? A Review of Cellular Mechanisms Behind the Effects of Paclitaxel and Sirolimus Eluting Stents

(2008) Subroto Chatterjee et al.   CURRENT DRUG METABOLISM

A Novel Antioxidant Function for the Tumor-Suppressor Gene p53 in the Retinal Ganglion Cell

(2008) J. C. O'Connor et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Sirolimus-Induced Vascular Dysfunction

(2008) Alexander Jabs et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY