4.5 Article

The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats

Journal

MEDIATORS OF INFLAMMATION
Volume 2012, Issue -, Pages -

Publisher

HINDAWI LTD
DOI: 10.1155/2012/692467

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Funding

  1. Natural Science Foundation of China [40590392]
  2. Natural Science Foundation of GuangDong Province, China [9151802003000001]

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In the present study, we assessed the treatment effects of PBDE-209 administration on the immune function in rats during pregnancy and lactation. We harvested the blood and organs for flow cytometry, viability assay, enzyme-linked immunosorbent assay, and histological evaluation. The results of this study were the PBDE-209 exposure during pregnancy and lactation impairs immune function in rats. The results may contribute to understanding the mechanism of PBDE-209 in immune function.

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